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Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

计算机视觉与模式识别 · 计算机科学 2022-07-27 Kevin Thandiackal , Boqi Chen , Pushpak Pati , Guillaume Jaume , Drew F. K. Williamson , Maria Gabrani , Orcun Goksel

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

计算机视觉与模式识别 · 计算机科学 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

The integration of Computer-Aided Diagnosis (CAD) with Large Language Models (LLMs) presents a promising frontier in clinical applications, notably in automating diagnostic processes akin to those performed by radiologists and providing…

计算机视觉与模式识别 · 计算机科学 2024-05-22 Zihao Zhao , Sheng Wang , Jinchen Gu , Yitao Zhu , Lanzhuju Mei , Zixu Zhuang , Zhiming Cui , Qian Wang , Dinggang Shen

Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Wenhao Tang , Heng Fang , Ge Wu , Xiang Li , Ming-Ming Cheng

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Ruicheng Yuan , Zhenxuan Zhang , Anbang Wang , Liwei Hu , Xiangqian Hua , Yaya Peng , Jiawei Luo , Guang Yang

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Multimodal Large Language Model (MLLM) has recently garnered attention as a prominent research focus. By harnessing powerful LLM, it facilitates a transition of conversational generative AI from unimodal text to performing multimodal tasks.…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Xuechen Guo , Wenhao Chai , Shi-Yan Li , Gaoang Wang

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Accurate prediction of placental diseases via whole slide images (WSIs) is critical for preventing severe maternal and fetal complications. However, WSI analysis presents significant computational challenges due to the massive data volume.…

计算机视觉与模式识别 · 计算机科学 2025-08-06 Hang Guo , Qing Zhang , Zixuan Gao , Siyuan Yang , Shulin Peng , Xiang Tao , Ting Yu , Yan Wang , Qingli Li

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

计算与语言 · 计算机科学 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

图像与视频处理 · 电气工程与系统科学 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial…

Colonoscopic polyp diagnosis is pivotal for early colorectal cancer detection, yet traditional automated reporting suffers from inconsistencies and hallucinations due to the scarcity of high-quality multimodal medical data. To bridge this…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Tianyu Zhou , Junyi Tang , Zehui Li , Dahong Qian , Suncheng Xiang

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

人工智能 · 计算机科学 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

计算与语言 · 计算机科学 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Recently, large language models (LLMs) have taken the spotlight in natural language processing. Further, integrating LLMs with vision enables the users to explore emergent abilities with multimodal data. Visual language models (VLMs), such…

计算机视觉与模式识别 · 计算机科学 2024-02-23 Minh-Hao Van , Prateek Verma , Xintao Wu
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