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Despite mass flow is arguably the most elementary transport associated to nanofluidics, its measurement still constitutes a significant bottleneck for the development of this promising field. Here, we investigate how a liquid flow perturbs…

软凝聚态物质 · 物理学 2020-01-29 Simon Gravelle , Christophe Ybert

We investigate using molecular dynamics the effect of the structure of nanoconfinement for liquids with water-like anomalies and liquid-liquid phase transition (LLPT). We find that if the confinement is in an ordered matrix of nanoparticles…

Addressing the optical properties of a single nanoparticle in the infrared is particularly challenging, thus alternative methods for characterizing the conductance spectrum of nanoparticles in this spectral range need to be developed. Here…

介观与纳米尺度物理 · 物理学 2017-10-17 Hongyue Wang , Emmanuel Lhuillier , Qian Yu , Alexandre Zimmers , Benoit Dubertret , Christian Ulysse , Hervé Aubin

We review the effects of macromolecular crowding on the folding of RNA by considering the simplest scenario when excluded volume interactions between crowding particles and RNA dominate. Using human telomerase enzyme as an example, we…

生物大分子 · 定量生物学 2013-04-17 Natalia A. Denesyuk , D. Thirumalai

Modeling the ion concentration profile in nanochannel plays an important role in understanding the electrical double layer and electroosmotic flow. Due to the non-negligible surface interaction and the effect of discrete solvent molecules,…

机器学习 · 计算机科学 2023-12-19 Zhonglin Cao , Yuyang Wang , Cooper Lorsung , Amir Barati Farimani

The performance of nanoscale electronic devices based on a two-three dimensional (2D-3D) interface is significantly affected by the electrical contacts that interconnect these materials with external circuitry. This work investigates charge…

Nanochannels provide means for detailed experiments on the effect of confinement on biomacromolecules, such as DNA. We here introduce a model for the complete unfolding of DNA from the circular to linear configuration. Two main ingredients…

Fast, reliable and inexpensive DNA sequencing is an important pursuit in healthcare, especially in personalized medicine with possible deep societal impacts. Despite significant progress of various nanopore-based sequencing configurations,…

When DNA molecules are heated they denature. This occurs locally so that loops of molten single DNA strands form, connected by intact double-stranded DNA pieces. The properties of this "melting" transition have been intensively…

生物物理 · 物理学 2015-06-29 E. Werner , M. Reiter-Schad , T. Ambjörnsson , B. Mehlig

The requirement to boost the resolution of nanopore-based biosequencing devices necessitates the integration of novel biosensing techniques with reduced sensitivity to background noise. In this article, we probe the signatures of…

软凝聚态物质 · 物理学 2023-05-01 Sahin Buyukdagli

We present microwave measurements of a high quality factor superconducting resonator incorporating two aluminum nanobridge Josephson junctions in a loop shunted by an on-chip capacitor. Trapped quasiparticles (QPs) shift the resonant…

超导电性 · 物理学 2014-03-03 E. M. Levenson-Falk , F. Kos , R. Vijay , L. Glazman , I. Siddiqi

Charge migration along DNA molecules has attracted scientific interest for over half a century. Reports on possible high rates of charge transfer between donor and acceptor through the DNA, obtained in the last decade from solution…

材料科学 · 物理学 2009-11-10 Danny Porath , Gianaurelio Cuniberti , Rosa Di Felice

We investigate the ionic current modulation in DNA nanopore translocation setups by numerically solving the electrokinetic mean-field equations for an idealized model. Specifically, we study the dependence of the ionic current on the…

软凝聚态物质 · 物理学 2021-10-13 Kai Szuttor , Patrick Kreissl , Christian Holm

DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent…

生物物理 · 物理学 2016-04-13 Bo Broadwater , Harold Kim

Ion transport in highly-confined space is important to various applications, such as biosensing and seawater desalination with nanopores. All-atom molecular dynamics simulations are conducted to investigate the transport of Na$^+$ and…

介观与纳米尺度物理 · 物理学 2019-07-30 Zhongwu Li , Yinghua Qiu , Yan Zhang , Min Yue , Yunfei Chen

Methods for reducing and directly controlling the speed of DNA through a nanopore are needed to enhance sensing performance for direct strand sequencing and detection/mapping of sequence-specific features. We have created a method for…

生物物理 · 物理学 2018-11-28 Xu Liu , Yuning Zhang , Roland Nagel , Walter Reisner , William B. Dunbar

The one-dimensional confinement of quasiparticles in individual carbon nanotubes (CNTs) leads to extremely anisotropic electronic and optical properties. In a macroscopic ensemble of randomly oriented CNTs, this anisotropy disappears…

Particles with ligand-receptor contacts bind and unbind fluctuating "legs" to surfaces, whose fluctuations cause the particle to diffuse. Quantifying the diffusion of such "nanoscale caterpillars" is a challenge, since binding events often…

软凝聚态物质 · 物理学 2022-03-21 Sophie Marbach , Jeana Aojie Zheng , Miranda Holmes-Cerfon

Quantum transport for DNA conduction has widely studied with interest in application as a candidate in making nanowires as well as interest in the scientific mechanism. In this paper, we review recent works with concerning the electronic…

无序系统与神经网络 · 物理学 2015-03-13 Hiroaki Yamada , Kazumoto Iguchi

Spatially extended aggregates of dopants are ubiquitous in a plethora of granular superconductors, forming a droplet network that is very important to their characterization and to the description of their superconducting properties. At the…

超导电性 · 物理学 2023-07-26 Victor Velasco , Marcello B. Silva Neto