相关论文: Probabilistic plugging of airways by sliding mucus…

Lung airways are lined by a film of mucus which protects the epithelium from inhaled particles. To maintain a uniform coating, the mucus that is secreted into airways must be distributed into a film by wall-attached cilia, which constantly…

Airway clearance by coughing is a key mechanism for mucus transport, particularly in obstructive lung diseases associated with altered mucus rheology. We investigate the dynamics of a viscoplastic liquid film driven by flow in a turbulent…

In this paper, we investigate both experimentally and theoretically the dynamics of a liquid plug driven by a cyclic periodic forcing inside a cylindrical rigid capillary tube. First, it is shown that depending on the type of forcing (flow…

One mechanism for airway closure in the lung is the surface-tension-driven instability of the mucus layer which lines the airway wall. We study the instability of an axisymmetric layer of viscoplastic Bingham liquid coating the interior of…

A liquid film wetting the interior of a long circular cylinder redistributes under the action of surface tension to form annular collars or occlusive plugs. These equilibrium structures are invariant under axial translation within a…

To assess how the presence of surfactant in lung airways alters the flow of mucus that leads to plug formation and airway closure, we investigate the effect of insoluble surfactant on the instability of a viscoplastic liquid coating the…

Flow of a thin viscous film down a flat inclined plane becomes unstable to long wave interfacial fluctuations when the Reynolds number based on the mean film thickness becomes larger than a critical value (this value decreases as the angle…

Flows through porous media can carry suspended and dissolved materials. These sediments may deposit inside the pore-space and alter its geometry. In turn, the changing pore structure modifies the preferential flow paths, resulting in a…

We study the transport of inertial particles in water flow in porous media. Our interest lies in understanding the accumulation of particles including the possibility of clogging. We propose that accumulation can be a result of hydrodynamic…

We consider a cylindrical film of fluid adhering to a rigid cylinder of fixed radius. The main result is to give the critical (maximum) length for which such a film of given thickness can be stable. The problem is considered both when the…

The sudden arrest of motion due to confinement is commonly observed via the clogging transition in the flow of particles through a constriction. We present results of a simple experiment to elucidate a similar transition in the…

It is shown how the combination of atomic deposition and nonlinear diffusion may lead, below a critical temperature, to the growth of nonuniform layers on a substrate. The dynamics of such a system is of the Cahn-Hilliard type, supplemented…

We study the transport and deposition of inhaled aerosols in a mid-generation, mucus-lined lung airway, with the aim of understanding if and how airborne particles can avoid the mucus and deposit on the airway wall -- an outcome that is…

An equilibrium phase diagram for the shape of compressively strained free-hanging films is developed by total strain energy minimization. For small strain gradients {\Delta}{\epsilon}, the film wrinkles, while for sufficiently large…

The dynamics of individual liquid plugs pushed at constant pressure head inside prewetted cylindrical capillary tubes is investigated experimentally and theoretically. It is shown that, depending on the thickness of the prewetting film and…

We theoretically study the Plateau-Rayleigh instability of a thin viscous film covering a fiber consisting of a rigid cylindrical core coated with a thin compressible elastic layer. We develop a soft-lubrication model, combining the…

Thin elastic sheets and membranes are known to wrinkle when they are stretched -- the associated physics is highly non-linear. The mechanics of thin films that exhibit unusual behavior upon stretching, when they possess auxetic structure,…

Many objects in nature and industry are wrapped in a thin sheet to enhance their chemical, mechanical, or optical properties. There are similarly a variety of methods for wrapping, from pressing a film onto a hard substrate, to using…

Thin liquid or gas films are everywhere in nature, from foams to submillimetric bubbles at a free surface, and their rupture leaves a collection of small drops and bubbles. However, the mechanisms at play responsible for the bursting of…

We consider a carpet of self-propelled particles at the liquid-gas interface of a liquid film on a solid substrate. The particles excert an excess pressure on the interface and also move along the interface while the swimming direction…