相关论文: Optimal Control of Covid-19 Interventions in Publi…

After the COVID-19 pandemic, we saw an increase in demand for epidemiological mathematical models. The goal of this work is to study the optimal control for an age-structured model as a strategy of quarantine of infected people, which is…

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

The COVID-19 pandemic has completely disrupted the operation of our societies. Its elusive transmission process, characterized by an unusually long incubation period, as well as a high contagion capacity, has forced many countries to take…

Optimal control problems reflecting the finding of effective quarantine strategies are considered for two control SEIR~type models describing the spread of the COVID-19 virus in the human population. The properties of the corresponding…

Cost-effectiveness analysis is a mode of determining both the cost and economic health outcomes of one or more control interventions. In this work, we have formulated a non-autonomous nonlinear deterministic model to study the control of…

We investigate, through a fractional mathematical model, the effects of physical distance on the SARS-CoV-2 virus transmission. Two controls are considered in our model for eradication of the spread of COVID-19: media education, through…

Optimal control theory in epidemiology has been used to establish the most effective intervention strategies for managing and mitigating the spread of infectious diseases while considering constraints and costs. Using Pontryagin's Maximum…

Governments across the world are currently facing the task of selecting suitable intervention strategies to cope with the effects of the COVID-19 pandemic. This is a highly challenging task, since harsh measures may result in economic…

We apply optimal control theory to a generalized SEIR-type model. The proposed system has three controls, representing social distancing, preventive means, and treatment measures to combat the spread of the COVID-19 pandemic. We analyze…

This paper investigates the optimal control of an epidemic governed by a SEIR model with an operational delay in vaccination. We address the mathematical challenge of imposing hard healthcare capacity constraints (e.g., ICU limits) over an…

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Almost every country in the world is battling to limit the spread of COVID-19. As the world strives to get an effective medication to control the disease, appropriate intervention measures, for now, remains one of the effective methods to…

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

This research introduces a new approach utilizing optimal control theory (OCT) to assess the Social Optimum (SO) of a vaccination game, navigating the intricate considerations of cost, availability, and distribution policies. By integrating…

Several non-pharmaceutical interventions have been proposed to control the spread of the COVID-19 pandemic. On the large scale, these empirical solutions, often associated with extended and complete lockdowns, attempt to minimize the costs…

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…