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Designing functional protein sequences that satisfy multiple desired properties is a core research focus of protein engineering. Prior methods struggle with inability or inefficiency when dealing with numerous, often conflicting,…

生物大分子 · 定量生物学 2026-05-08 Zitai Kong , Yifan Dong , Yixuan Wu , Zhaokang Liang , Jian Wu , Hongxia Xu

AllReduce is a technique in distributed computing which saw use in many critical applications of deep learning. Existing methods of AllReduce scheduling oftentimes lack flexibility due to being topology-specific or relying on extensive…

网络与互联网体系结构 · 计算机科学 2025-03-28 Yufan Wei , Mickel Liu , Wenfei Wu

Generative models, including diffusion and flow-based models, often exhibit systematic biases that degrade sample quality, particularly in high-dimensional settings. We revisit refinement methods and show that effective bias correction can…

机器学习 · 计算机科学 2026-01-30 Xin Peng , Ang Gao

Fined-grained anomalous cell detection from affected tissues is critical for clinical diagnosis and pathological research. Single-cell sequencing data provide unprecedented opportunities for this task. However, current anomaly detection…

机器学习 · 计算机科学 2024-05-01 Kaichen Xu , Yueyang Ding , Suyang Hou , Weiqiang Zhan , Nisang Chen , Jun Wang , Xiaobo Sun

Element-wise activation functions play a critical role in deep neural networks via affecting the expressivity power and the learning dynamics. Learning-based activation functions have recently gained increasing attention and success. We…

机器学习 · 计算机科学 2020-10-05 Dengsheng Chen , Jun Li , Kai Xu

Complex single-objective bounded problems are often difficult to solve. In evolutionary computation methods, since the proposal of differential evolution algorithm in 1997, it has been widely studied and developed due to its simplicity and…

神经与进化计算 · 计算机科学 2024-04-26 Sichen Tao , Ruihan Zhao , Kaiyu Wang , Shangce Gao

Discrete normalizing flows are promising generative models with advantages such as analytical log-likelihood computation and end-to-end training. However, the architectural constraints to ensure invertibility and tractable Jacobian…

机器学习 · 计算机科学 2026-05-06 Jiaru Zhang , Juanwu Lu , Xiaoyu Wu , Ziran Wang , Ruqi Zhang

Linear recurrent neural networks enable powerful long-range sequence modeling with constant memory usage and time-per-token during inference. These architectures hold promise for streaming applications at the edge, but deployment in…

In diffusion models, samples are generated through an iterative refinement process, requiring hundreds of sequential model evaluations. Several recent methods have introduced approximations (fewer discretization steps or distillation) to…

机器学习 · 计算机科学 2024-12-12 Nikil Roashan Selvam , Amil Merchant , Stefano Ermon

We introduce a generative learning framework to model high-dimensional parametric systems using gradient guidance and virtual observations. We consider systems described by Partial Differential Equations (PDEs) discretized with structured…

机器学习 · 计算机科学 2024-08-02 Han Gao , Sebastian Kaltenbach , Petros Koumoutsakos

We introduce the Equilibrated Averaging Residual Method (EARM), a unified equilibrated flux-recovery framework for elliptic interface problems that applies to a broad class of finite element discretizations. The method is applicable in both…

数值分析 · 数学 2026-01-06 Cuiyu He

An adaptive refinement strategy, based on an equilibrated flux a posteriori error estimator, is proposed in the context of defeaturing problems. Defeaturing consists of removing features from complex domains to simplify mesh generation and…

数值分析 · 数学 2026-03-04 Annalisa Buffa , Denise Grappein , Rafael Vázquez

Neural networks have achieved remarkable performance across a wide range of tasks, yet they remain susceptible to adversarial perturbations, which pose significant risks in safety-critical applications. With the rise of multimodality,…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Xinxin Liu , Zhongliang Guo , Siyuan Huang , Chun Pong Lau

Person re-identification (ReID) aims to re-identify a person from non-overlapping camera views. Since person ReID data contains sensitive personal information, researchers have adopted federated learning, an emerging distributed training…

分布式、并行与集群计算 · 计算机科学 2021-08-17 Weiming Zhuang , Yonggang Wen , Shuai Zhang

As deep neural networks are increasingly being deployed in practice, their efficiency has become an important issue. While there are compression techniques for reducing the network's size, energy consumption and computational requirement,…

机器学习 · 计算机科学 2020-01-31 Brandon Paulsen , Jingbo Wang , Chao Wang

In recent years, Diffusion Models have become the new state-of-the-art in deep generative modeling, ending the long-time dominance of Generative Adversarial Networks. Inspired by the Regularization by Denoising principle, we introduce an…

图像与视频处理 · 电气工程与系统科学 2025-03-31 Pasquale Cascarano , Lorenzo Stacchio , Andrea Sebastiani , Alessandro Benfenati , Ulugbek S. Kamilov , Gustavo Marfia

This paper presents DetailFlow, a coarse-to-fine 1D autoregressive (AR) image generation method that models images through a novel next-detail prediction strategy. By learning a resolution-aware token sequence supervised with progressively…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Yiheng Liu , Liao Qu , Huichao Zhang , Xu Wang , Yi Jiang , Yiming Gao , Hu Ye , Xian Li , Shuai Wang , Daniel K. Du , Fangmin Chen , Zehuan Yuan , Xinglong Wu

Deep ensemble methods often improve predictive performance, yet they suffer from three practical limitations: redundancy among base models that inflates computational cost and degrades conditioning, unstable weighting under…

机器学习 · 计算机科学 2026-04-27 Noor Islam S. Mohammad , Md Muntaqim Meherab

New technologies such as Rectified Flow and Flow Matching have significantly improved the performance of generative models in the past two years, especially in terms of control accuracy, generation quality, and generation efficiency.…

计算机视觉与模式识别 · 计算机科学 2026-01-09 Sen Fang , Hongbin Zhong , Yalin Feng , Yanxin Zhang , Dimitris N. Metaxas

In additive manufacturing (AM), particularly for laser-based metal AM, process optimization is crucial to the quality of products and the efficiency of production. The identification of optimal process parameters out of a vast parameter…

材料科学 · 物理学 2024-07-25 Xiao Shang , Evelyn Li , Ajay Talbot , Haitao Wen , Tianyi Lyu , Jiahui Zhang , Yu Zou