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相关论文: A Robust Local Fr\'echet Regression Using Unbalanc…

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Deploying off-the-shelf segmentation networks on biomedical data has become common practice, yet if structures of interest in an image sequence are visible only temporarily, existing frame-by-frame methods fail. In this paper, we provide a…

计算机视觉与模式识别 · 计算机科学 2020-11-23 Özgün Çiçek , Yassine Marrakchi , Enoch Boasiako Antwi , Barbara Di Ventura , Thomas Brox

Motivation: Single cell RNA sequencing (scRNA-seq) data makes studying the development of cells possible at unparalleled resolution. Given that many cellular differentiation processes are hierarchical, their scRNA-seq data is expected to be…

Single-cell RNA sequencing (scRNA-seq) enables dissecting cellular heterogeneity in tissues, resulting in numerous biological discoveries. Various computational methods have been devised to delineate cell types by clustering scRNA-seq data…

定量方法 · 定量生物学 2023-09-18 Tram Huynh , Zixuan Cang

This paper studies the distributed optimization problem with possibly nonidentical local constraints, where its global objective function is composed of $N$ convex functions. The aim is to solve the considered optimization problem in a…

最优化与控制 · 数学 2022-08-26 Hongzhe Liu , Wenwu Yu , Guanghui Wen , Wei Xing Zheng

Applications such as unbalanced and fully shuffled regression can be approached by optimizing regularized optimal transport (OT) distances, such as the entropic OT and Sinkhorn distances. A common approach for this optimization is to use a…

数值分析 · 数学 2024-10-22 Xingjie Li , Fei Lu , Molei Tao , Felix X. -F. Ye

Distributional robustness is a promising framework for training deep learning models that are less vulnerable to adversarial examples and data distribution shifts. Previous works have mainly focused on exploiting distributional robustness…

机器学习 · 计算机科学 2023-11-02 Van-Anh Nguyen , Trung Le , Anh Tuan Bui , Thanh-Toan Do , Dinh Phung

Single-cell RNA-seq data analysis typically requires representations that capture heterogeneous local structure across multiple scales while remaining stable and interpretable. In this work, we propose a hierarchical sheaf spectral…

机器学习 · 计算机科学 2026-03-31 Xiang Xiang Wang , Guo-Wei We

Distributionally robust supervised learning (DRSL) is emerging as a key paradigm for building reliable machine learning systems for real-world applications -- reflecting the need for classifiers and predictive models that are robust to the…

机器学习 · 计算机科学 2022-01-26 Yaodong Yu , Tianyi Lin , Eric Mazumdar , Michael I. Jordan

Investigations of natural variation among cells within a population are essential for understanding the stochastic nature of tissue cell deformation under applied load. In the existing literature, the population variation of single-cell…

细胞行为 · 定量生物学 2011-07-14 John M. Maloney , Krystyn J. Van Vliet

The concept of mobility prediction represents one of the key enablers for an efficient management of future cellular networks, which tend to be progressively more elaborate and dense due to the aggregation of multiple technologies. In this…

信号处理 · 电气工程与系统科学 2019-07-26 Giulio Siracusano , Aurelio La Corte

We consider distributed convex optimization problems originated from sample average approximation of stochastic optimization, or empirical risk minimization in machine learning. We assume that each machine in the distributed computing…

最优化与控制 · 数学 2015-01-05 Yuchen Zhang , Lin Xiao

Distribution data refers to a data set where each sample is represented as a probability distribution, a subject area receiving burgeoning interest in the field of statistics. Although several studies have developed…

统计方法学 · 统计学 2024-02-09 Ryo Okano , Masaaki Imaizumi

We study distributed optimization algorithms for minimizing the average of \emph{heterogeneous} functions distributed across several machines with a focus on communication efficiency. In such settings, naively using the classical stochastic…

机器学习 · 计算机科学 2020-11-18 Ilqar Ramazanli , Han Nguyen , Hai Pham , Sashank J. Reddi , Barnabas Poczos

The recent proliferation of Data Grids and the increasingly common practice of using resources as distributed data stores provide a convenient environment for communities of researchers to share, replicate, and manage access to copies of…

分布式、并行与集群计算 · 计算机科学 2007-05-23 Sudharshan Vazhkudai , Jennifer M. Schopf

RNA sequencing (RNA-seq) is the conventional genome-scale approach used to capture the expression levels of all detectable genes in a biological sample. This is now regularly used for population-based studies designed to identify genetic…

基因组学 · 定量生物学 2026-05-25 Christopher Thron , Farhad Jafari

By imitating the synaptic connectivity and plasticity of the brain, emerging electronic nanodevices offer new opportunities as the building blocks of neuromorphic systems. One challenge for largescale simulations of computational…

神经与进化计算 · 计算机科学 2022-05-11 T. Hennen , A. Elias , J. F. Nodin , G. Molas , R. Waser , D. J. Wouters , D. Bedau

With the advance of experimental techniques such as time-lapse fluorescence microscopy, the availability of single-cell trajectory data has vastly increased, and so has the demand for computational methods suitable for parameter inference…

定量方法 · 定量生物学 2016-07-06 Irena Kuzmanovska , Andreas Milias-Argeitis , Christoph Zechner , Mustafa Khammash

Fr\'echet regression extends classical regression methods to non-Euclidean metric spaces, enabling the analysis of data relationships on complex structures such as manifolds and graphs. This work establishes a rigorous theoretical analysis…

机器学习 · 统计学 2025-02-05 Masanari Kimura , Howard Bondell

This paper presents a novel methodology for tractably solving optimal control and offline reinforcement learning problems for high-dimensional systems. This work is motivated by the ongoing challenges of safety, computation, and optimality…

最优化与控制 · 数学 2022-07-06 Aaron Kandel , Saehong Park , Scott Moura

Distribution-on-distribution regression considers the problem of formulating and estimating a regression relationship where both covariate and response are probability distributions. The optimal transport distributional regression model…

统计理论 · 数学 2022-06-06 Laya Ghodrati , Victor M. Panaretos