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Brain age estimation is clinically important as it can provide valuable information in the context of neurodegenerative diseases such as Alzheimer's. Population graphs, which include multimodal imaging information of the subjects along with…

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Deep models suffer from limited generalization capability to unseen domains, which has severely hindered their clinical applicability. Specifically for the retinal vessel segmentation task, although the model is supposed to learn the…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Dewei Hu , Hao Li , Han Liu , Xing Yao , Jiacheng Wang , Ipek Oguz

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

计算机视觉与模式识别 · 计算机科学 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Biological neural networks define the brain function and intelligence of humans and other mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is closely interconnected with the spatial organization of the…

Graph neural networks (GNNs) have demonstrated success in learning representations of brain graphs derived from functional magnetic resonance imaging (fMRI) data. However, existing GNN methods assume brain graphs are static over time and…

机器学习 · 计算机科学 2023-07-11 Alexander Campbell , Antonio Giuliano Zippo , Luca Passamonti , Nicola Toschi , Pietro Lio

UMAP is a non-parametric graph-based dimensionality reduction algorithm using applied Riemannian geometry and algebraic topology to find low-dimensional embeddings of structured data. The UMAP algorithm consists of two steps: (1) Compute a…

机器学习 · 计算机科学 2021-08-31 Tim Sainburg , Leland McInnes , Timothy Q Gentner

Brain age gap estimation (BrainAGE) is a promising imaging-derived biomarker of neurobiological aging and disease risk, yet current approaches rely predominantly on T1-weighted structural MRI (T1w), overlooking functional vascular changes…

图像与视频处理 · 电气工程与系统科学 2025-12-10 Jordan Jomsky , Kay C. Igwe , Zongyu Li , Yiren Zhang , Max Lashley , Tal Nuriel , Andrew Laine , Jia Guo

We introduce BrainSAIL, a method for linking neural selectivity with spatially distributed semantic visual concepts in natural scenes. BrainSAIL leverages recent advances in large-scale artificial neural networks, using them to provide…

计算机视觉与模式识别 · 计算机科学 2025-06-25 Andrew F. Luo , Jacob Yeung , Rushikesh Zawar , Shaurya Dewan , Margaret M. Henderson , Leila Wehbe , Michael J. Tarr

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Recent studies have made great progress in functional brain network classification by modeling the brain as a network of Regions of Interest (ROIs) and leveraging their connections to understand brain functionality and diagnose mental…

神经元与认知 · 定量生物学 2025-07-22 Jiacheng Hou , Zhenjie Song , Ercan Engin Kuruoglu

Whole-brain parcellation from MRI is a critical yet challenging task due to the complexity of subdividing the brain into numerous small, irregular shaped regions. Traditionally, template-registration methods were used, but recent advances…

计算机视觉与模式识别 · 计算机科学 2026-01-15 Yucheng Li , Xiaofan Wang , Junyi Wang , Yijie Li , Xi Zhu , Mubai Du , Dian Sheng , Wei Zhang , Fan Zhang

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Nonlinear dimensional reduction with the manifold assumption, often called manifold learning, has proven its usefulness in a wide range of high-dimensional data analysis. The significant impact of t-SNE and UMAP has catalyzed intense…

机器学习 · 计算机科学 2026-04-02 Jungeum Kim , Xiao Wang

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

图像与视频处理 · 电气工程与系统科学 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

机器学习 · 计算机科学 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong

Brain tumors result from abnormal cell growth in brain tissue. If undiagnosed, they cause neurological deficits, including cognitive impairment, motor dysfunction, and sensory loss. As tumors grow, intracranial pressure increases,…

图像与视频处理 · 电气工程与系统科学 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Aravintakshan S A , Pavan Kumar S , Kannan A , Madhan S

Graph Transformer shows remarkable potential in brain network analysis due to its ability to model graph structures and complex node relationships. Most existing methods typically model the brain as a flat network, ignoring its modular…

机器学习 · 计算机科学 2025-11-25 Jiajun Ma , Yongchao Zhang , Chao Zhang , Zhao Lv , Shengbing Pei

Network analysis of human brain connectivity is critically important for understanding brain function and disease states. Embedding a brain network as a whole graph instance into a meaningful low-dimensional representation can be used to…

机器学习 · 计算机科学 2018-07-26 Ye Liu , Lifang He , Bokai Cao , Philip S. Yu , Ann B. Ragin , Alex D. Leow