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This study introduces an inverse behavioral optimization framework that integrates QALY-based health outcomes, ROI-driven incentives, and adaptive behavioral learning to quantify how policy design shapes national healthcare performance.…

数理金融 · 定量金融 2025-10-28 Jinho Cha , Justin Yu , Junyeol Ryu , Eunchan Daniel Cha , Hyeyoung Hwang

We offer a pragmatic model to operationalize responsible, secure, and sustainable healthcare AI, aligning world-class technical excellence with organizational readiness. The framework includes five key pillars - Leadership & Strategy, MLOps…

计算机与社会 · 计算机科学 2025-10-21 Jimmy Joseph

The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…

统计方法学 · 统计学 2026-01-07 Richik Chakraborty

One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…

应用统计 · 统计学 2018-12-04 Luis F. Campos , Mark E. Glickman , Kristen B. Hunter

In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal…

人工智能 · 计算机科学 2018-10-09 Casey C. Bennett , Kris Hauser

This study reveals the important role of prevention care and medication adherence in reducing hospitalizations. By using a structured dataset of 1,171 patients, four machine learning models Logistic Regression, Gradient Boosting, Random…

机器学习 · 计算机科学 2025-04-11 Yixin Zhang , Yisong Chen

Non-adherence to medications is a critical concern since nearly half of patients with chronic illnesses do not follow their prescribed medication regimens, leading to increased mortality, costs, and preventable human distress. Amongst stage…

Dynamic microsimulation has long been recognized as a powerful tool for policy analysis, but in fact most major health policy simulations lack path dependency, a critical feature for evaluating policies that depend on accumulated outcomes…

应用统计 · 统计学 2025-06-04 Adrienne M. Propp , Raffaele Vardavas , Carter C. Price , Kandice A. Kapinos

In this paper, we present an adaptive investment strategy for environments with periodic returns on investment. In our approach, we consider an investment model where the agent decides at every time step the proportion of wealth to invest…

计算工程、金融与科学 · 计算机科学 2008-12-01 J. -Emeterio Navarro

We consider a real-world chemotherapy scheduling template design problem, where we cluster patient types into groups and find a representative time-slot duration for each group to accommodate all patient types assigned to that group, aiming…

最优化与控制 · 数学 2025-10-14 Qing Zhu , Xian Yu , Yu-Li Huang

Problem Definition: Managing inpatient flow in large hospital systems is challenging due to the complexity of assigning randomly arriving patients -- either waiting for primary units or being overflowed to alternative units. Current…

最优化与控制 · 数学 2026-05-08 Jingjing Sun , Jim Dai , Pengyi Shi

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

The valuation of Cyber Threat Intelligence (CTI) remains a persistent challenge due to the problem of negative evidence: successful threat prevention results in non-events that generate minimal observable financial impact, making CTI…

密码学与安全 · 计算机科学 2025-07-24 Matteo Strada

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Long-term adherence to medication is a critical factor in preventing chronic diseases, such as cardiovascular disease. To address poor adherence, physicians may recommend adherence-improving interventions; however, such interventions are…

最优化与控制 · 数学 2026-02-24 Daniel Otero-Leon , Mariel Lavieri , Brian Denton , Jeremy Sussman , Rodney Hayward

Adherence can be defined as "the extent to which patients take their medications as prescribed by their healthcare providers"[Osterberg and Blaschke, 2005]. World Health Organization's reports point out that, in developed countries, only…

机器学习 · 计算机科学 2018-11-30 Thomas Janssoone , Clémence Bic , Dorra Kanoun , Pierre Hornus , Pierre Rinder

Individual-level effectiveness and healthcare resource use (HRU) data are routinely collected in trial-based economic evaluations. While effectiveness is often expressed in terms of utility scores derived from some health-related quality of…

统计方法学 · 统计学 2024-07-31 Andrea Gabrio

Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…

统计方法学 · 统计学 2021-04-26 Kristen B. Hunter , Mark E. Glickman , Luis F. Campos

We develop a unified model in which AI adoption in financial markets generates systemic risk through three mutually reinforcing channels: performative prediction, algorithmic herding, and cognitive dependency. Within an extended rational…

计算金融 · 定量金融 2026-04-07 Shuchen Meng , Xupeng Chen

A critical challenge facing clinicians managing chronic disease interventions is sustaining long-run patient health given limited information and resources. Digital therapeutics (DTs) provide a cost-effective way to manage interventions at…

机器学习 · 计算机科学 2026-05-26 Eric Pulick , Stephanie Carpenter , Matthew Buman , Yonatan Mintz
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