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Protein folding processes are a vital aspect of molecular biology that is hard to simulate with conventional computers. Quantum algorithms have been proven superior for certain problems and may help tackle this complex life science…

量子物理 · 物理学 2024-09-11 Hanna Linn , Isak Brundin , Laura García-Álvarez , Göran Johansson

Binding energy is a fundamental thermodynamic property that governs molecular interactions, playing a crucial role in fields such as healthcare and the natural sciences. It is particularly relevant in drug development, vaccine design, and…

量子物理 · 物理学 2025-08-06 Erico Souza Teixeira , Lucas Barros Fernandes , Yara Rodrigues Inácio

The rapid growth in the number of experimental and predicted protein structures and more complicated protein structures challenge users in computational biology for utilizing the structural information and protein surface property…

定量方法 · 定量生物学 2023-08-08 Junkang Wei , Jin Xiao , Siyuan Chen , Licheng Zong , Xin Gao , Yu Li

High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials. However, the interplay of structural and…

量子物理 · 物理学 2019-10-29 Alain Tchagang , Julio Valdés

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

量子物理 · 物理学 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

The field of computational chemistry is increasingly leveraging machine learning (ML) potentials to predict molecular properties with high accuracy and efficiency, providing a viable alternative to traditional quantum mechanical (QM)…

化学物理 · 物理学 2025-08-13 Arif Ullah , Yuxinxin Chen , Pavlo O. Dral

Presently, one of the most ambitious technological goals is the development of devices working under the laws of quantum mechanics. One prominent target is the quantum computer, which would allow the processing of information at quantum…

Quantum process tomography (QPT) is a fundamental tool for fully characterizing quantum systems. It relies on querying a set of quantum states as input to the quantum process. Previous QPT methods typically employ a straightforward strategy…

量子物理 · 物理学 2025-06-06 Jiaqi Yang , Xiaohua Xu , Wei Xie

As the method to completely characterize quantum dynamical processes, quantum process tomography (QPT) is vitally important for quantum information processing and quantum control, where the faithfulness of quantum devices plays an essential…

量子物理 · 物理学 2013-09-24 Yu-Xiang Zhang , Shengjun Wu , Zeng-Bing Chen

Quantum computing, an innovative computing system carrying prominent processing rate, is meant to be the solutions to problems in many fields. Among these realms, the most intuitive application is to help chemical researchers correctly…

量子物理 · 物理学 2022-12-29 Qingchun Wang , Huan-Yu Liu , Qing-Song Li , Jianyu Zhao , Qiankun Gong , Ye Li , Yu-Chun Wu , Guo-Ping Guo

We show that protein sequences can be thought of as sentences in natural language processing and can be parsed using the existing Quantum Natural Language framework into parameterized quantum circuits of reasonable qubits, which can be…

The ability of fully reconstructing quantum maps is a fundamental task of quantum information, in particular when coupling with the environment and experimental imperfections of devices are taken into account. In this context we carry out a…

量子物理 · 物理学 2010-11-04 I. Bongioanni , L. Sansoni , F. Sciarrino , G. Vallone , P. Mataloni

The development of accurate and efficient machine learning models for predicting the structure and properties of molecular crystals has been hindered by the scarcity of publicly available datasets of structures with property labels. To…

Comparing probability distributions is a core challenge across the natural, social, and computational sciences. Existing methods, such as Maximum Mean Discrepancy (MMD), struggle in high-dimensional and non-compact domains. Here we…

机器学习 · 统计学 2025-09-09 Logan S. McCarty

Quantum state tomography (QST) is a fundamental task in quantum information science that aims to reconstruct unknown quantum states from measurement data. However, the exponential growth of Hilbert-space dimension with system size makes…

量子物理 · 物理学 2026-05-27 Zhen Qin , Michael B. Wakin , Zhihui Zhu

The training of molecular models of quantum mechanical properties based on statistical machine learning requires large datasets which exemplify the map from chemical structure to molecular property. Intelligent a priori selection of…

Free energy calculations are at the heart of physics-based analyses of biochemical processes. They allow us to quantify molecular recognition mechanisms, which determine a wide range of biological phenomena from how cells send and receive…

Quantum neuromorphic computing (QNC) is a sub-field of quantum machine learning (QML) that capitalizes on inherent system dynamics. As a result, QNC can run on contemporary, noisy quantum hardware and is poised to realize challenging…

量子物理 · 物理学 2024-02-22 Rodrigo Araiza Bravo , Khadijeh Najafi , Taylor L. Patti , Xun Gao , Susanne F. Yelin

Due to rapid advancements in deep learning techniques, the demand for large-volume high-quality databases grows significantly in chemical research. We developed a quantum-chemistry database that includes 443,106 small organic molecules with…

化学物理 · 物理学 2024-06-05 Yifei Zhu , Mengge Li , Chao Xu , Zhenggang Lan

A fundamental task in photonics is to characterise an unknown optical process, defined by properties such as birefringence, spectral response, thickness and flatness. Amongst many ways to achieve this, single-photon probes can be used in a…