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Histopathological assessments, including surgical resection and core needle biopsy, are the standard procedures in the diagnosis of the prostate cancer. Current interpretation of the histopathology images includes the determination of the…

计算机视觉与模式识别 · 计算机科学 2017-05-12 Naiyun Zhou , Andrey Fedorov , Fiona Fennessy , Ron Kikinis , Yi Gao

Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…

计算机视觉与模式识别 · 计算机科学 2024-07-30 Honglin Li , Yusuan Sun , Chenglu Zhu , Yunlong Zhang , Shichuan Zhang , Zhongyi Shui , Pingyi Chen , Jingxiong Li , Sunyi Zheng , Can Cui , Lin Yang

We present an innovative method for rapidly segmenting hematoxylin and eosin (H&E)-stained tissue in whole-slide images (WSIs) that eliminates a wide range of undesirable artefacts such as pen marks and scanning artefacts. Our method…

图像与视频处理 · 电气工程与系统科学 2023-12-20 B. A. Schreiber , J. Denholm , F. Jaeckle , M. J. Arends , K. M. Branson , C. -B. Schönlieb , E. J. Soilleux

Consecutive thin sections of tissue samples make it possible to study local variation in e.g. protein expression and tumor heterogeneity by staining for a new protein in each section. In order to compare and correlate patterns of different…

计算机视觉与模式识别 · 计算机科学 2019-01-25 Leslie Solorzano , Gabriela M. Almeida , Bárbara Mesquita , Diana Martins , Carla Oliveira , Carolina Wählby

Large-scale pre-training models have promoted the development of histopathology image analysis. However, existing self-supervised methods for histopathology images primarily focus on learning patch features, while there is a notable gap in…

计算机视觉与模式识别 · 计算机科学 2024-12-09 Kun Wu , Zhiguo Jiang , Kunming Tang , Jun Shi , Fengying Xie , Wei Wang , Haibo Wu , Yushan Zheng

This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

计算机视觉与模式识别 · 计算机科学 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

计算机视觉与模式识别 · 计算机科学 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

Whole slide imaging (WSI) has recently been cleared for primary diagnosis in the US. A critical challenge of WSI is to perform accurate focusing in high speed. Traditional systems create a focus map prior to scanning. For each focus point…

计算机视觉与模式识别 · 计算机科学 2019-04-26 Jun Liao , Yutong Jiang , Zichao Bian , Bahareh Mahrou , Aparna Nambiar , Alexander W. Magsam , Kaikai Guo , Yong Ku Cho , Guoan Zheng

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any…

图像与视频处理 · 电气工程与系统科学 2023-10-20 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nishant Ravikumar , Nicolas M. Orsi

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

图像与视频处理 · 电气工程与系统科学 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

计算机视觉与模式识别 · 计算机科学 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

We study the attention of pathologists as they examine whole-slide images (WSIs) of prostate cancer tissue using a digital microscope. To the best of our knowledge, our study is the first to report in detail how pathologists navigate WSIs…

图像与视频处理 · 电气工程与系统科学 2022-05-04 Souradeep Chakraborty , Ke Ma , Rajarsi Gupta , Beatrice Knudsen , Gregory J. Zelinsky , Joel H. Saltz , Dimitris Samaras

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

计算机视觉与模式识别 · 计算机科学 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

计算机视觉与模式识别 · 计算机科学 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

计算机视觉与模式识别 · 计算机科学 2026-03-24 So Won Jeong , Veronika Ročková

Asthma is a chronic inflammatory disorder of the lower respiratory tract and naturally occurs in humans and animals including horses. The annotation of an asthma microscopy whole slide image (WSI) is an extremely labour-intensive task due…

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang