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Motivated by diverse phenomena in cellular biophysics, including bacterial flagellar motion and DNA transcription and replication, we study the overdamped nonlinear dynamics of a rotationally forced filament with twist and bend elasticity.…

软凝聚态物质 · 物理学 2009-10-31 Charles W. Wolgemuth , Thomas R. Powers , Raymond E. Goldstein

Active stresses can cause instabilities in contractile gels and living tissues. Here we describe a generic hydrodynamic theory that treats these systems as a mixture of two phases of varying activity and different mechanical properties. We…

生物物理 · 物理学 2018-06-20 Christoph Weber , Chris H. Rycroft , L. Mahadevan

The dynamics of geometrically non-linear flexible filaments play an important role in a host of biological processes, from flagella-driven cell transport to the polymeric structure of complex fluids. Such problems have historically been…

We study the fully-coupled dynamics between a fully-developed turbulent flow and an ensemble of immersed flexible fibers. We vary the concentration of the suspension, the mechanical properties and the length of the fibers in a vast…

流体动力学 · 物理学 2021-08-24 Stefano Olivieri , Andrea Mazzino , Marco E. Rosti

The articulation process of dynamical networks is studied with a functional map, a minimal model for the dynamic change of relationships through iteration. The model is a dynamical system of a function $f$, not of variables, having a…

adap-org · 物理学 2009-10-31 N. Kataoka , K. Kaneko

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

组织与器官 · 定量生物学 2023-03-08 Nen Saito , Shuji Ishihara

Active deformable filaments exhibit a large range of qualitatively different three-dimensional dynamics, depending on their flexibility, the strength and nature of the active forcing, and the surrounding environment. We investigate the…

流体动力学 · 物理学 2025-10-14 Matthew D Butler , Benjamin J Walker , Thomas Montenegro-Johnson , Panayiota Katsamba

In this paper, we develop and analyze a minimal model for a 2D network of cross-linked actin filaments and myosin motors, representing the cortical cytoskeleton of eukaryotic cells. We implement coarse-grained representations of force…

亚细胞过程 · 定量生物学 2016-12-23 William M. McFadden , Patrick M. McCall , Edwin M. Munro

We explore the impact of hydrodynamic interactions on the conformational and dynamical properties of wet tangentially-driven active polymers using multiparticle collision dynamics simulations. By analyzing active filaments with varying…

软凝聚态物质 · 物理学 2024-10-24 Loek van Steijn , Mohammad Fazelzadeh , Sara Jabbari-Farouji

Flagella and cilia are examples of actively oscillating, whiplike biological filaments that are crucial to processes as diverse as locomotion, mucus clearance, embryogenesis and cell motility. Elastic driven rod-like filaments subjected to…

计算物理 · 物理学 2018-05-24 Soheil Fatehiboroujeni , Arvind Gopinath , Sachin Goyal

Experimental studies of systems containing active proteins that undergo conformational changes driven by catalytic chemical reactions have shown that the diffusion coefficients of passive tracer particles and active molecules are larger…

软凝聚态物质 · 物理学 2017-02-27 Matthew Dennison , Raymond Kapral , Holger Stark

We study the segregation of motile semiflexible filaments from a background of similar but non-motile filaments. Our Langevin dynamics simulations reveal a wide range of emergent structures governed by filament flexibility and activity,…

软凝聚态物质 · 物理学 2025-12-22 Chitrak Bhowmik , Aparna Baskaran , Sriram Ramaswamy

During the spreading of epithelial tissues, the advancing tissue front often develops fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven fluids suggests that epithelial fingers could arise from an…

生物物理 · 物理学 2019-03-05 Ricard Alert , Carles Blanch-Mercader , Jaume Casademunt

The spontaneous creation of disclinations is a defining characteristic of active nematics, which is rarely observed in equilibrium systems or other active matter systems. Thus, understanding the mechanics of disclinations is crucial for…

软凝聚态物质 · 物理学 2025-07-01 Yingyou Ma , Christopher Amey , Aparna Baskaran , Michael F. Hagan

The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions. We…

软凝聚态物质 · 物理学 2020-05-28 Guanming Zhang , Romain Mueller , Amin Doostmohammadi , Julia M. Yeomans

The dynamics of a stiff filament (made by connecting beads) embedded in size-polydisperse hard sphere fluid is investigated by means of molecular dynamics simulations with focus on how the degree of size-polydispersity, characterized by…

软凝聚态物质 · 物理学 2025-03-06 Thokchom Premkumar Meitei , Lenin S. Shagolsem

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

生物物理 · 物理学 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

Biological tissues are active materials whose non-equilibrium dynamics emerge from distinct cellular force-generating mechanisms. Using a two-dimensional active foam model, we compare the effects of traction forces and junctional tension…

生物物理 · 物理学 2026-04-14 Alessandro Rizzi , Sangwoo Kim

We examine theoretically the flow interactions and forward flight dynamics of tandem or in-line flapping wings. Two wings are driven vertically with prescribed heaving-and-plunging motions, and the horizontal propulsion speeds and positions…

流体动力学 · 物理学 2026-05-13 Fang Fang , Christiana Mavroyiakoumou , Leif Ristroph , Michael J. Shelley

Models based on surfactant driven instabilities have been employed to describe pattern formation by swarming bacteria. However, by definition, such models cannot account for the effect of bacterial sensing and decision making. Here we…