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Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection…

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

机器学习 · 计算机科学 2019-03-07 Avijit Mitra , Khalid Ashraf

Sepsis, a critical condition from the body's response to infection, poses a major global health crisis affecting all age groups. Timely detection and intervention are crucial for reducing healthcare expenses and improving patient outcomes.…

机器学习 · 计算机科学 2024-07-12 MohammadAmin Ansari Khoushabar , Parviz Ghafariasl

Mass casualty incidents (MCIs) overwhelm healthcare systems and demand rapid, accurate patient-hospital allocation decisions under extreme pressure. Here, we developed and validated a deep reinforcement learning-based decision-support AI…

机器学习 · 计算机科学 2025-09-11 Zhaoxun "Lorenz" Liu , Wagner H. Souza , Jay Han , Amin Madani

At-home physiotherapy compliance remains critically low due to a lack of personalized supervision and dynamic feedback. Existing digital health solutions rely on static, pre-recorded video libraries or generic 3D avatars that fail to…

人工智能 · 计算机科学 2026-04-24 Abhishek Dharmaratnakar , Srivaths Ranganathan , Anushree Sinha , Debanshu Das

Motivation: Many researchers with domain expertise are unable to easily apply machine learning to their bioinformatics data due to a lack of machine learning and/or coding expertise. Methods that have been proposed thus far to automate…

机器学习 · 计算机科学 2020-04-29 William La Cava , Heather Williams , Weixuan Fu , Steve Vitale , Durga Srivatsan , Jason H. Moore

Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but clinician acceptance remains a critical barrier. We developed a novel decision support interface that provides interpretable treatment…

人机交互 · 计算机科学 2023-02-02 Venkatesh Sivaraman , Leigh A. Bukowski , Joel Levin , Jeremy M. Kahn , Adam Perer

Caregivers of individuals with autism spectrum disorder (ASD) often find the 77-item Autism Treatment Evaluation Checklist (ATEC) burdensome, limiting its use for routine monitoring. This study introduces a generalizable machine learning…

应用统计 · 统计学 2025-11-03 Audrey Dong , Claire Xu , Samuel R. Guo , Kevin Yang , Xue-Jun Kong

Background: While machine learning (ML) models are rapidly emerging as promising screening tools in critical care medicine, the identification of homogeneous subphenotypes within populations with heterogeneous conditions such as pediatric…

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

机器学习 · 计算机科学 2025-11-11 Atharva Thakur , Shruti Dhumal

Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research…

人工智能 · 计算机科学 2025-03-18 Zhen Chen , Zhihao Peng , Xusheng Liang , Cheng Wang , Peigan Liang , Linsheng Zeng , Minjie Ju , Yixuan Yuan

With the growing prevalence of machine learning and artificial intelligence-based medical decision support systems, it is equally important to ensure that these systems provide patient outcomes in a fair and equitable fashion. This paper…

机器学习 · 统计学 2024-10-30 Jeffrey Smith , Andre Holder , Rishikesan Kamaleswaran , Yao Xie

The post-pandemic surge in healthcare demand, coupled with critical nursing shortages, has placed unprecedented pressure on medical triage systems, necessitating innovative AI-driven solutions. We present a multi-agent interactive…

人工智能 · 计算机科学 2025-08-05 Hongyan Cheng , Chengzhang Yu , Yanshu Shi , Chiyue Wang , Cong Liu , Zhanpeng Jin

Alzheimer's disease (AD) presents a complex, multifaceted challenge to patients, caregivers, and the healthcare system, necessitating integrated and dynamic support solutions. While artificial intelligence (AI) offers promising avenues for…

多智能体系统 · 计算机科学 2025-10-13 Adib Bazgir , Amir Habibdoust , Xing Song , Yuwen Zhang

Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…

定量方法 · 定量生物学 2020-11-24 Zina Ibrahim , Honghan Wu , Ahmed Hamoud , Lukas Stappen , Richard Dobson , Andrea Agarossi

Background Sepsis is one of the most life-threatening circumstances for critically ill patients in the US, while a standardized criteria for sepsis identification is still under development. Disparities in social determinants of sepsis…

机器学习 · 计算机科学 2021-12-16 Hanyin Wang , Yikuan Li , Andrew Naidech , Yuan Luo

Sepsis is an organ dysfunction caused by a deregulated immune response to an infection. Early sepsis prediction and identification allow for timely intervention, leading to improved clinical outcomes. Clinical calculators (e.g., the…

机器学习 · 计算机科学 2025-01-13 Changchang Yin , Shihan Fu , Bingsheng Yao , Thai-Hoang Pham , Weidan Cao , Dakuo Wang , Jeffrey Caterino , Ping Zhang

Background: Globally we face a projected shortage of 11 million healthcare practitioners by 2030, and administrative burden consumes 50% of clinical time. Artificial intelligence (AI) has the potential to help alleviate these problems.…

Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…

机器学习 · 计算机科学 2023-04-14 Kevin Ewig , Xiangwen Lin , Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

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