相关论文: Linking Fluorescence Spectroscopy and 31P MRS in N…
Complete resection of malignant gliomas is hampered by the difficulty in distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists in reaching this goal. Using hyperspectral imaging, previous work…
A mathematical model of genome degradation is proposed that takes into account a variable rate of mutation and increasing number of cells in a developing human organism. The model explains known properties of cancer development, in…
Multitime correlation functions provide useful probes for the ensembles of trajectories underlying the stochastic dynamics of complex systems. These can be obtained by measuring their optical response to sequences of ultrashort optical…
Glioblastoma, a highly aggressive brain tumor with diverse molecular and pathological features, poses a diagnostic challenge due to its heterogeneity. Accurate diagnosis and assessment of this heterogeneity are essential for choosing the…
We study phase-dependent fluctuations of the resonance fluorescence of a single $\Lambda$-type three-level atom in the regime near coherent population trapping, i.e., alongside the two-photon detuning condition. To this end, we employ the…
MRI offers outstanding soft tissue contrast that may reduce uncertainties in target and organ-at-risk delineation and enable online adaptive image-guided treatment. Spatial distortions resulting from non-linearities in the gradient fields…
Purpose: Phosphorus Magnetic Resonance Spectroscopy (31P MRS) enables non-invasive assessment of energy metabolism, yet its application is hindered by sensitivity limitations. To overcome this, often high magnetic fields are used, leading…
Brain metabolites, such as N-acetylaspartate or myo-inositol, are constantly probing their local cellular environment under the effect of diffusion. Diffusion-weighted NMR spectroscopy therefore presents unparalleled potential to yield…
The radioactive glucose analogue 2-deoxy-2-[18F]fluoro-D-glucose (FDG) is widely used to reconstruct glucose metabolism and other biological functions in cells and tissues. The analysis of data on the time course of FDG tracer distribution…
Low- and intermediate mass stars experience a significant mass loss during the last phases of their evolution, which obscures them in a vast, dusty envelope. Although it has long been thought this envelope is generally spherically symmetric…
Nuclear magnetic resonance (NMR) spectroscopy is a widely used tool for chemical analysis and molecular structure identification. Because it typically relies on the weak magnetic fields produced by a small thermal nuclear spin polarization,…
The near-field and far-field spectral response of plasmonic systems are often assumed to be identical, due to the lack of methods that can directly compare and correlate both responses under similar environmental conditions. We develop a…
Functional alterations in the relevant neural circuits occur from drug addiction over a certain period. And these significant alterations are also revealed by analyzing fMRI. However, because of fMRI's high dimensionality and poor…
Glioblastoma is a common brain malignancy that tends to occur in older adults and is almost always lethal. The effectiveness of chemotherapy, being the standard treatment for most cancer types, can be improved if a particular genetic…
Neuroblastoma is a paediatric extracranial solid cancer that arises from the developing sympathetic nervous system and is characterised by an abnormal distribution of cell types in tumours compared to healthy infant tissues. In this paper,…
Starting from a two-scale description involving receptor binding dynamics and a kinetic transport equation for the evolution of the cell density function under velocity reorientations, we deduce macroscopic models for glioma invasion…
The realism of current models of the penumbra is assessed by comparing their predictions with the plasma properties of penumbral filaments as retrieved from spectropolarimetric observations. The spectropolarimeter onboard Hinode allows us…
Astrophysical plasmas can have parameters vastly different from the more studied laboratory and space plasmas. In particular, the magnetic fields can be the dominant component of the plasma, with energy-density exceeding the particle…
In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma, which includes an anisotropic nonlinear diffusion term with a diffusion velocity increasing with respect to vasculature. First, we prove the existence of…
We present efficient coupling of single organic molecules to a gallium phosphide subwavelength waveguide (nanoguide). By examining and correlating the temporal dynamics of various single-molecule resonances at different locations along the…