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Within epidemiological modeling, the majority of analyses assume a single epidemic process for generating ground-truth data. However, this assumed data generation process can be unrealistic, since data sources for epidemics are often…

人工智能 · 计算机科学 2021-06-22 Anna L. Trella , Peniel N. Argaw , Michelle M. Li , James A. Hay

Approximate Bayesian Computation (ABC) methods have become essential tools for performing inference when likelihood functions are intractable or computationally prohibitive. However, their scalability remains a major challenge in…

统计方法学 · 统计学 2025-07-09 Antoine Luciano , Charly Andral , Christian P. Robert , Robin J. Ryder

Individual-level models, also known as ILMs, are commonly used in epidemics modelling, as they can flexibly incorporate individual-level covariates that influence susceptibility and transmissibility upon infection. However, inference for…

统计方法学 · 统计学 2025-09-08 Yirao Zhang , Rob Deardon , Lorna Deeth

In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

应用统计 · 统计学 2011-11-10 Marcos A. Capistrán , J. Andrés Christen , Jorge X. Velasco-Hernández

The aim of this short note is twofold. We formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key…

种群与进化 · 定量生物学 2023-08-01 M. C. J. Bootsma , K. M. D. Chan , O. Diekmann , H. Inaba

The potential effects of conservation actions on threatened species can be predicted using ensemble ecosystem models by forecasting populations with and without intervention. These model ensembles commonly assume stable coexistence of…

种群与进化 · 定量生物学 2024-03-22 Sarah A. Vollert , Christopher Drovandi , Matthew P. Adams

Mathematical models of epidemic dynamics offer significant insight into predicting and controlling infectious diseases. The dynamics of a disease model generally follow a susceptible, infected, and recovered (SIR) model, with some standard…

种群与进化 · 定量生物学 2013-11-28 Caitlyn Witkowski , Brian Blais

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

计量经济学 · 经济学 2023-02-01 Cem Cakmakli , Yasin Simsek

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

种群与进化 · 定量生物学 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

Epidemic models are useful tools in the fight against infectious diseases, as they allow policy makers to test and compare various strategies to limit disease transmission while mitigating collateral damage on the economy. Epidemic models…

种群与进化 · 定量生物学 2021-08-18 Joseph D. Peterson , Ronojoy Adhikari

The effect of public health interventions on an epidemic are often estimated by adding the intervention to epidemic models. During the Covid-19 epidemic, numerous papers used such methods for making scenario predictions. The majority of…

统计方法学 · 统计学 2024-10-16 Heejong Bong , Valérie Ventura , Larry Wasserman

Infectious diseases have severe health and economic consequences for society. It is important in controlling the spread of an emerging infectious disease to be able to both estimate the parameters of the underlying model and identify those…

统计计算 · 统计学 2019-09-26 Jessica Welding , Peter Neal

This document is the Part IV of the book 'Stochastic Epidemic Models with Inference' edited by Tom Britton and Etienne Pardoux. It is written by Catherine Lar\'edo, with the contribution of Viet Chi Tran for the Chapter 4. Epidemic data…

概率论 · 数学 2020-04-17 Catherine Larédo , Viet Chi Tran

This two-part paper presents a new approach to predictive analysis for social processes. In Part I, we begin by identifying a class of social processes which are simultaneously important in applications and difficult to predict using…

适应与自组织系统 · 物理学 2016-11-17 Richard Colbaugh , Kristin Glass

We show how to speed up Sequential Monte Carlo (SMC) for Bayesian inference in large data problems by data subsampling. SMC sequentially updates a cloud of particles through a sequence of distributions, beginning with a distribution that is…

统计计算 · 统计学 2020-03-25 David Gunawan , Khue-Dung Dang , Matias Quiroz , Robert Kohn , Minh-Ngoc Tran

Ensemble forecasts have become a cornerstone of large-scale disease response, underpinning decision making at agencies such as the US Centers for Disease Control and Prevention (CDC). Their growing use reflects the goal of combining…

应用统计 · 统计学 2026-01-23 Carson Dudley , Marisa Eisenberg

We study sequential Bayesian inference in stochastic kinetic models with latent factors. Assuming continuous observation of all the reactions, our focus is on joint inference of the unknown reaction rates and the dynamic latent states,…

统计计算 · 统计学 2014-09-10 Junjing Lin , Michael Ludkovski

Epilepsy is a neurological disorder characterized by recurrent seizures affecting more than 70 million people worldwide. Often, an individual with epilepsy is more likely to experience subsequent seizures following an initial seizure, a…

统计方法学 · 统计学 2026-05-22 Karen Kanaster , Giovani L. Silva , Peter Mueller , Jacob Pellinen , Elizabeth Juarez-Colunga

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

应用统计 · 统计学 2020-03-16 Johannes Bracher , Leonhard Held

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

社会与信息网络 · 计算机科学 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling