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We propose a physical model for developmental process at cellular level to discuss the mechanism of epigenetic landscape. In our simplified model, a minimal model, the network of the interaction among cells generates the landscape…

细胞行为 · 定量生物学 2014-02-04 Motoki Nakagawa , Osamu Narikiyo

Understanding systems level behaviour of many interacting agents is challenging in various ways, here we'll focus on the how the interaction between components can lead to hierarchical structures with different types of dynamics, or…

种群与进化 · 定量生物学 2018-12-26 Henrik Jeldtoft Jensen

Functional responses are widely used to describe interactions and resources exchange between individuals in ecology. The form given to functional responses dramatically affects the dynamics and stability of populations and communities.…

种群与进化 · 定量生物学 2018-08-16 S. Billiard , V. Bansaye , J. -R. Chazottes

Active systems across scales, ranging from molecular machines to human crowds, are usually modeled as assemblies of self-propelled particles driven by internally generated forces. However, these models often assume memoryless dynamics and…

统计力学 · 物理学 2025-12-10 Marc Besse , Raphaël Voituriez

In any ecosystem, the conditions of the environment and the characteristics of the species that inhabit it are entangled, co-evolving in space and time. We introduce a model that couples active agents with a dynamic environment, interpreted…

种群与进化 · 定量生物学 2025-12-10 G. Briozzo , G. J. Sibona , F. Peruani

We explore how physical scale and population size shape the emergence of complex behaviors in open-ended ecological environments. In our setting, agents are unsupervised and have no explicit rewards or learning objectives but instead evolve…

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

细胞行为 · 定量生物学 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

The physical interpretation of the functioning of the adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an adaptive self-organizing biological system in…

分子网络 · 定量生物学 2023-05-19 Jozsef Prechl

In order to better understand the occurrence of phase transitions, we adopt an approach based on the study of energy landscapes: The relation between stationary points of the potential energy landscape of a classical many-particle system…

统计力学 · 物理学 2009-03-24 Michael Kastner

Phase separation has emerged as an essential concept for the spatial organization inside biological cells. However, despite the clear relevance to virtually all physiological functions, we understand surprisingly little about what phases…

生物物理 · 物理学 2022-08-10 David Zwicker , Liedewij Laan

We introduce a model of adaptive temporal networks whose evolution is regulated by an interplay between node activity and dynamic exchange of information through links. We study the model by using a master equation approach. Starting from a…

物理与社会 · 物理学 2016-04-18 Takaaki Aoki , Luis E. C. Rocha , Thilo Gross

These lecture notes are designed to provide a brief introduction into the phenomenology of active matter and to present some of the analytical tools used to rationalize the emergent behavior of active systems. Such systems are made of…

软凝聚态物质 · 物理学 2018-07-02 Étienne Fodor , M. Cristina Marchetti

We apply the formalism of dynamical system analysis to investigate the evolution of interacting dark energy scenarios at the background and perturbation levels in a unified way. Since the resulting dynamical system contains the extra…

广义相对论与量子宇宙学 · 物理学 2022-02-10 Wompherdeiki Khyllep , Jibitesh Dutta , Spyros Basilakos , Emmanuel N. Saridakis

The description of activated relaxation of glassy systems in the multidimensional configurational space is a long-standing open problem. We develop a phenomenological description of the out-of-equilibrium dynamics of a model with a rough…

无序系统与神经网络 · 物理学 2014-10-09 Chiara Cammarota , Enzo Marinari

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Competition for a limited resource is the hallmark of many complex systems, and often, that resource turns out to be the physical space itself. In this work, we study a novel model designed to elucidate the dynamics and emergence in complex…

物理与社会 · 物理学 2026-03-18 Ann Mary Mathew , V Sasidevan

Energy landscapes are high-dimensional surfaces representing the dependence of system energy on variable configurations, which determine crucially the system's emergent behavior but are difficult to be analyzed due to their high-dimensional…

无序系统与神经网络 · 物理学 2024-05-24 Ho Fai Po , Chi Ho Yeung

Evolutionary adaptation is the process that increases the fit of a population to the fitness landscape it inhabits. As a consequence, evolutionary dynamics is shaped, constrained, and channeled, by that fitness landscape. Much work has been…

种群与进化 · 定量生物学 2010-12-17 Bjørn Østman , Arend Hintze , Christoph Adami

Learning, inference, and emergence in biological and artificial systems are often studied within disparate theoretical frameworks, ranging from energy-based models to recurrent and attention-based architectures. Here we develop a unified…

神经元与认知 · 定量生物学 2026-01-22 Byung Gyu Chae

Recent developments have created the ability to quantify information flow among components that interact in a dynamical system, and have led to significant advances in characterizing the dependence between the variables involved. In…

数据分析、统计与概率 · 物理学 2023-09-27 Praveen Kumar
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