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We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

神经元与认知 · 定量生物学 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

神经元与认知 · 定量生物学 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to…

神经元与认知 · 定量生物学 2014-07-17 Eric Jonas , Konrad Kording

The first step to understanding brain function is to determine the brain's network structure. We report a three-dimensional analysis of the brain network of the fruit fly Drosophila melanogaster by synchrotron-radiation tomographic…

神经元与认知 · 定量生物学 2016-09-09 Ryuta Mizutani , Rino Saiga , Akihisa Takeuchi , Kentaro Uesugi , Yoshio Suzuki

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

计算机视觉与模式识别 · 计算机科学 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

Our work is concerned with the generation and targeted design of RNA, a type of genetic macromolecule that can adopt complex structures which influence their cellular activities and functions. The design of large scale and complex…

生物大分子 · 定量生物学 2021-02-02 Zichao Yan , William L. Hamilton , Mathieu Blanchette

For much of biology, the manner in which genotype maps to phenotype remains a fundamental mystery. The few maps that are known tend to show modular pleiotropy: sets of phenotypes are determined by distinct sets of genes. One key map that…

We present a statistical framework that jointly models brain shape and functional connectivity, which are two complex aspects of the brain that have been classically studied independently. We adopt a Riemannian modeling approach to account…

统计方法学 · 统计学 2024-04-26 Eardi Lila , John A. D. Aston

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Machine learning techniques have become increasingly popular in the field of resting state fMRI (functional magnetic resonance imaging) network based classification. However, the application of convolutional networks has been proposed only…

机器学习 · 统计学 2017-07-24 Regina Meszlényi , Krisztian Buza , Zoltán Vidnyánszky

The study of dynamic functional connectomes has provided valuable insights into how patterns of brain activity change over time. Neural networks process information through artificial neurons, conceptually inspired by patterns of activation…

神经元与认知 · 定量生物学 2025-08-12 Yutong Wu , Peilin He , Tananun Songdechakraiwut

The main goal of this study is to extract a set of brain networks in multiple time-resolutions to analyze the connectivity patterns among the anatomic regions for a given cognitive task. We suggest a deep architecture which learns the…

The human braingraph, or connectome is a description of the connections of the brain: the nodes of the graph correspond to small areas of the gray matter, and two nodes are connected by an edge if a diffusion MRI-based workflow finds fibers…

神经元与认知 · 定量生物学 2015-07-02 Csaba Kerepesi , Balázs Szalkai , Bálint Varga , Vince Grolmusz

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

应用统计 · 统计学 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

Functional connectomes derived from functional magnetic resonance imaging have long been used to understand the functional organization of the brain. Nevertheless, a connectome is intrinsically linked to the atlas used to create it. In…

神经元与认知 · 定量生物学 2021-07-06 Javid Dadashkarimi , Amin Karbasi , Dustin Scheinost

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

神经元与认知 · 定量生物学 2024-08-06 Suman Kulkarni , Dani S. Bassett

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

神经元与认知 · 定量生物学 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

基因组学 · 定量生物学 2019-06-04 Tianle Ma , Aidong Zhang

Human intelligence relies in part on our brains' ability to create abstract mental models that succinctly capture the hidden blueprint of our reality. Such abstract world models notably allow us to rapidly navigate novel situations by…

人工智能 · 计算机科学 2023-12-12 Quentin RV. Ferry , Joshua Ching , Takashi Kawai

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

神经元与认知 · 定量生物学 2020-04-03 Christopher W. Lynn , Danielle S. Bassett