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Histopathology images are crucial to the study of complex diseases such as cancer. The histologic characteristics of nuclei play a key role in disease diagnosis, prognosis and analysis. In this work, we propose a sparse Convolutional…

计算机视觉与模式识别 · 计算机科学 2017-04-11 Le Hou , Vu Nguyen , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , Tianhao Zhao , Joel H. Saltz

In classification problems, supervised machine-learning methods outperform traditional algorithms, thanks to the ability of neural networks to learn complex patterns. However, in two-class classification tasks like anomaly or fraud…

机器学习 · 计算机科学 2022-04-01 Mihai-Cezar Augustin , Vivien Bonvin , Regis Houssou , Efstratios Rappos , Stephan Robert-Nicoud

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based autoencoders have shown great potential in detecting anomalies in medical images. However, especially…

图像与视频处理 · 电气工程与系统科学 2020-01-03 David Zimmerer , Simon Kohl , Jens Petersen , Fabian Isensee , Klaus Maier-Hein

The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…

图像与视频处理 · 电气工程与系统科学 2021-06-22 Zeyu Gao , Jiangbo Shi , Xianli Zhang , Yang Li , Haichuan Zhang , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

In this paper, we introduced a novel feature extraction approach, named exclusive autoencoder (XAE), which is a supervised version of autoencoder (AE), able to largely improve the performance of nucleus detection and classification on…

计算机视觉与模式识别 · 计算机科学 2018-11-29 Chao-Hui Huang , Daniel Racoceanu

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based auto encoders have shown great potential in detecting anomalies in medical images. However, state-of-the-art…

机器学习 · 计算机科学 2018-12-17 David Zimmerer , Simon A. A. Kohl , Jens Petersen , Fabian Isensee , Klaus H. Maier-Hein

In this paper, we propose Normality-Calibrated Autoencoder (NCAE), which can boost anomaly detection performance on the contaminated datasets without any prior information or explicit abnormal samples in the training phase. The NCAE…

机器学习 · 计算机科学 2021-10-29 Jongmin Yu , Hyeontaek Oh , Minkyung Kim , Junsik Kim

A feature learning task involves training models that are capable of inferring good representations (transformations of the original space) from input data alone. When working with limited or unlabelled data, and also when multiple visual…

计算机视觉与模式识别 · 计算机科学 2018-11-02 Gabriel B. Cavallari , Leonardo Sampaio Ferraz Ribeiro , Moacir Antonelli Ponti

We show that compact fully connected (FC) deep learning networks trained to classify wireless protocols using a hierarchy of multiple denoising autoencoders (AEs) outperform reference FC networks trained in a typical way, i.e., with a…

网络与互联网体系结构 · 计算机科学 2019-04-29 Silvija Kokalj-Filipovic , Rob Miller , Joshua Morman

Pan-cancer classification using transcriptomic (RNA-Seq) data can inform tumor subtyping and therapy selection, but is challenging due to extremely high dimensionality and limited sample sizes. In this study, we propose a novel deep…

基因组学 · 定量生物学 2025-08-06 Vinil Polepalli

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

基因组学 · 定量生物学 2017-11-15 Gregory P. Way , Casey S. Greene

This paper proposes an autoencoder (AE) that is used for improving the performance of once-class classifiers for the purpose of detecting anomalies. Traditional one-class classifiers (OCCs) perform poorly under certain conditions such as…

机器学习 · 计算机科学 2020-01-01 Kasra Babaei , ZhiYuan Chen , Tomas Maul

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…

Cancer is still one of the most devastating diseases of our time. One way of automatically classifying tumor samples is by analyzing its derived molecular information (i.e., its genes expression signatures). In this work, we aim to…

机器学习 · 计算机科学 2020-01-16 Mafalda Falcao Ferreira , Rui Camacho , Luis F. Teixeira

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

计算机视觉与模式识别 · 计算机科学 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

Anomaly detection in images plays a significant role for many applications across all industries, such as disease diagnosis in healthcare or quality assurance in manufacturing. Manual inspection of images, when extended over a monotonously…

计算机视觉与模式识别 · 计算机科学 2021-07-21 Vincent Wilmet , Sauraj Verma , Tabea Redl , Håkon Sandaker , Zhenning Li

Classic variational autoencoders are used to learn complex data distributions, that are built on standard function approximators. Especially, VAE has shown promise on a lot of complex task. In this paper, a new autoencoder model -…

计算机视觉与模式识别 · 计算机科学 2020-01-13 Qiuyu Zhu , Ruixin Zhang

Classical machine learning often struggles with complex, high-dimensional data. Quantum machine learning offers a potential solution, promising more efficient processing. The quantum convolutional neural network (QCNN), a hybrid algorithm,…

量子物理 · 物理学 2025-07-25 Hinako Asaoka , Kazue Kudo

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

图像与视频处理 · 电气工程与系统科学 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li
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