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相关论文: A Novel Helical Thin-Film Flow Diverter: Design, F…

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Rapid and accurate simulation of cerebral aneurysm flow modifications by flow diverters (FDs) can help improving patient-specific intervention and predicting treatment outcome. However, with explicit FD devices being placed in…

流体动力学 · 物理学 2021-06-14 Armin Abdehkakha , Adam L. Hammond , Tatsat R. Patel , Adnan H. Siddiqui , Gary Dargush , Hui Meng

Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…

计算工程、金融与科学 · 计算机科学 2023-01-23 Beatrice Bisighini , Miquel Aguirre , Marco Evangelos Biancolini , Federica Trovalusci , David Perrin , Stephane Avril , Baptiste Pierrat

During intracranial aneurysm (IA) treatment with Diverters (FDs), the device/parent artery diameters ratio may influence the ability of the device to induce aneurysm healing response. Oversized FDs are safer to deploy but may not induce…

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

计算工程、金融与科学 · 计算机科学 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu

Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their…

流体动力学 · 物理学 2023-08-17 Aurèle Goetz , Pablo Jeken Rico , Yves Chau , Jacques Sédat , Aurélien Larcher , Elie Hachem

Most Computational Fluid Dynamics (CFD) studies of hemodynamics in intracranial aneurysms are based on the assumption of laminar flow due to a relatively low (below 500) parent artery Reynolds number. A few studies have recently…

流体动力学 · 物理学 2015-12-09 Kartik Jain , Sabine Roller , Kent-Andre Mardal

Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…

Predicting the long-term success of endovascular interventions in the clinical management of cerebral aneurysms requires detailed insight into the patient-specific physiological conditions. In this work, we not only propose numerical…

A unified Smoothed Particle Hydrodynamics (SPH) simulation framework for coronary stent implantation is developed, which unifies weakly compressible hemodynamics, Neo-Hookean solids, and stent-artery contacts, based on a multi-resolution…

流体动力学 · 物理学 2025-11-13 Jinlei Zhou , Sukang Peng , Yongchuan Yu , Dong Wu , Xiangyu Hu

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…

流体动力学 · 物理学 2024-10-17 Thien-Tam Nguyen , Davina Kasperski , Phat Kim Huynh , Trung Quoc Le , Trung Bao Le

Flow fluctuations have recently emerged as a promising hemodynamic metric for understanding the rupture risk of intracranial aneurysms. Several investigations have reported in the literature corresponding flow instabilities using…

流体动力学 · 物理学 2023-06-05 Feng Huang , Seyed Ali Hosseini , Gabor Janiga , Dominique Thévenin

In the case of vector flow imaging systems, the most employed flow estimation techniques are the directional beamforming based cross correlation and the triangulation-based autocorrelation. However, the directional beamforming-based…

信号处理 · 电气工程与系统科学 2022-06-07 A. N. Madhavanunni , Mahesh Raveendranatha Panicker

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

流体动力学 · 物理学 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…

流体动力学 · 物理学 2021-01-27 Georgios Bletsos , Niklas Kühl , Thomas Rung

Numerical simulations have been extensively used in the past two decades for the study of intracranial aneurysms (IAs), a dangerous disease that occurs in the arteries that reach the brain. They may affect up to 10 % of the world's…

流体动力学 · 物理学 2022-10-12 Iago Oliveira , Philip Cardiff , Carlos E. Baccin , José Gasche

In this work we study the hemodynamics in a stented artery connected either to a collateral artery or to an aneurysmal sac. The blood flow is driven by the pressure drop. Our aim is to characterize the flow-rate and the pressure in the…

偏微分方程分析 · 数学 2010-07-07 Vuk Milisic

In Angiographic Parametric Imaging (API), accurate estimation of parameters from Time Density Curves (TDC) is crucial. However, these estimations are often marred by errors arising from factors such as patient motion, procedural…

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