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Wearable technology for the automatic detection of gait events has recently gained growing interest, enabling advanced analyses that were previously limited to specialist centres and equipment (e.g., instrumented walkway). In this study, we…

信号处理 · 电气工程与系统科学 2020-09-01 Matteo Gadaleta , Giulia Cisotto , Michele Rossi , Rana Zia Ur Rehman , Lynn Rochester , Silvia Del Din

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance for diagnosing, monitoring and developing disease modifying…

Oculomotor alterations constitute a promising biomarker to detect and characterize Parkinson's disease (PD), even in prodromal stages. Currently, only global and simplified eye movement trajectories are employed to approximate the complex…

计算机视觉与模式识别 · 计算机科学 2025-02-26 Juan Niño , Luis Guayacán , Santiago Gómez , Fabio Martínez

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

定量方法 · 定量生物学 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Accurate lesion detection in computer tomography (CT) slices benefits pathologic organ analysis in the medical diagnosis process. More recently, it has been tackled as an object detection problem using the Convolutional Neural Networks…

计算机视觉与模式识别 · 计算机科学 2019-07-10 Qingbin Shao , Lijun Gong , Kai Ma , Hualuo Liu , Yefeng Zheng

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

机器学习 · 计算机科学 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

图像与视频处理 · 电气工程与系统科学 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Amyotrophic Lateral Sclerosis (ALS) and Myopathy present considerable challenges in the realm of neuromuscular disorder diagnostics. In this study, we employ advanced deep-learning techniques to address the detection of ALS and Myopathy,…

信号处理 · 电气工程与系统科学 2024-10-30 Md. Toufiqur Rahman , Minhajur Rahman , Celia Shahnaz

People with Parkinson's Disease (PD) can slow the progression of their symptoms with physical therapy. However, clinicians lack insight into patients' motor function during daily life, preventing them from tailoring treatment protocols to…

Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of…

机器学习 · 计算机科学 2019-01-23 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

计算机视觉与模式识别 · 计算机科学 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Falls are detrimental to people with Parkinson's Disease (PD) because of the potentially severe consequences to the patients' quality of life. While many studies have attempted to predict falls/non-falls, this study aimed to determine…

应用统计 · 统计学 2019-10-07 Sarini Abdullah , James McGree , Nicole White , Kerrie Mengersen , Graham Kerr

More than 90% of the Parkinson Disease (PD) patients suffer from vocal disorders. Speech impairment is already indicator of PD. This study focuses on PD diagnosis through voiceprint features. In this paper, a method based on Deep Neural…

声音 · 计算机科学 2018-12-18 Zhijing Xu , Juan Wang , Ying Zhang , Xiangjian He

We study on-device time-series analysis for gait detection in Parkinson's disease (PD) from short windows of triaxial acceleration, targeting resource-constrained wearables and edge nodes. We compare magnitude thresholding to three 1D CNNs…

机器学习 · 计算机科学 2025-12-15 Andrea Procopio , Marco Esposito , Sara Raggiunto , Andrey Gizdov , Alberto Belli , Paola Pierleoni

Background: Wide-field calcium imaging (WFCI) with genetically encoded calcium indicators allows for spatiotemporal recordings of neuronal activity in mice. When applied to the study of sleep, WFCI data are manually scored into the sleep…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Xiaohui Zhang , Eric C. Landsness , Hanyang Miao , Wei Chen , Michelle Tang , Lindsey M. Brier , Joseph P. Culver , Jin-Moo Lee , Mark A. Anastasio

Structural MRI and PET imaging play an important role in the diagnosis of Alzheimer's disease (AD), showing the morphological changes and glucose metabolism changes in the brain respectively. The manifestations in the brain image of some…

图像与视频处理 · 电气工程与系统科学 2023-08-11 Yanteng Zhang , Qizhi Teng , Xiaohai He , Tong Niu , Lipei Zhang , Yan Liu , Chao Ren

Stress is a physiological state that hampers mental health and has serious consequences to physical health. Moreover, the COVID-19 pandemic has increased stress levels among people across the globe. Therefore, continuous monitoring and…

信号处理 · 电气工程与系统科学 2021-08-09 Nafiul Rashid , Luke Chen , Manik Dautta , Abel Jimenez , Peter Tseng , Mohammad Abdullah Al Faruque

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

机器学习 · 计算机科学 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

Video-based assessments offer a scalable pathway for remote Parkinson's disease (PD) screening. While traditional approaches rely on handcrafted features mimicking clinical scales, recent advances in video foundation models (VFMs) enable…