相关论文: SpecMER: Fast Protein Generation with K-mer Guided…

Speculative decoding, which combines a draft model with a target model, has emerged as an effective approach to accelerate large language model (LLM) inference. However, existing methods often face a trade-off between the acceptance rate…

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

Speculative decoding has been shown as an effective way to accelerate Large Language Model (LLM) inference by using a Small Speculative Model (SSM) to generate candidate tokens in a so-called speculation phase, which are subsequently…

Designing protein sequences with desired biological function is crucial in biology and chemistry. Recent machine learning methods use a surrogate sequence-function model to replace the expensive wet-lab validation. How can we efficiently…

Test-time scaling has emerged as a powerful paradigm for enhancing the reasoning capabilities of large language models (LLMs) by allocating additional computational resources during inference. However, this paradigm is inherently…

Designing DNA and protein sequences with improved function has the potential to greatly accelerate synthetic biology. Machine learning models that accurately predict biological fitness from sequence are becoming a powerful tool for…

The past few years have witnessed a growing interest in LLM-based recommender systems (RSs), although their industrial deployment remains in a preliminary stage. Most existing deployments leverage LLMs offline as feature enhancers,…

De novo design of molecules has recently enjoyed the power of generative deep neural networks. Current approaches aim to generate molecules either resembling the properties of the molecules of the training set or molecules that are…

Proteins move and deform to ensure their biological functions. Despite significant progress in protein structure prediction, approximating conformational ensembles at physiological conditions remains a fundamental open problem. This paper…

Recent works have revealed the great potential of speculative decoding in accelerating the autoregressive generation process of large language models. The success of these methods relies on the alignment between draft candidates and the…

Speculative decoding and quantization effectively accelerate memory-bound inference of large language models. Speculative decoding mitigates the memory bandwidth bottleneck by verifying multiple tokens within a single forward pass, which…

Autoregressive (AR) models have achieved remarkable success in image synthesis, yet their sequential nature imposes significant latency constraints. Speculative Decoding offers a promising avenue for acceleration, but existing approaches…

A specific challenge with deep learning approaches for molecule generation is generating both syntactically valid and chemically plausible molecular string representations. To address this, we propose a novel generative latent-variable…

Proteins are macromolecules that mediate a significant fraction of the cellular processes that underlie life. An important task in bioengineering is designing proteins with specific 3D structures and chemical properties which enable…

Autoregressive (AR) modeling has recently emerged as a promising new paradigm in visual generation, but its practical adoption is severely constrained by the slow inference speed of per-token generation, which often requires thousands of…

Large Language Models (LLMs) have become widely used for Software Engineering (SE) tasks, spanning from function-level code generation to complex repository-level workflows. However, the high latency of autoregressive inference remains a…

Speculative Decoding (SD) ensures that the output matches the target model's distribution exactly. However, we argue that this distribution matching requirement is too stringent and results in unnecessarily low acceptance rates, limiting…

We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein sequencing relies on mass spectrometry, with some novel edman degregation based…

Adeno-associated viral (AAV) vectors are widely used delivery platforms in gene therapy, and the design of improved capsids is key to expanding their therapeutic potential. A central challenge in AAV bioengineering, as in protein design…

We introduce Retrieval-Based Speculative Decoding (REST), a novel algorithm designed to speed up language model generation. The key insight driving the development of REST is the observation that the process of text generation often…