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Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

Pathologically altered iron levels, detected using iron-sensitive MRI techniques such as quantitative susceptibility mapping (QSM), are observed in neurological disorders such as multiple sclerosis (MS) and may play a crucial role in…

Deep learning techniques have demonstrated great potential for accurately estimating brain age by analyzing Magnetic Resonance Imaging (MRI) data from healthy individuals. However, current methods for brain age estimation often directly…

计算机视觉与模式识别 · 计算机科学 2024-09-24 Fanzhe Yan , Gang Yang , Yu Li , Aiping Liu , Xun Chen

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

机器学习 · 计算机科学 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

神经元与认知 · 定量生物学 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

In neuroimaging analysis, fMRI can well assess the function changes for brain diseases with no obvious structural lesions. To date, most deep-learning-based fMRI studies have employed functional connectivity (FC) as the basic feature for…

图像与视频处理 · 电气工程与系统科学 2023-03-03 Wei Dai , Ziyao Zhang , Lixia Tian , Shengyuan Yu , Shuhui Wang , Zhao Dong , Hairong Zheng

Predicting disease states from functional brain connectivity is critical for the early diagnosis of severe neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease. Existing studies commonly employ Graph Neural…

机器学习 · 计算机科学 2025-04-22 David Yang , Mostafa Abdelmegeed , John Modl , Minjeong Kim

Several works based on Generative Adversarial Networks (GAN) have been recently proposed to predict a set of medical images from a single modality (e.g, FLAIR MRI from T1 MRI). However, such frameworks are primarily designed to operate on…

机器学习 · 计算机科学 2020-09-24 Alaa Bessadok , Mohamed Ali Mahjoub , Islem Rekik

Functional connectivity network (FCN) data from functional magnetic resonance imaging (fMRI) is increasingly used for the diagnoses of brain disorders. However, state-of-the-art studies used to build the FCN using a single brain…

图像与视频处理 · 电气工程与系统科学 2022-09-26 Mianxin Liu , Han Zhang , Feng Shi , Dinggang Shen

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

图像与视频处理 · 电气工程与系统科学 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions…

计算机视觉与模式识别 · 计算机科学 2025-08-26 Xuhao Shan , Ruiquan Ge , Jikui Liu , Linglong Wu , Chi Zhang , Siqi Liu , Wenjian Qin , Wenwen Min , Ahmed Elazab , Changmiao Wang

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

机器学习 · 计算机科学 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Multimodal magnetic resonance imaging (MRI) is crucial for brain tumor segmentation, with many methods leveraging its four key modalities to capture complementary information for effective sub-region analysis. However, the absence of…

人工智能 · 计算机科学 2026-05-19 Sha Tao , Jiao Pan , Yu Guo , Chao Yao

Alzheimer's Disease (AD) is the most widespread neurodegenerative disease, affecting over 50 million people across the world. While its progression cannot be stopped, early and accurate diagnostic testing can drastically improve quality of…

机器学习 · 计算机科学 2021-01-11 Vishnu Ram Sampathkumar

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

机器学习 · 计算机科学 2025-03-20 Chenyu Liu , Luca Rossi

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

应用统计 · 统计学 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

Under the framework of network-based neurodegeneration, brain functional connectome (FC)-based Graph Neural Networks (GNN) have emerged as a valuable tool for the diagnosis and prognosis of neurodegenerative diseases such as Alzheimer's…

神经元与认知 · 定量生物学 2023-07-14 Zijian Dong , Yilei Wu , Yu Xiao , Joanna Su Xian Chong , Yueming Jin , Juan Helen Zhou

With the advances of data-driven machine learning research, a wide variety of prediction problems have been tackled. It has become critical to explore how machine learning and specifically deep learning methods can be exploited to analyse…

机器学习 · 计算机科学 2021-11-09 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

In this study, we proposed and evaluated a graph-based framework to assess variations in Alzheimer's disease (AD) neuropathologies, focusing on classic (cAD) and rapid (rpAD) progression forms. Histopathological images are converted into…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Gabriel Jimenez , Leopold Hebert-Stevens , Benoit Delatour , Lev Stimmer , Daniel Racoceanu