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When evaluating the performance of a model for individualised risk prediction, the sample size needs to be large enough to precisely estimate the performance measures of interest. Current sample size guidance is based on precisely…

Power and sample size analysis comprises a critical component of clinical trial study design. There is an extensive collection of methods addressing this problem from diverse perspectives. The Bayesian paradigm, in particular, has attracted…

统计方法学 · 统计学 2021-12-08 Jane Pan , Sudipto Banerjee

The System Usability Scale (SUS) is a short, survey-based approach used to determine the usability of a system from an end user perspective once a prototype is available for assessment. Individual scores are gathered using a 10-question…

统计方法学 · 统计学 2021-01-26 Nicholas Clark , Matthew Dabkowski , Patrick Driscoll , Dereck Kennedy , Ian Kloo , Heidy Shi

The Partial Area Under the ROC Curve (PAUC), typically including One-way Partial AUC (OPAUC) and Two-way Partial AUC (TPAUC), measures the average performance of a binary classifier within a specific false positive rate and/or true positive…

机器学习 · 计算机科学 2022-10-12 Huiyang Shao , Qianqian Xu , Zhiyong Yang , Shilong Bao , Qingming Huang

Accurate sensor calibration is crucial for autonomous systems, yet its uncertainty quantification remains underexplored. We present the first approach to integrate uncertainty awareness into online extrinsic calibration, combining Monte…

计算机视觉与模式识别 · 计算机科学 2025-04-28 Mathieu Cocheteux , Julien Moreau , Franck Davoine

The receiver operating characteristic (ROC) curve and its summary measure, the Area Under the Curve (AUC), are well-established tools for evaluating the efficacy of biomarkers in biomedical studies. Compared to the traditional ROC curve,…

统计方法学 · 统计学 2025-10-20 Ziad Akram Ali Hammouri , Yating Zou , Rahul Ghosal , Juan C. Vidal , Marcos Matabuena

There is a growing interest in the implementation of platform trials, which provide the flexibility to incorporate new treatment arms during the trial and the ability to halt treatments early based on lack of benefit or observed…

统计方法学 · 统计学 2023-08-25 Peter Greenstreet , Thomas Jaki , Alun Bedding , Pavel Mozgunov

Deep neural networks have shown great success in prediction quality while reliable and robust uncertainty estimation remains a challenge. Predictive uncertainty supplements model predictions and enables improved functionality of downstream…

机器学习 · 计算机科学 2021-12-02 Johanna Rock , Tiago Azevedo , René de Jong , Daniel Ruiz-Muñoz , Partha Maji

We introduce two new tools to assess the validity of statistical distributions. These tools are based on components derived from a new statistical quantity, the $comparison$ $curve$. The first tool is a graphical representation of these…

统计方法学 · 统计学 2024-05-16 Gilles R. Ducharme , Teresa Ledwina

Scientists need to compare the support for models based on observed phenomena. The main goal of the evidential paradigm is to quantify the strength of evidence in the data for a reference model relative to an alternative model. This is done…

统计方法学 · 统计学 2021-03-23 Mark L. Taper , Subhash R Lele , José-Miguel Ponciano , Brian Dennis , Christopher L Jerde

Platform trials evaluate multiple experimental treatments against a common control group (and/or against each other), which often reduces the trial duration and sample size. Bayesian platform designs offer several practical advantages,…

统计方法学 · 统计学 2025-07-18 Luke Hagar , Lara Maleyeff , Shirin Golchi , Dick Menzies

Training data increasingly shapes not only model accuracy but also regulatory compliance and market valuation of AI assets. Yet existing valuation methods remain inadequate: model-based techniques depend on a single fitted model and inherit…

机器学习 · 计算机科学 2025-07-04 Jiongli Zhu , Parjanya Prajakta Prashant , Alex Cloninger , Babak Salimi

Psychiatric neuroscience is increasingly aware of the need to define psychopathology in terms of abnormal neural computation. The central tool in this endeavour is the fitting of computational models to behavioural data. The most prominent…

定量方法 · 定量生物学 2018-03-28 Abraham Nunes , Alexander Rudiuk

Monte Carlo methods, Variational Inference, and their combinations play a pivotal role in sampling from intractable probability distributions. However, current studies lack a unified evaluation framework, relying on disparate performance…

机器学习 · 计算机科学 2024-06-12 Denis Blessing , Xiaogang Jia , Johannes Esslinger , Francisco Vargas , Gerhard Neumann

Most clinical trials conducted in drug development contain multiple endpoints in order to collectively assess the intended effects of the drug on various disease characteristics. Focusing on the estimation of the global win probability,…

统计方法学 · 统计学 2024-04-09 Di Shu , Guangyong Zou

We develop tools for selective inference in the setting of group sparsity, including the construction of confidence intervals and p-values for testing selected groups of variables. Our main technical result gives the precise distribution of…

统计方法学 · 统计学 2016-07-28 Fan Yang , Rina Foygel Barber , Prateek Jain , John Lafferty

Unsupervised recalibration (URC) is a general way to improve the accuracy of an already trained probabilistic classification or regression model upon encountering new data while deployed in the field. URC does not require any ground truth…

机器学习 · 统计学 2020-10-20 Albert Ziegler , Paweł Czyż

Randomized controlled trials (RCTs) often exhibit limited inferential efficiency in estimating treatment effects due to small sample sizes. In recent years, the combination of external controls has gained increasing attention as a means of…

统计方法学 · 统计学 2025-10-06 Qinwei Yang , Jingyi Li , Peng Wu

Assessing uncertainty is an important step towards ensuring the safety and reliability of machine learning systems. Existing uncertainty estimation techniques may fail when their modeling assumptions are not met, e.g. when the data…

机器学习 · 计算机科学 2017-01-24 Volodymyr Kuleshov , Stefano Ermon

This article investigates unsupervised classification techniques for categorical multivariate data. The study employs multivariate multinomial mixture modeling, which is a type of model particularly applicable to multilocus genotypic data.…

统计理论 · 数学 2014-03-11 Dominique Bontemps , Wilson Toussile