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In-house feeding system (IHF, a low dietary fiber source) may cause altered cecal microbiota composition and inflammatory responses in meat geese via increased endotoxemia (lipopolysaccharides) with reduced intestinal alkaline phosphatase…

Background Genetic parameters of feeding behaviours traits from electronic feeding stations in relation to feed efficiency have been widely explored. However, genetic determinism of the circadian rhythm of feed intake throughout the…

种群与进化 · 定量生物学 2026-03-20 Lucile Riaboff , Ingrid David

The gut-muscle axis has been proposed to link gut microbiota with skeletal muscle physiology, yet its universality across livestock species remains unclear. Using aged laying hens, a livestock model with a relatively short digestive tract,…

Biomolecular condensates organize biochemical processes by spatially concentrating molecules while allowing for dynamic exchange with their surroundings. However, transport across their interface can be strongly attenuated, leading to…

生物物理 · 物理学 2026-03-27 Oihan Joyot , Zoé Ferrand , Fernando Muzzopappa , Pierre Weiss , Fabian Erdel

Short-chain fatty acids (SCFAs), including acetate, propionate and butyrate, are organic fatty-acids that are produced when indigested carbohydrates are fermented in the colon by gut-bacteria. Butyrate is especially considered a beneficial…

仪器与探测器 · 物理学 2019-09-26 Martin Längkvist , Amy Loutfi , Igancio Rangel , Johnny Karlsson , Robert Jan Brummer

The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent microbiome multiomics studies, particularly paired…

统计方法学 · 统计学 2025-04-09 Haoran Shi , Yue Wang , Dan Cheng

The neonatal intensive care unit (NICU) experience is known to be one of the most crucial factors that drive preterm infant's neurodevelopmental and health outcomes. It is hypothesized that stressful early life experience of very preterm…

统计方法学 · 统计学 2019-10-10 Zhe Sun , Wanli Xu , Xiaomei Cong , Gen Li , Kun Chen

Proteins carry out biological functions through the coordinated action of groups of residues organized into structural arrangements. These arrangements, which we refer to as protein units, exist at an intermediate scale, being larger than…

生物大分子 · 定量生物学 2026-04-17 Gökçe Uludoğan , Buse Giledereli , Elif Ozkirimli , Arzucan Özgür

Mammalian gut microbiomes are essential for host functions like digestion, immunity, and nutrient utilization. This study examines the gut microbiome of horses, donkeys, and their hybrids, mules and hinnies, to explore the role of…

基因组学 · 定量生物学 2024-07-09 Yihang Zhou

The villi and crypts of the gastrointestinal tract increase the effective surface area of the intestinal mucosa, potentially enhancing nutrient absorption. It is commonly assumed that this is their primary function, and that a higher villi…

The current global food system produces substantial waste and carbon emissions while exacerbating the effects of global hunger and protein deficiency. This study aims to address these challenges by exploring the use of lignocellulosic…

生物物理 · 物理学 2024-07-02 Mason Banks , Mark Taylor , Miao Guo

The so-called gut-brain axis has stimulated extensive research on microbiomes. One focus is to assess the association between certain clinical outcomes and the relative abundances of gut microbes, which can be presented as sub-compositional…

统计方法学 · 统计学 2020-06-02 Xiaokang Liu , Xiaomei Cong , Gen Li , Kendra Maas , Kun Chen

Gut microbiota plays a crucial role in modulating pig development and health, and gut microbiota characteristics are associated with differences in feed efficiency. To answer open questions in feed efficiency analysis, biologists seek to…

Adipose tissue (AT) transcriptome studies provide holistic pictures of adaptation to weight and related bioclinical settings changes. Objective To implement AT gene expression profiling and investigate the link between changes in…

We examined the changes in swimming behaviour of the bacterium Rhodobacter sphaeroides in response to stepwise changes in a nutrient (propionate), following the prestimulus motion, the initial response and the adaptation to the sustained…

定量方法 · 定量生物学 2007-05-23 Anna A. Chernova , Judith P. Armitage , Helen L. Packer , Philip K. Maini

Intestinal apoptosis and expression of apoptosis inducers - the cytokines TNFalpha, TGFbeta1 - and the intestinal transcription factor Cdx2, were studied according to two different metabolic and hormonal phases which characterize long-term…

种群与进化 · 定量生物学 2007-05-23 C. Habold , C. Foltzer-Jourdainne , Y. Le Maho , J. H. Lignot

Two proteins, one belonging to the mainly alpha class and the other belonging to the alpha/beta class, are selected to test a kinetic mechanism for protein folding. Targeted molecular dynamics is applied to generate folding pathways for…

生物物理 · 物理学 2011-01-04 Leonor Cruzeiro

Scope: To study the effect of variation in dietary vitamin A (VA) content on its hepatic and intestinal metabolism. Methods and results: Adult female and male rats were fed with diets containing 400, 2300, or 9858 IU/kg VA for 31-33 weeks.…

Translation of proteins is a fundamental part of gene expression that is mediated by ribosomes. As ribosomes significantly contribute to both cellular mass and energy consumption, achieving efficient management of the ribosome population is…

亚细胞过程 · 定量生物学 2024-04-18 Clément Soubrier , Eric Foxall , Luca Ciandrini , Khanh Dao Duc

The gut-brain axis has emerged as a key player in the regulation of brain function and cognitive health. Gut microbiota dysbiosis has been observed in preclinical models of Alzheimer's disease and patients. Manipulating the composition of…

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