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Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

The ThinPrep Cytologic Test (TCT) is the most widely used method for cervical cancer screening, and the sample quality directly impacts the accuracy of the diagnosis. Traditional manual evaluation methods rely on the observation of…

图像与视频处理 · 电气工程与系统科学 2025-05-21 Lanlan Kang , Jian Wang , Jian QIn , Yiqin Liang , Yongjun He

High-throughput "pathomic" analysis of Whole Slide Images (WSIs) offers new opportunities to study tissue characteristics and for biomarker discovery. However, the clinical relevance of the tissue characteristics at the micro- and…

计算机视觉与模式识别 · 计算机科学 2025-12-24 Yuechen Yang , Junlin Guo , Yanfan Zhu , Jialin Yue , Junchao Zhu , Yu Wang , Shilin Zhao , Haichun Yang , Xingyi Guo , Jovan Tanevski , Laura Barisoni , Avi Z. Rosenberg , Yuankai Huo

Machine learning in computational pathology (CPath) often aggregates patch-level predictions from multi-gigapixel Whole Slide Images (WSIs) to generate WSI-level prediction scores for crucial tasks such as survival prediction and drug…

机器学习 · 计算机科学 2025-12-29 Piotr Keller , Muhammad Dawood , Brinder Singh Chohan , Fayyaz ul Amir Afsar Minhas

The analysis of FFPE tissue sections stained with haematoxylin and eosin (H&E) or immunohistochemistry (IHC) is an essential part of the pathologic assessment of surgically resected breast cancer specimens. IHC staining has been broadly…

Traditionally, pathological analysis and diagnosis are performed by manually eyeballing glass slide specimens under a microscope by an expert. The whole slide image is the digital specimen produced from the glass slide. Whole slide image…

图像与视频处理 · 电气工程与系统科学 2024-03-14 Galib Muhammad Shahriar Himel

Image based biomarker discovery typically requires an accurate segmentation of histologic structures (e.g., cell nuclei, tubules, epithelial regions) in digital pathology Whole Slide Images (WSI). Unfortunately, annotating each structure of…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Runtian Miao , Robert Toth , Yu Zhou , Anant Madabhushi , Andrew Janowczyk

Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

图像与视频处理 · 电气工程与系统科学 2020-07-07 Rui Aguiar , Jon Braatz

Automatic detection of cancer metastasis from whole slide images (WSIs) is a crucial step for following patient staging and prognosis. Recent convolutional neural network based approaches are struggling with the trade-off between accuracy…

计算机视觉与模式识别 · 计算机科学 2019-07-16 Zixu Zhao , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

图像与视频处理 · 电气工程与系统科学 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Diffusion-weighted imaging (DWI) can support lesion detection and characterization in breast magnetic resonance imaging (MRI), however especially high b-value diffusion-weighted acquisitions can be prone to intensity artifacts that can…

Hematoxylin- and eosin (H&E) stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-based methods in computational pathology enabled the prediction of biomarkers directly…

During the last decade, the digitization of pathology has gained considerable momentum. Digital pathology offers many advantages including more efficient workflows, easier collaboration as well as a powerful venue for telepathology. At the…

图像与视频处理 · 电气工程与系统科学 2020-06-12 Abtin Riasatian , Maral Rasoolijaberi , Morteza Babaei , H. R. Tizhoosh

Diagnostic, prognostic and therapeutic decision-making of cancer in pathology clinics can now be carried out based on analysis of multi-gigapixel tissue images, also known as whole-slide images (WSIs). Recently, deep convolutional neural…

图像与视频处理 · 电气工程与系统科学 2022-09-08 Quoc Dang Vu , Kashif Rajpoot , Shan E Ahmed Raza , Nasir Rajpoot

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

计算机视觉与模式识别 · 计算机科学 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy…

Automated whole slide image (WSI) tagging has become a growing demand due to the increasing volume and diversity of WSIs collected nowadays in histopathology. Various methods have been studied to classify WSIs with single tags but none of…

计算机视觉与模式识别 · 计算机科学 2019-07-05 Weijian Li , Viet-Duy Nguyen , Haofu Liao , Matt Wilder , Ke Cheng , Jiebo Luo