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Supervised training a deep neural network aims to "teach" the network to mimic human visual perception that is represented by image-and-label pairs in the training data. Superpixelized (SP) images are visually perceivable to humans, but a…

计算机视觉与模式识别 · 计算机科学 2019-03-04 Yizhe Zhang , Lin Yang , Hao Zheng , Peixian Liang , Colleen Mangold , Raquel G. Loreto , David P. Hughes , Danny Z. Chen

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

计算机视觉与模式识别 · 计算机科学 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

计算机视觉与模式识别 · 计算机科学 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

In digital pathology, the multiple instance learning (MIL) strategy is widely used in the weakly supervised histopathology whole slide image (WSI) classification task where giga-pixel WSIs are only labeled at the slide level. However,…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Zhan Shi , Jingwei Zhang , Jun Kong , Fusheng Wang

Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…

图像与视频处理 · 电气工程与系统科学 2025-04-01 M Rita Verdelho , Alexandre Bernardino , Catarina Barata

Recently, lots of deep networks are proposed to improve the quality of predicted super-resolution (SR) images, due to its widespread use in several image-based fields. However, with these networks being constructed deeper and deeper, they…

计算机视觉与模式识别 · 计算机科学 2020-03-10 Wei. Lin , Junyu. Gao , Qi. Wang , Xuelong. Li

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Xiangyu Li , Ran Su

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Multiple Instance Learning (MIL) has demonstrated promise in Whole Slide Image (WSI) classification. However, a major challenge persists due to the high computational cost associated with processing these gigapixel images. Existing methods…

计算机视觉与模式识别 · 计算机科学 2023-12-05 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen

Multiple instance learning (MIL) has been widely used for representing whole-slide pathology images. However, spatial, semantic, and decision entanglements among instances limit its representation and interpretability. To address these…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Chentao Li , Behzad Bozorgtabar , Yifang Ping , Pan Huang , Jing Qin

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

Physics-driven deep learning (PD-DL) models have proven to be a powerful approach for improved reconstruction of rapid MRI scans. In order to train these models in scenarios where fully-sampled reference data is unavailable, self-supervised…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Yaşar Utku Alçalar , Mehmet Akçakaya

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

计算机视觉与模式识别 · 计算机科学 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

计算机视觉与模式识别 · 计算机科学 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Data augmentation is an effective way to improve the performance of deep networks. Unfortunately, current methods are mostly developed for high-level vision tasks (e.g., classification) and few are studied for low-level vision tasks (e.g.,…

图像与视频处理 · 电气工程与系统科学 2020-04-24 Jaejun Yoo , Namhyuk Ahn , Kyung-Ah Sohn

Interpretability of deep learning (DL) systems is gaining attention in medical imaging to increase experts' trust in the obtained predictions and facilitate their integration in clinical settings. We propose a deep visualization method to…

计算机视觉与模式识别 · 计算机科学 2022-02-02 Cristina González-Gonzalo , Bart Liefers , Bram van Ginneken , Clara I. Sánchez

Unified image restoration models for diverse and mixed degradations often suffer from unstable optimization dynamics and inter-task conflicts. This paper introduces Self-Improved Privilege Learning (SIPL), a novel paradigm that overcomes…

计算机视觉与模式识别 · 计算机科学 2025-06-02 Gang Wu , Junjun Jiang , Kui Jiang , Xianming Liu