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The percentage of patients hospitalized due to hyponatremia is getting higher. Hyponatremia is the deficiency of sodium electrolyte in the human serum. This deficiency might indulge adverse effects and also associated with longer hospital…

定量方法 · 定量生物学 2021-06-15 Prasannavenkatesan Theerthagiri

Sulfuric acid aerosol is suspected to be a major contributor to mortality and morbidity associated with air pollution. The objective of the study is to determine if exposure of human participants to anticipated levels of sulfuric acid…

应用统计 · 统计学 2019-06-26 Lamin Juwara , Jennifer Boateng

Background: Postpartum urinary incontinence (PUI) is a common issue among postnatal women. Previous studies identified potential related variables, but lacked analysis on certain intrinsic and extrinsic patient variables during pregnancy.…

Objective: To develop prognostic survival models for predicting adverse outcomes after catheter ablation treatment for non-valvular atrial fibrillation (AF). Methods: We used a linked dataset including hospital administrative data,…

机器学习 · 计算机科学 2024-02-19 Juan C. Quiroz , David Brieger , Louisa Jorm , Raymond W Sy , Benjumin Hsu , Blanca Gallego

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

机器学习 · 计算机科学 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

Chronic pain (CP) and opioid use disorder (OUD) are common and interrelated chronic medical conditions. Currently, there is a paucity of evidence-based integrated treatments for CP and OUD among individuals receiving medication for opioid…

Causal understanding is a fundamental goal of evidence-based medicine. When randomization is impossible, causal inference methods allow the estimation of treatment effects from retrospective analysis of observational data. However, such…

机器学习 · 计算机科学 2024-11-06 Samuel Lee , Zach Wood-Doughty

Airway constriction and blockage in obstructive lung diseases cause ventilation heterogeneity and create barriers to effective drug deposition. Established computational particle-deposition models have not accounted for these impacts of…

组织与器官 · 定量生物学 2024-10-17 James D. Shemilt , Alex Horsley , Jim M. Wild , Oliver E. Jensen , Alice B. Thompson , Carl A. Whitfield

Mental disorders impact the lives of millions of people globally, not only impeding their day-to-day lives but also markedly reducing life expectancy. This paper addresses the persistent challenge of predicting mortality in patients with…

机器学习 · 计算机科学 2023-10-19 Sean Kim , Samuel Kim

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

Globally, the number of obese patients has doubled due to sedentary lifestyles and improper dieting. The tremendous increase altered human genetics, and health. According to the world health organization, Life expectancy dropped from 80 to…

定量方法 · 定量生物学 2022-08-08 Amin Gasmi

Patient status, angiographic and procedural characteristics encode crucial signals for predicting long-term outcomes after percutaneous coronary intervention (PCI). The aim of the study was to develop a predictive model for assessing the…

机器学习 · 计算机科学 2025-12-30 Daniil Burakov , Ivan Petrov , Dmitrii Khelimskii , Ivan Bessonov , Mikhail Lazarev

ML is playing an increasingly crucial role in estimating causal effects of treatments on outcomes from observational data. Many ML methods (`causal estimators') have been proposed for this task. All of these methods, as with any ML…

机器学习 · 计算机科学 2025-10-06 Damian Machlanski , Spyridon Samothrakis , Paul Clarke

Respiratory failure is the one of major causes of death in critical care unit. During the outbreak of COVID-19, critical care units experienced an extreme shortage of mechanical ventilation because of respiratory failure related syndromes.…

机器学习 · 计算机科学 2021-09-08 Yilin Yin , Chun-An Chou

Smoking continues to be a major preventable cause of death worldwide, affecting millions through damage to the heart, metabolism, liver, and kidneys. However, current medical screening methods often miss the early warning signs of…

机器学习 · 计算机科学 2026-01-27 Vaskar Chakma , MD Jaheid Hasan Nerab , Abdur Rouf , Abu Sayed , Hossem MD Saim , Md. Nournabi Khan

Pulmonary drug delivery systems rely on inhalation of drug-laden aerosols produced from aerosol generators such as inhalers, nebulizers etc. On deposition, the drug molecules diffuse in the mucus layer and are also subjected to mucociliary…

组织与器官 · 定量生物学 2022-01-14 Aranyak Chakravarty , Mahesh V. Panchagnula , Alladi Mohan , Neelesh A. Patankar

Long-term adherence to medication is a critical factor in preventing chronic diseases, such as cardiovascular disease. To address poor adherence, physicians may recommend adherence-improving interventions; however, such interventions are…

最优化与控制 · 数学 2026-02-24 Daniel Otero-Leon , Mariel Lavieri , Brian Denton , Jeremy Sussman , Rodney Hayward

Opioid addiction has become a global epidemic and a national health crisis in recent years, with the number of opioid overdose fatalities steadily increasing since the 1990s. In contrast to the dynamics of a typical illicit drug or disease…

种群与进化 · 定量生物学 2019-05-03 Nicholas A. Battista , Leigh B. Pearcy , W. Christopher Strickland

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

定量方法 · 定量生物学 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

机器学习 · 计算机科学 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer