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It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

图像与视频处理 · 电气工程与系统科学 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Alzheimer's Disease (AD) is the most widespread neurodegenerative disease, affecting over 50 million people across the world. While its progression cannot be stopped, early and accurate diagnostic testing can drastically improve quality of…

机器学习 · 计算机科学 2021-01-11 Vishnu Ram Sampathkumar

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

计算机视觉与模式识别 · 计算机科学 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Cognitive decline due to Alzheimer's disease (AD) is closely associated with brain structure alterations captured by structural magnetic resonance imaging (sMRI). It supports the validity to develop sMRI-based univariate neurodegeneration…

计算机视觉与模式识别 · 计算机科学 2020-10-28 Gang Wang , Qunxi Dong , Jianfeng Wu , Yi Su , Kewei Chen , Qingtang Su , Xiaofeng Zhang , Jinguang Hao , Tao Yao , Li Liu , Caiming Zhang , Richard J Caselli , Eric M Reiman , Yalin Wang

Alzheimer's disease (AD) is a neuro-degenerative disease that can cause dementia and result severe reduction in brain function inhibiting simple tasks especially if no preventative care is taken. Over 1 in 9 Americans suffer from AD induced…

图像与视频处理 · 电气工程与系统科学 2023-06-21 Paul K. Mandal , Rakesh Mahto

Deep learning, a cutting-edge machine learning approach, outperforms traditional machine learning in identifying intricate structures in complex high-dimensional data, particularly in the domain of healthcare. This study focuses on…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Nida Nasir , Muneeb Ahmed , Neda Afreen , Mustafa Sameer

Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…

计算机视觉与模式识别 · 计算机科学 2024-07-12 Yihan Zhang , Xuanshuo Zhang , Wei Wu , Haohan Wang

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2017-12-21 Jyoti Islam , Yanqing Zhang

Alzheimer's Disease (AD) is a progressive neurodegenerative condition that adversely affects cognitive abilities. Language-related changes can be automatically identified through the analysis of outputs from linguistic assessment tasks,…

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Alzheimer's Disease (AD) is one of the most concerned neurodegenerative diseases. In the last decade, studies on AD diagnosis attached great significance to artificial intelligence (AI)-based diagnostic algorithms. Among the diverse…

计算机视觉与模式识别 · 计算机科学 2019-08-20 Yechong Huang , Jiahang Xu , Yuncheng Zhou , Tong Tong , Xiahai Zhuang , the Alzheimer's Disease Neuroimaging Initiative

In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution. Our approach combines a spatio-temporal description of both processes into a…

神经元与认知 · 定量生物学 2019-05-27 Raphaël Sivera , Hervé Delingette , Marco Lorenzi , Xavier Pennec , Nicholas Ayache

Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…

计算与语言 · 计算机科学 2022-07-19 Anna Hlédiková , Dominika Woszczyk , Alican Akman , Soteris Demetriou , Björn Schuller

This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano

Discriminating patients with Alzheimer's disease (AD) from healthy subjects is a crucial task in the research of Alzheimer's disease. The task can be potentially achieved by linear discriminant analysis (LDA), which is one of the most…

统计方法学 · 统计学 2020-05-05 Yingjie Li , Liangliang Zhang , Tapabrata Maiti

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, primarily affecting the elderly population and leading to significant cognitive decline. This decline manifests in various mental faculties such as attention,…

机器学习 · 计算机科学 2025-04-22 Emine Akpinar

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Alzheimer's disease (AD) is a complex, multifactorial neurodegenerative disorder with substantial heterogeneity in progression and treatment response. Despite recent therapeutic advances, predictive models capable of accurately forecasting…

机器学习 · 计算机科学 2025-07-23 Jindong Wang , Yutong Mao , Xiao Liu , Wenrui Hao