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Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within microvessels can be estimated. However, a 2D super-resolution…

Full-color imaging is significant in digital pathology. Compared with a grayscale image or a pseudo-color image that only contains the contrast information, it can identify and detect the target object better with color texture information.…

图像与视频处理 · 电气工程与系统科学 2022-04-26 Yuting Gao , Jiurun Chen , Aiye Wang , An Pan , Caiwen Ma , Baoli Yao

Medical image segmentation is a critical step in computer-aided diagnosis, and convolutional neural networks are popular segmentation networks nowadays. However, the inherent local operation characteristics make it difficult to focus on the…

计算机视觉与模式识别 · 计算机科学 2023-05-18 Fenghe Tang , Jianrui Ding , Lingtao Wang , Min Xian , Chunping Ning

The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…

In the case of vector flow imaging systems, the most employed flow estimation techniques are the directional beamforming based cross correlation and the triangulation-based autocorrelation. However, the directional beamforming-based…

信号处理 · 电气工程与系统科学 2022-06-07 A. N. Madhavanunni , Mahesh Raveendranatha Panicker

Imaging of biological cells and tissues often relies on fluorescent labels, which offer high contrast with molecular specificity. The use of exogenous labeling agents, however, may alter the normal physiology of the bio-specimens.…

仪器与探测器 · 物理学 2019-10-01 Zichao Bian , Shaowei Jiang , Pengming Song , He Zhang , Pouria Hoveida , Kazunori Hoshino , Guoan Zheng

Unsupervised video-based surgical instrument segmentation has the potential to accelerate the adoption of robot-assisted procedures by reducing the reliance on manual annotations. However, the generally low quality of optical flow in…

计算机视觉与模式识别 · 计算机科学 2025-03-27 Yang Liu , Peiran Wu , Jiayu Huo , Gongyu Zhang , Zhen Yuan , Christos Bergeles , Rachel Sparks , Prokar Dasgupta , Alejandro Granados , Sebastien Ourselin

Raman microscopy is a powerful method combining non-invasiveness with no special sample preparation. Because of this remarkable simplicity, it has been widely exploited in many fields, ranging from life and materials sciences, to…

Patient derived xenograft (PDX) tumor models initiated in avian chorioallantoic membranes (CAM) are under investigation to evaluate the effectiveness of therapeutic options with the objective of personalizing treatments. CAM PDXs paired…

Advances in silicon photonics have resulted in rapidly increasing complexity of integrated circuits. New methods are desirable that allow direct characterization of individual optical components in-situ, without the need for additional…

Visualizing the details of different cellular structures is of great importance to elucidate cellular functions. However, it is challenging to obtain high quality images of different structures directly due to complex cellular environments.…

图像与视频处理 · 电气工程与系统科学 2019-10-01 Yi Liu , Hao Yuan , Zhengyang Wang , Shuiwang Ji

The characterization of white blood cells (WBCs) is crucial for blood analyses and disease diagnoses. However, current standard techniques rely on cell labeling, a process which imposes significant limitations. Here we present…

生物物理 · 物理学 2015-05-12 Jonghee Yoon , Kyoohyun Kim , HyunJoo Park , Chulhee Choi , Seongsoo Jang , YongKeun Park

Super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) offers a high-resolution view of microvascular structures. Yet, ULM image quality heavily relies on precise microbubble (MB) detection. Despite the crucial…

人工智能 · 计算机科学 2026-01-15 Sepideh K. Gharamaleki , Brandon Helfield , Hassan Rivaz

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

定量方法 · 定量生物学 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Diagnostic imaging plays a critical role in healthcare, serving as a fundamental asset for timely diagnosis, disease staging and management as well as for treatment choice, planning, guidance, and follow-up. Among the diagnostic imaging…

信号处理 · 电气工程与系统科学 2021-09-24 Ruud JG van Sloun , Jong Chul Ye , Yonina C Eldar

Deep-ultraviolet (DUV) microscopy can provide label-free biochemical contrast by exploiting the intrinsic absorption of nucleic acids, proteins and lipids, offering chemically specific morphological information that complements structural…

Far-field chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological, material, and chemical systems. Chemical microscopy provides a…

光学 · 物理学 2023-06-06 Mingwei Tang , Yubing Han , Danchen Jia , Qing Yang , Ji-Xin Cheng

Ultra-fast transmission electron microscopy (UTEM) combines sub-picosecond time-resolution with the versatility of TEM spectroscopies. It allows one to study the dynamics of materials properties combining complementary techniques. However,…

材料科学 · 物理学 2021-08-25 S. Meuret , L. H. G. Tizei , F. Houdellier , S. Weber , Y. Auad , M. Tencé , H. -C. Chang , M. Kociak , A. Arbouet

The first choice in diagnostic imaging for patients suffering from peripheral arterial disease is 2D ultrasound (US). However, for a proper imaging process, a skilled and experienced sonographer is required. Additionally, it is a highly…

Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain…

物理教育 · 物理学 2019-07-24 Stephane Perrin , Keshia Badu , Paul Montgomery , Sylvain Lecler