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Background/Objectives: Age-related macular degeneration, glaucoma, diabetic retinopathy (DR), diabetic macular edema, and pathological myopia affect hundreds of millions of people worldwide. Early screening for these diseases is essential,…

图像与视频处理 · 电气工程与系统科学 2025-07-18 Ananya Raghu , Anisha Raghu , Alice S. Tang , Yannis M. Paulus , Tyson N. Kim , Tomiko T. Oskotsky

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Gastrointestinal (GI) tract image analysis plays a crucial role in medical diagnosis. This research addresses the challenge of accurately classifying and segmenting GI images for real-time applications, where traditional methods often…

图像与视频处理 · 电气工程与系统科学 2026-03-25 Zeshan Khan , Muhammad Atif Tahir

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

图像与视频处理 · 电气工程与系统科学 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system of the patient starts attacking healthy tissues of the body. Lupus Nephritis (LN) refers to the inflammation of kidney tissues resulting in renal failure…

图像与视频处理 · 电气工程与系统科学 2021-12-15 Akash Gupta , Anirudh Reddy , CV Jawahar , PK Vinod

The pathological diagnosis of gestational trophoblastic disease(GTD) takes a long time, relies heavily on the experience of pathologists, and the consistency of initial diagnosis is low, which seriously threatens maternal health and…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Yuhang Liu , Yueyang Cang , Wenge Que , Xinru Bai , Xingtong Wang , Kuisheng Chen , Jingya Li , Xiaoteng Zhang , Xinmin Li , Lixia Zhang , Pingge Hu , Qiaoting Xie , Peiyu Xu , Xianxu Zeng , Li Shi

Determining the necessity of resecting malignant polyps during colonoscopy screen is crucial for patient outcomes, yet challenging due to the time-consuming and costly nature of histopathology examination. While deep learning-based…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Ruijie Yang , Yan Zhu , Peiyao Fu , Yizhe Zhang , Zhihua Wang , Quanlin Li , Pinghong Zhou , Xian Yang , Shuo Wang

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

计算机视觉与模式识别 · 计算机科学 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

计算机视觉与模式识别 · 计算机科学 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Aims: Our Gulf War Illness (GWI) study conducts combinatorial screening of many interactive neural and humoral biomarkers in order to establish predictive, diagnostic, and therapeutic targets. We encounter obstacles at every stage of the…

计算机与社会 · 计算机科学 2021-02-19 Dimitris Floros , Mulugu V. Brahmajothi , Alexandros-Stavros Iliopoulos , Nikos Pitsianis , Xiaobai Sun

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

机器学习 · 计算机科学 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

Moving from animal models to human applications in preclinical research encompasses a broad spectrum of disciplines in medical science. A fundamental element in the development of new drugs, treatments, diagnostic methods, and in deepening…

图像与视频处理 · 电气工程与系统科学 2025-02-10 Lining Yu , Mengmeng Yin , Ruining Deng , Quan Liu , Tianyuan Yao , Can Cui , Yitian Long , Yu Wang , Yaohong Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Cervical glandular cell (GC) detection is a key step in computer-aided diagnosis for cervical adenocarcinomas screening. It is challenging to accurately recognize GCs in cervical smears in which squamous cells are the major. Widely existing…

计算机视觉与模式识别 · 计算机科学 2022-07-05 Ziquan Wei , Shenghua Cheng , Jing Cai , Shaoqun Zeng , Xiuli Liu , Zehua Wang

Powerful generative AI models of protein-ligand structure have recently been proposed, but few of these methods support both flexible protein-ligand docking and affinity estimation. Of those that do, none can directly model multiple binding…

机器学习 · 计算机科学 2025-03-25 Alex Morehead , Jianlin Cheng

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Seyed Kahaki , Alexander R. Webber , Ghada Zamzmi , Adarsh Subbaswamy , Rucha Deshpande , Aldo Badano

Lung cancer is a global and dangerous disease, and its early detection is crucial to reducing the risks of mortality. In this regard, it has been of great interest in developing a computer-aided system for pulmonary nodules detection as…

计算机视觉与模式识别 · 计算机科学 2018-07-30 Bum-Chae Kim , Jun-Sik Choi , Heung-Il Suk

Nasotracheal intubation (NTI) is a vital procedure in emergency airway management, where rapid and accurate glottis detection is essential to ensure patient safety. However, existing machine assisted visual detection systems often rely on…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Jinyu Liu , Gaoyang Zhang , Yang Zhou , Ruoyi Hao , Yang Zhang , Hongliang Ren

The incidence of gastrointestinal cancers remains significantly high, particularly in China, emphasizing the importance of accurate prognostic assessments and effective treatment strategies. Research shows a strong correlation between…

图像与视频处理 · 电气工程与系统科学 2025-03-11 Xinyu Nan , Meng He , Zifan Chen , Bin Dong , Lei Tang , Li Zhang