相关论文: Abundance-Aware Set Transformer for Microbiome Sam…

Many modern biological assays, including RNA sequencing, yield integer-valued counts that reflect the number of molecules detected. These measurements are often not at the desired resolution: while the unit of interest is typically a single…

Data mixing methods play a crucial role in semi-supervised learning (SSL), but their application is unexplored in long-tailed semi-supervised learning (LTSSL). The primary reason is that the in-batch mixing manner fails to address class…

In this paper, we show that the performance of a learnt generative model is closely related to the model's ability to accurately represent the inferred \textbf{latent data distribution}, i.e. its topology and structural properties. We…

To synthesize high-fidelity samples, diffusion models typically require auxiliary data to guide the generation process. However, it is impractical to procure the painstaking patch-level annotation effort required in specialized domains like…

We present the Insertion Transformer, an iterative, partially autoregressive model for sequence generation based on insertion operations. Unlike typical autoregressive models which rely on a fixed, often left-to-right ordering of the…

A key obstacle in automated analytics and meta-learning is the inability to recognize when different datasets contain measurements of the same variable. Because provided attribute labels are often uninformative in practice, this task may be…

Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

Analyzing the morphology of cells in microscopy images can provide insights into the mechanism of compounds or the function of genes. Addressing this task requires methods that can not only extract biological information from the images,…

Large language models (LLMs) call for extension of context to handle many critical applications. However, the existing approaches are prone to expensive costs and inferior quality of context extension. In this work, we proposeExtensible…

Biological sequence analysis relies on the ability to denoise the imprecise output of sequencing platforms. We consider a common setting where a short sequence is read out repeatedly using a high-throughput long-read platform to generate…

High-quality data accumulation is now becoming ubiquitous in the health domain. There is increasing opportunity to exploit rich data from normal subjects to improve supervised estimators in specific diseases with notorious data scarcity. We…

Metagenomics sequencing is routinely applied to quantify bacterial abundances in microbiome studies, where the bacterial composition is estimated based on the sequencing read counts. Due to limited sequencing depth and DNA dropouts, many…

Large language models (LLMs) have shown strong ability in generating rich representations across domains such as natural language processing and generation, computer vision, and multimodal learning. However, their application in biomedical…

Model editing techniques are essential for efficiently updating knowledge in large language models (LLMs). However, the effectiveness of existing approaches degrades in massive editing scenarios, particularly when evaluated with practical…

Sequence feature embedding is a challenging task due to the unstructuredness of sequence, i.e., arbitrary strings of arbitrary length. Existing methods are efficient in extracting short-term dependencies but typically suffer from…

Pretrained encoders for mathematical texts have achieved significant improvements on various tasks such as formula classification and information retrieval. Yet they remain limited in representing and capturing student strategies for entire…

The task of learning to map an input set onto a permuted sequence of its elements is challenging for neural networks. Set-to-sequence problems occur in natural language processing, computer vision and structure prediction, where…

Selecting high-quality and diverse training samples from extensive datasets plays a crucial role in reducing training overhead and enhancing the performance of Large Language Models (LLMs). However, existing studies fall short in assessing…

Scanning Electron Microscopy (SEM) is indispensable in modern materials science, enabling high-resolution imaging across a wide range of structural, chemical, and functional investigations. However, SEM imaging remains constrained by…

This paper presents a novel methodology for generating realistic abundance maps from hyperspectral imagery using an unsupervised, deep-learning-driven approach. Our framework integrates blind linear hyperspectral unmixing with…