相关论文: Priority-Aware Clinical Pathology Hierarchy Traini…

Scheduling problems requires to explicitly account for control considerations in their optimisation. The literature proposes two traditional ways to solve this integrated problem: hierarchical and monolithic. The monolithic approach ignores…

In this paper, we address the Multi-Instance-Learning (MIL) problem when bag labels are naturally represented as ordinal variables (Multi--Instance--Ordinal Regression). Moreover, we consider the case where bags are temporal sequences of…

Class incremental learning (CIL) algorithms aim to continually learn new object classes from incrementally arriving data while not forgetting past learned classes. The common evaluation protocol for CIL algorithms is to measure the average…

Multi-view learning (MVL) has gained great success in integrating information from multiple perspectives of a dataset to improve downstream task performance. To make MVL methods more practical in an open-ended environment, this paper…

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Multiple Instance Learning (MIL) models have proven effective for cancer prognosis from Whole Slide Images. However, the original MIL formulation incorrectly assumes the patches of the same image to be independent, leading to a loss of…

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Class-Incremental Learning (CIL) trains a model to continually recognize new classes from non-stationary data while retaining learned knowledge. A major challenge of CIL arises when applying to real-world data characterized by non-uniform…

Expression of human epidermal growth factor receptor 2 (HER2) is an important biomarker in breast cancer patients who can benefit from cost-effective automatic Hematoxylin and Eosin (H\&E) HER2 scoring. However, developing such scoring…

In deep multi-instance learning, the number of applicable instances depends on the data set. In histopathology images, deep learning multi-instance learners usually assume there are hundreds to thousands instances in a bag. However, when…

In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…

Multiple Instance Learning (MIL) tasks impose a strict logical constraint: a bag is labeled positive if and only if at least one instance within it is positive. While this iff constraint aligns with many real-world applications, recent work…

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…