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Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

计算与语言 · 计算机科学 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez

Machine learning techniques combined with in-home monitoring technologies provide a unique opportunity to automate diagnosis and early detection of adverse health conditions in long-term conditions such as dementia. However, accessing…

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

医学物理 · 物理学 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Early detection of dementia is very crucial to ensure treatment begins on time, however it is difficult to choose appropriate cognitive assessment tools because each test is designed differently and may not be tailored to the needs of a…

定量方法 · 定量生物学 2025-05-13 Saransh Naole , Dhriti Parikh , Sakshi Nayak , Swarna Priya Ramu

The prediction of mild cognitive impairment (MCI) conversion to Alzheimer's disease (AD) is important for early treatment to prevent or slow the progression of AD. To accurately predict the MCI conversion to stable MCI or progressive MCI,…

计算机视觉与模式识别 · 计算机科学 2023-07-17 Linfeng Liu , Junyan Lyu , Siyu Liu , Xiaoying Tang , Shekhar S. Chandra , Fatima A. Nasrallah

This study investigates clinicians' perceptions and attitudes toward an assistive artificial intelligence (AI) system that employs a speech-based explainable ML algorithm for detecting depression. The AI system detects depression from…

人机交互 · 计算机科学 2024-10-25 Kexin Feng , Theodora Chaspari

People living with dementia (PLwD) often show gradual shifts in how they communicate, becoming less expressive, more repetitive, or drifting off-topic in subtle ways. While caregivers may notice these changes informally, most computational…

人工智能 · 计算机科学 2025-11-21 Joy Lai , Alex Mihailidis

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

人工智能 · 计算机科学 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Current progress in the artificial intelligence domain has led to the development of various types of AI-powered dementia assessments, which can be employed to identify patients at the early stage of dementia. It can revolutionize the…

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

神经元与认知 · 定量生物学 2022-08-19 Heng Kong , Shuqiang Wang

Aging and chronic conditions affect older adults' daily lives, making the early detection of developing health issues crucial. Weakness, which is common across many conditions, can subtly alter physical movements and daily activities.…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Chen Long-fei , Muhammad Ahmed Raza , Craig Innes , Subramanian Ramamoorthy , Robert B. Fisher

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

机器学习 · 计算机科学 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

This paper examines the relationship between informal caregiving and both cognitive functioning and healthcare utilization among older adults with dementia. Using data from the RAND version of the Health and Retirement Study (HRS), a…

综合经济学 · 经济学 2025-09-24 Mohammad Abdullah Al Faisal

Demographic shifts have led to an increase in mild cognitive impairment (MCI), and this study investigates the effects of cognitive training (CT) and reminiscence therapy (RT) conducted by humans or socially assistive robots (SARs) on…

We classify very-mild to moderate dementia in patients (CDR ranging from 0 to 2) using a support vector machine classifier acting on dimensionally reduced feature set derived from MRI brain scans of the 416 subjects available in the…

计算机视觉与模式识别 · 计算机科学 2014-06-26 V. A. Miller , S. Erlien , J. Piersol

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

神经元与认知 · 定量生物学 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Cecilia Ostertag , Marie Beurton-Aimar , Thierry Urruty

Edge-based multimodal medical monitoring requires models that balance diagnostic accuracy with severe energy constraints. Continuous acquisition of ECG, PPG, EMG, and IMU streams rapidly drains wearable batteries, often limiting operation…

INTRODUCTION: Detecting functional decline from normal ageing to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL-Q) was developed: a 70-item proxy-based tool with good…