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Medical image understanding requires meticulous examination of fine visual details, with particular regions requiring additional attention. While radiologists build such expertise over years of experience, it is challenging for AI models to…

计算机视觉与模式识别 · 计算机科学 2024-12-09 Ying Jin , Zhuoran Zhou , Haoquan Fang , Jenq-Neng Hwang

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Microscopic assessment of histopathology images is vital for accurate cancer diagnosis and treatment. Whole Slide Image (WSI) classification and captioning have become crucial tasks in computer-aided pathology. However, microscopic WSI face…

计算机视觉与模式识别 · 计算机科学 2025-07-10 S M Taslim Uddin Raju , Md. Milon Islam , Md Rezwanul Haque , Hamdi Altaheri , Fakhri Karray

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

Vision Transformers (ViTs) and their multi-scale and hierarchical variations have been successful at capturing image representations but their use has been generally studied for low-resolution images (e.g. - 256x256, 384384). For gigapixel…

计算机视觉与模式识别 · 计算机科学 2022-06-07 Richard J. Chen , Chengkuan Chen , Yicong Li , Tiffany Y. Chen , Andrew D. Trister , Rahul G. Krishnan , Faisal Mahmood

The last decade has seen significant advances in computer-aided diagnostics for cytological screening, mainly through the improvement and integration of scanning techniques such as whole slide imaging (WSI) and the combination with deep…

信号处理 · 电气工程与系统科学 2026-01-23 Philip Groult , Julia D. Sistermanns , Ellen Emken , Oliver Hayden , Wolfgang Utschick

Computational cytology faces two major challenges: i) instance-level labels are unreliable and prohibitively costly to obtain, ii) witness rates are extremely low. We propose SLAM-AGS, a Slide-Label-Aware Multitask pretraining framework…

计算机视觉与模式识别 · 计算机科学 2026-01-15 Marco Acerbis , Swarnadip Chatterjee , Christophe Avenel , Joakim Lindblad

The integration of AI in digital pathology, particularly in whole slide image (WSI) and spatial transcriptomics (ST) analysis, holds immense potential for enhancing our understanding of diseases. Despite challenges such as training pattern…

定量方法 · 定量生物学 2024-11-18 Chao-Hui Huang , Sara Lichtarge , Diane Fernandez

Data augmentation is essential in medical imaging for improving classification accuracy, lesion detection, and organ segmentation under limited data conditions. However, two significant challenges remain. First, a pronounced domain gap…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Xuyin Qi , Zeyu Zhang , Canxuan Gang , Hao Zhang , Lei Zhang , Zhiwei Zhang , Yang Zhao

Geometric transformations have been widely used to augment the size of training images. Existing methods often assume a unimodal distribution of the underlying transformations between images, which limits their power when data with…

计算机视觉与模式识别 · 计算机科学 2025-03-11 Tonmoy Hossain , Miaomiao Zhang

In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…

Assessing microsatellite stability status of a patient's colorectal cancer is crucial in personalizing treatment regime. Recently, convolutional-neural-networks (CNN) combined with transfer-learning approaches were proposed to circumvent…

计算机视觉与模式识别 · 计算机科学 2022-08-23 Daniel Shats , Hadar Hezi , Guy Shani , Yosef E. Maruvka , Moti Freiman

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via…

计算机视觉与模式识别 · 计算机科学 2025-08-15 Myeongjang Pyeon , Janghyeon Lee , Minsoo Lee , Juseung Yun , Hwanil Choi , Jonghyun Kim , Jiwon Kim , Yi Hu , Jongseong Jang , Soonyoung Lee

Deep learning for histopathology has been successfully used for disease classification, image segmentation and more. However, combining image and text modalities using current state-of-the-art methods has been a challenge due to the high…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Saurav Sengupta , Donald E. Brown

Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply…

计算机视觉与模式识别 · 计算机科学 2025-10-29 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Kai Zhang , Zhongyi Shui , Bowen Ding , Tao Lin , Lin Yang

Machine learning in computational pathology (CPath) often aggregates patch-level predictions from multi-gigapixel Whole Slide Images (WSIs) to generate WSI-level prediction scores for crucial tasks such as survival prediction and drug…

机器学习 · 计算机科学 2025-12-29 Piotr Keller , Muhammad Dawood , Brinder Singh Chohan , Fayyaz ul Amir Afsar Minhas

Data Augmentation (DA) is a technique to increase the quantity and diversity of the training data, and by that alleviate overfitting and improve generalisation. However, standard DA produces synthetic data for augmentation with limited…

计算机视觉与模式识别 · 计算机科学 2023-07-24 Lorenzo Tronchin , Minh H. Vu , Paolo Soda , Tommy Löfstedt

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel