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The interpretation of histopathology cases underlies many important diagnostic and treatment decisions in medicine. Notably, this process typically requires pathologists to integrate and summarize findings across multiple slides per case.…

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

Histologic examination plays a crucial role in oncology research and diagnostics. The adoption of digital scanning of whole slide images (WSI) has created an opportunity to leverage deep learning-based image classification methods to…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Md Zahangir Alom , Quynh T. Tran , Brent A. Orr

This paper addresses complex challenges in histopathological image analysis through three key contributions. Firstly, it introduces a fast patch selection method, FPS, for whole-slide image (WSI) analysis, significantly reducing…

计算机视觉与模式识别 · 计算机科学 2024-03-13 Saghir Alfasly , Abubakr Shafique , Peyman Nejat , Jibran Khan , Areej Alsaafin , Ghazal Alabtah , H. R. Tizhoosh

The development of robust artificial intelligence models for histopathology diagnosis is severely constrained by the scarcity of expert-annotated lesion data, particularly for rare pathologies and underrepresented disease subtypes. While…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Mohamad Koohi-Moghadam , Mohammad-Ali Nikouei Mahani , Kyongtae Tyler Bae

This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

计算机视觉与模式识别 · 计算机科学 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

High-quality whole-slide scanning is expensive, complex, and time-consuming, thus limiting the acquisition and utilization of high-resolution histopathology images in daily clinical work. Deep learning-based single-image super-resolution…

图像与视频处理 · 电气工程与系统科学 2024-11-08 Minghong Duan , Linhao Qu , Zhiwei Yang , Manning Wang , Chenxi Zhang , Zhijian Song

Histopathology serves as the gold standard in cancer diagnosis, with clinical reports being vital in interpreting and understanding this process, guiding cancer treatment and patient care. The automation of histopathology report generation…

计算机视觉与模式识别 · 计算机科学 2024-06-19 Zhengrui Guo , Jiabo Ma , Yingxue Xu , Yihui Wang , Liansheng Wang , Hao Chen

Diagnosing diseases through histopathology whole slide images (WSIs) is fundamental in modern pathology but is challenged by the gigapixel scale and complexity of WSIs. Trained histopathologists overcome this challenge by navigating the…

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

图像与视频处理 · 电气工程与系统科学 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

计算机视觉与模式识别 · 计算机科学 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

Training a deep learning model to classify histopathological images is challenging, because of the color and shape variability of the cells and tissues, and the reduced amount of available data, which does not allow proper learning of those…

计算机视觉与模式识别 · 计算机科学 2023-07-25 Saypraseuth Mounsaveng , Issam Laradji , David Vázquez , Marco Perdersoli , Ismail Ben Ayed

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Noorul Wahab , Nasir Rajpoot

Due to the high cost of annotation or the rarity of some diseases, medical image segmentation is often limited by data scarcity and the resulting overfitting problem. Self-supervised learning and semi-supervised learning can mitigate the…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Danyang Sun , Fadi Dornaika , Nagore Barrena

Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…

计算工程、金融与科学 · 计算机科学 2023-09-14 Yuandou Wang , Neel Kanwal , Kjersti Engan , Chunming Rong , Zhiming Zhao

Histopathology slide digitization introduces scanner-induced domain shift that can significantly impact computational pathology models based on deep learning methods. In the state-of-the-art, this shift is often characterized at a broad…

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