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How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

无序系统与神经网络 · 物理学 2020-03-11 Takashi Hayakawa , Tomoki Fukai

In cognitive network neuroscience, the connectivity and community structure of the brain network is related to cognition. Much of this research has focused on two measures of connectivity - modularity and flexibility - which frequently have…

神经元与认知 · 定量生物学 2017-11-28 Aurora I. Ramos-Nuñez , Simon Fischer-Baum , Randi Martin , Qiuhai Yue , Fengdan Ye , Michael W. Deem

The brain is an intricately structured organ responsible for the rich emergent dynamics that support the complex cognitive functions we enjoy as humans. With around $10^{11}$ neurons and $10^{15}$ synapses, understanding how the human brain…

神经元与认知 · 定量生物学 2019-02-12 Jason Z. Kim , Danielle S. Bassett

Control of nonlinear large-scale dynamical networks, e.g., collective behavior of agents interacting via a scale-free connection topology, is a central problem in many scientific and engineering fields. For the linear version of this…

最优化与控制 · 数学 2016-06-07 Kenji Kashima

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

神经元与认知 · 定量生物学 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Multivariate dynamical processes can often be intuitively described by a weighted connectivity graph between components representing each individual time-series. Even a simple representation of this graph as a Pearson correlation matrix may…

机器学习 · 计算机科学 2022-02-15 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

机器学习 · 计算机科学 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

Neurological and Physiological Disorders that impact emotional regulation each have their own unique characteristics which are important to understand in order to create a generalized solution to all of them. The purpose of this experiment…

人机交互 · 计算机科学 2024-11-25 Vedant Mehta

The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…

神经元与认知 · 定量生物学 2017-04-03 Ann E. Sizemore , Danielle S. Bassett

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

神经元与认知 · 定量生物学 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

神经元与认知 · 定量生物学 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Understanding the neural mechanisms underlying the transitions between different states of consciousness is a fundamental challenge in neuroscience. Thus, we investigate the underlying drivers of changes during the resting-state dynamics of…

神经元与认知 · 定量生物学 2024-07-10 Joseph Bodenheimer , Paul Bogdan , Sérgio Pequito , Arian Ashourvan

Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

应用统计 · 统计学 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

神经元与认知 · 定量生物学 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens

Neuroscientists have enjoyed much success in understanding brain functions by constructing brain connectivity networks using data collected under highly controlled experimental settings. However, these experimental settings bear little…

机器学习 · 统计学 2019-06-24 Kean Ming Tan , Junwei Lu , Tong Zhang , Han Liu

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

应用统计 · 统计学 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Short-term memory is essential for cognitive processing, yet our understanding of its neural mechanisms remains unclear. Neuroscience has long focused on how sequential activity patterns, where neurons fire one after another within large…

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

机器学习 · 统计学 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

统计力学 · 物理学 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz