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This study presents a computational optimisation framework of a hip implant through the development of a functionally graded biomimetic lattice structure, whose design was structurally optimised to limit stress shielding. The optimisation…

医学物理 · 物理学 2026-01-27 Mahtab Vafaeefar , Conall Quinn , Kevin M. Moerman , Ted J. Vaughan

In silico testing of implant materials is a research area of high interest, as cost- and labour-intensive experiments may be omitted. However, assessing the tissue-material interaction mathematically and computationally can be very complex,…

Triply periodic minimal surface (TPMS) structures, a type of lattice structure, have garnered significant attention due to their lightweight nature, controllability, and excellent mechanical properties. Voxel-based modeling is a widely used…

系统与控制 · 电气工程与系统科学 2025-06-05 Siqi Wang , Chuangyu Jiang , Xiaodong Zhang , Yilong Zhang , Baoqiang Zhang , Huageng Luo

While cervical arthroplasty using Total Disc Replacement (TDR) implants is an established treatment for persistent neck and arm pain, revision rates limit it from reaching its full potential. To address the underlying complications, we…

计算工程、金融与科学 · 计算机科学 2026-02-12 Lucia Kölle , Victor Oei , Ida Mónus , Syn Schmitt , Daniel Haschtmann , Fabio Galbusera , Stephen J. Ferguson , Benedikt Helgason

Triply periodic minimal surface (TPMS) metamaterials characterized by mathematically-controlled topologies exhibit better mechanical properties compared to uniform structures. The unit cell topology of such metamaterials can be further…

计算工程、金融与科学 · 计算机科学 2023-03-20 Asha Viswanath , Diab W Abueidda , Mohamad Modrek , Kamran A Khan , Seid Koric , Rashid K. Abu Al-Rub

We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…

组织与器官 · 定量生物学 2017-11-21 S. Aland , F. Stenger , R. Müller , M. Kampschulte , A. C. Langheinrich , T. El Khassawna , C. Heiß , A. Dreutsch , A. Voigt

Triply periodic minimal surfaces (TPMS) are a class of metamaterials with a variety of applications and well-known primitive morphologies. We present a new method for discovering novel microscale TPMS structures with exceptional…

Triple periodic minimal surfaces (TPMS) have garnered significant interest due to their structural efficiency and controllable geometry, making them suitable for a wide range of applications. This paper investigates the relationships…

微分几何 · 数学 2024-06-28 Sergei Ermolenko , Pavel Snopov

Triply periodic minimal surfaces (TPMSs) play a vital role in the design of porous structures, with applications in bone tissue engineering, chemical engineering, and the creation of lightweight models. However, fabrication of TPMSs via…

图形学 · 计算机科学 2024-02-20 Gao Depeng , Zhang Yuanzhi , Lin Hongwei

For their excellent stiffness-to-weight characteristics, triply periodic minimal surfaces (TPMS) are widely adopted in architected materials. However, their geometric regularity often leads to elastic anisotropy, limiting their…

计算物理 · 物理学 2025-05-21 Minwoo Park , Junheui Jo , Seunghwa Ryu

The research paper presents a novel approach to optimizing the tensile stress of Triply Periodic Minimal Surface (TPMS) structures through machine learning and Simulated Annealing (SA). The study evaluates the performance of Random Forest,…

材料科学 · 物理学 2024-06-11 Akshansh Mishra

This preliminary study focuses on the development of a medical image segmentation algorithm based on artificial intelligence for calculating bone growth in contact with metallic implants. %as a result of the problem of estimating the growth…

图像与视频处理 · 电气工程与系统科学 2022-04-25 Fernando García-Torres , Carmen Mínguez-Porter , Julia Tomás-Chenoll , Sofía Iranzo-Egea , Juan-Manuel Belda-Lois

Triply Periodic Minimal Surface (TPMS) structures have emerged as a new class of porous materials with variable geometries and favourable transport properties, making them promising for reactor internals in chemical engineering. However,…

This paper presents a density-based topology optimization method for designing 3D thin-walled structures with adaptive meshing. Uniform wall thickness is achieved by simultaneously constraining the minimum and maximum feature sizes using…

计算工程、金融与科学 · 计算机科学 2019-08-29 Yuqing Zhou , Tsuyoshi Nomura , Ercan M. Dede , Kazuhiro Saitou

Cage subsidence after instrumented lumbar spinal fusion surgery remains a significant cause of treatment failure, specifically for posterior or transforaminal lumbar interbody fusion. Recent advancements in computational techniques and…

医学物理 · 物理学 2024-06-26 Thijs Smit , Niels Aage , Daniel Haschtmann , Stephen J. Ferguson , Benedikt Helgason

- New advance technologies based on reverse engineering , design and additive manufacturing, have expanded design capabilities for biomedical applications to include Patient Specific Implants (PSI). This change in design paradigms needs…

医学物理 · 物理学 2017-09-21 J. Díaz , Octavio Andrés González-Estrada , C. López

Porous structures such as trabecular bone are widely seen in nature. These structures exhibit superior mechanical properties whilst being lightweight. In this paper, we present a method to generate bone-like porous structures as lightweight…

图形学 · 计算机科学 2018-05-01 Jun Wu , Niels Aage , Ruediger Westermann , Ole Sigmund

Functionally graded porous plates have been validated as remarkable lightweight structures with excellent mechanical characteristics and numerous applications. With inspiration from the high strength-to-volume ratio of triply periodic…

材料科学 · 物理学 2023-04-11 H. Nguyen-Xuan , Kim Q. Tran , Chien H. Thai , Jaehong Lee

Developing clinically viable tissue-engineered cardiovascular implants remains a formidable challenge. Achieving reliable and durable outcomes requires a deeper understanding of the fundamental mechanisms driving tissue evolution during in…

计算工程、金融与科学 · 计算机科学 2025-07-29 Mahmoud Sesa , Hagen Holthusen , Christian Böhm , Stefan Jockenhövel , Stefanie Reese , Kevin Linka

The aim of this paper is to develop a multiscale hierarchical hybrid model based on finite element analysis and neural network computation to link mesoscopic scale (trabecular network level) and macroscopic (whole bone level) to simulate…

医学物理 · 物理学 2011-07-20 Ridha Hambli , Abdelwahed Barkaoui
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