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Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

机器学习 · 计算机科学 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…

机器学习 · 计算机科学 2024-07-29 Asim Waqas , Aakash Tripathi , Ravi P. Ramachandran , Paul Stewart , Ghulam Rasool

Graphs provide a powerful means for representing complex interactions between entities. Recently, deep learning approaches are emerging for representing and modeling graph-structured data, although the conventional deep learning methods…

神经与进化计算 · 计算机科学 2016-12-06 Jaekoo Lee , Hyunjae Kim , Jongsun Lee , Sungroh Yoon

Motivation: Cancer is heterogeneous, affecting the precise approach to personalized treatment. Accurate subtyping can lead to better survival rates for cancer patients. High-throughput technologies provide multiple omics data for cancer…

机器学习 · 计算机科学 2022-08-01 Hai Yang , Yuhang Sheng , Yi Jiang , Xiaoyang Fang , Dongdong Li , Jing Zhang , Zhe Wang

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

In anti-cancer drug development, a major scientific challenge is disentangling the complex relationships between high-dimensional genomics data from patient tumor samples, the corresponding tumor's organ of origin, the drug targets…

机器学习 · 计算机科学 2024-03-29 Omid Bazgir , Zichen Wang , Ji Won Park , Marc Hafner , James Lu

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

图像与视频处理 · 电气工程与系统科学 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

In this paper, we propose a Computer Assisted Diagnosis (CAD) system based on a deep Convolutional Neural Network (CNN) model, to build an end-to-end learning process that classifies breast mass lesions. We investigate the impact that has…

计算机视觉与模式识别 · 计算机科学 2017-11-30 Hiba Chougrad , Hamid Zouaki , Omar Alheyane

Neural networks have proved to be very robust at processing unstructured data like images, text, videos, and audio. However, it has been observed that their performance is not up to the mark in tabular data; hence tree-based models are…

机器学习 · 计算机科学 2022-04-25 Tushar Sarkar

In 2020, prostate cancer saw a staggering 1.4 million new cases, resulting in over 375,000 deaths. The accurate identification of clinically significant prostate cancer is crucial for delivering effective treatment to patients.…

图像与视频处理 · 电气工程与系统科学 2024-05-14 Chi-en Amy Tai , Alexander Wong

To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…

图像与视频处理 · 电气工程与系统科学 2024-09-12 Weimin Wang , Yufeng Li , Xu Yan , Mingxuan Xiao , Min Gao

Recent advances in graph convolutional networks have significantly improved the performance of chemical predictions, raising a new research question: "how do we explain the predictions of graph convolutional networks?" A possible approach…

Deep learning has introduced several learning-based methods to recognize breast tumours and presents high applicability in breast cancer diagnostics. It has presented itself as a practical installment in Computer-Aided Diagnostic (CAD)…

图像与视频处理 · 电气工程与系统科学 2022-02-15 Timothy Kwong , Samaneh Mazaheri

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

机器学习 · 计算机科学 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

With recent advancements in the development of artificial intelligence applications using theories and algorithms in machine learning, many accurate models can be created to train and predict on given datasets. With the realization of the…

机器学习 · 计算机科学 2024-03-29 Pei Xi , Lin

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Tabular data is prevalent across diverse domains in machine learning. With the rapid progress of deep tabular prediction methods, especially pretrained (foundation) models, there is a growing need to evaluate these methods systematically…

机器学习 · 计算机科学 2025-11-10 Han-Jia Ye , Si-Yang Liu , Hao-Run Cai , Qi-Le Zhou , De-Chuan Zhan

We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the data, however is it not discovered automatically given the noise and low numbers of samples used in…

基因组学 · 定量生物学 2018-06-20 Francis Dutil , Joseph Paul Cohen , Martin Weiss , Georgy Derevyanko , Yoshua Bengio