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Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Automatic and accurate segmentation of brain MR images throughout the human lifespan into tissue and structure is crucial for understanding brain development and diagnosing diseases. However, challenges arise from the intricate variations…

图像与视频处理 · 电气工程与系统科学 2024-08-01 Lin Teng , Zihao Zhao , Jiawei Huang , Zehong Cao , Runqi Meng , Feng Shi , Dinggang Shen

Dimensionality reduction plays an important role in computer vision problems since it reduces computational cost and is often capable of yielding more discriminative data representation. In this context, Partial Least Squares (PLS) has…

计算机视觉与模式识别 · 计算机科学 2020-11-11 Artur Jordao , Maiko Lie , Victor Hugo Cunha de Melo , William Robson Schwartz

Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Wenhao Tang , Heng Fang , Ge Wu , Xiang Li , Ming-Ming Cheng

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

图像与视频处理 · 电气工程与系统科学 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

计算机视觉与模式识别 · 计算机科学 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Medical image segmentation is critical for computer-aided diagnosis. However, dense pixel-level annotation is time-consuming and expensive, and medical datasets often exhibit severe class imbalance. Such imbalance causes minority structures…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Yingxue Su , Yiheng Zhong , Keying Zhu , Zimu Zhang , Zhuoru Zhang , Yifang Wang , Yuxin Zhang , Jingxin Liu

Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images (WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL methods primarily focus on improving the feature…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Tiancheng Lin , Zhimiao Yu , Hongyu Hu , Yi Xu , Chang Wen Chen

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Class Incremental Learning (CIL) based on pre-trained models offers a promising direction for open-world continual learning. Existing methods typically rely on correlation-based strategies, where an image's classification feature is used as…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Libo Huang , Zhulin An , Chuanguang Yang , Boyu Diao , Fei Wang , Yan Zeng , Zhifeng Hao , Yongjun Xu

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

In this paper, we propose a progressive learning paradigm for transformer-based variable-rate image compression. Our approach covers a wide range of compression rates with the assistance of the Layer-adaptive Prompt Module (LPM). Inspired…

计算机视觉与模式识别 · 计算机科学 2023-11-29 Shiyu Qin , Yimin Zhou , Jinpeng Wang , Bin Chen , Baoyi An , Tao Dai , Shu-Tao Xia

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

图像与视频处理 · 电气工程与系统科学 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Recently, images that distort or fabricate facts using generative models have become a social concern. To cope with continuous evolution of generative artificial intelligence (AI) models, model attribution (MA) is necessary beyond just…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Hanbyul Lee , Juneho Yi

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

High-resolution images are prevalent in various applications, such as autonomous driving and computer-aided diagnosis. However, training neural networks on such images is computationally challenging and easily leads to out-of-memory errors…

计算机视觉与模式识别 · 计算机科学 2023-03-08 Benjamin Bergner , Christoph Lippert , Aravindh Mahendran

Whole Slide Images (WSIs) are typically analyzed using multiple instance learning (MIL) methods. However, the scale and heterogeneity of WSIs generate highly redundant and dispersed information, making it difficult to identify and integrate…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Yueting Zhu , Yuehao Song , Shuai Zhang , Wenyu Liu , Xinggang Wang