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This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…

机器学习 · 计算机科学 2026-01-27 Ramiro Valdes Jara , Adam Meyers

In this study we present a novel computational model for unprecedented simulations of the whole cardiac electrophysiology. According to the heterogeneous electrophysiologic properties of the heart, the whole cardiac geometry is decomposed…

医学物理 · 物理学 2022-03-14 Giulio Del Corso , Roberto Verzicco , Francesco Viola

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. For this reason, many approaches have been developed to best estimate the cardiac muscle deformation, and to obtain a practical model to use in…

计算工程、金融与科学 · 计算机科学 2014-12-09 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedicated…

We report three-dimensional and time-dependent numerical simulations of the propagation of electrical action potentials in a model of rabbit ventricular tissue. The simulations are performed using a finite-element method for the solution of…

定量方法 · 定量生物学 2021-05-20 Peter Mortensen , Muhamad H. N. Aziz , Hao Gao , Radostin D. Simitev

Modeling the behavior of biological tissues and organs often necessitates the knowledge of their shape in the absence of external loads. However, when their geometry is acquired in-vivo through imaging techniques, bodies are typically…

生物物理 · 物理学 2024-02-27 N. A. Barnafi , F. Regazzoni , D. Riccobelli

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…

最优化与控制 · 数学 2021-02-03 Thomas Grandits , Simone Pezzuto , Jolijn M. Lubrecht , Thomas Pock , Gernot Plank , Rolf Krause

The structure and function of biological molecules are strongly influenced by the water and dissolved ions that surround them. This aqueous solution (solvent) exerts significant electrostatic forces in response to the biomolecule's…

数值分析 · 数学 2015-12-29 Matthew G. Knepley , Jaydeep P. Bardhan

In this paper, we present a discussion on the algorithms design of Electrical Impedance Tomography (EIT) for biomedical applications. Based on the Maxwell differential equations and the derived the finite element(FE) linear equations, we…

信号处理 · 电气工程与系统科学 2019-01-23 Mingyong Zhou , Hongyu Zhu

We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To…

偏微分方程分析 · 数学 2018-11-20 Erik Grandelius , Kenneth H. Karlsen

High-resolution and anatomically realistic computer models of biological soft tissues play a significant role in the understanding of the function of cardiovascular components in health and disease. However, the computational effort to…

医学物理 · 物理学 2015-08-12 Christoph M. Augustin , Gerhard A. Holzapfel , Olaf Steinbach

Electron microscopy (EM) imaging offers unparalleled resolution for analyzing neural tissues, crucial for uncovering the intricacies of synaptic connections and neural processes fundamental to understanding behavioral mechanisms. Recently,…

计算机视觉与模式识别 · 计算机科学 2024-08-27 Ruohua Shi , Qiufan Pang , Lei Ma , Lingyu Duan , Tiejun Huang , Tingting Jiang

We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

Based on recent experiments with time-lapse fluorescent imaging, we propose a cellular automaton model for the dynamics of vascular endothelial cells (ECs) in angiogenic morphogenesis. The model successfully reproduces cell mixing behavior,…

元胞自动机与格子气 · 物理学 2015-07-22 Keisuke Matsuya , Hiroki Kurihara , Tetsuji Tokihiro

This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria. One of…

医学物理 · 物理学 2015-09-04 Elisa Schenone , Annabelle Collin , Jean-Frédéric Gerbeau

Purpose: Point-of-care MRI requires operation outside of a faraday shielded room normally used to block image-degrading electromagnetic Interference (EMI). To address this, we introduce the EDITER method, an external sensor based dynamic…

In the framework of accurate and efficient segregated schemes for 3D cardiac electromechanics and 0D cardiovascular models, we propose here a novel numerical approach to address the coupled 3D-0D problem introduced in Part I of this…

Electrocardiogram (ECG) analysis is a fundamental tool for diagnosing cardiovascular conditions, yet anomaly detection in ECG signals remains challenging due to their inherent complexity and variability. We propose Multi-scale Masked…

机器学习 · 计算机科学 2025-02-11 Ya Zhou , Yujie Yang , Jianhuang Gan , Xiangjie Li , Jing Yuan , Wei Zhao

This paper introduces an accurate edge-based smoothed finite element method (ES-FEM) for electromagnetic analysis for both two dimensional cylindrical and three dimensional cartesian systems, which shows much better performance in terms of…

计算工程、金融与科学 · 计算机科学 2019-10-30 Yangfan Zhang , Pengfei Wang , Wenping Li , Shunchuan Yang

The presented paper concentrates on the boundary element method (BEM) for the heat equation in three spatial dimensions. In particular, we deal with tensor product space-time meshes allowing for quadrature schemes analytic in time and…

数值分析 · 数学 2021-11-23 Jan Zapletal , Raphael Watschinger , Günther Of , Michal Merta