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While biomanufacturing plays a significant role in supporting the economy and ensuring public health, it faces critical challenges, including complexity, high variability, lengthy lead time, and very limited process data, especially for…

机器学习 · 统计学 2021-06-03 Wei Xie , Bo Wang , Cheng Li , Dongming Xie , Jared Auclair

Biomanufacturing plays an important role in supporting public health and the growth of the bioeconomy. Modeling and studying the interaction effects among various input variables is very critical for obtaining a scientific understanding and…

统计方法学 · 统计学 2024-11-26 Junkai Zhao , Jun Luo , Wei Xie , Zixuan Bai

We present a novel approach for explaining Gaussian processes (GPs) that can utilize the full analytical covariance structure present in GPs. Our method is based on the popular solution concept of Shapley values extended to stochastic…

机器学习 · 统计学 2023-05-25 Siu Lun Chau , Krikamol Muandet , Dino Sejdinovic

The global sensitivity analysis of a numerical model aims to quantify, by means of sensitivity indices estimate, the contributions of each uncertain input variable to the model output uncertainty. The so-called Sobol' indices, which are…

统计理论 · 数学 2019-11-26 Bertrand Iooss , Clémentine Prieur

Global sensitivity analysis of complex numerical simulators is often limited by the small number of model evaluations that can be afforded. In such settings, surrogate models built from a limited set of simulations can substantially reduce…

机器学习 · 统计学 2026-01-21 Guerlain Lambert , Céline Helbert , Claire Lauvernet

The Shapley value (SV) has emerged as a promising method for data valuation. However, computing or estimating the SV is often computationally expensive. To overcome this challenge, Jia et al. (2019) propose an advanced SV estimation…

机器学习 · 统计学 2023-02-23 Jiachen T. Wang , Ruoxi Jia

Feature attribution for kernel methods is often heuristic and not individualised for each prediction. To address this, we turn to the concept of Shapley values~(SV), a coalition game theoretical framework that has previously been applied to…

机器学习 · 统计学 2022-05-27 Siu Lun Chau , Robert Hu , Javier Gonzalez , Dino Sejdinovic

Global Sensitivity Analysis (GSA) is the study of the influence of any given inputs on the outputs of a model. In the context of engineering design, GSA has been widely used to understand both individual and collective contributions of…

机器学习 · 统计学 2024-03-06 Yigitcan Comlek , Liwei Wang , Wei Chen

The proportion of edges in a Gaussian graphical model (GGM) characterizes the complexity of its conditional dependence structure. Since edge presence corresponds to a nonzero entry of the precision matrix, estimation of this proportion can…

统计方法学 · 统计学 2026-03-05 Nabaneet Das , Thorsten Dickhaus

Shapley values have seen widespread use in machine learning as a way to explain model predictions and estimate the importance of covariates. Accurately explaining models is critical in real-world models to both aid in decision making and to…

机器学习 · 统计学 2024-08-19 Daniel de Marchi , Michael Kosorok , Scott de Marchi

Risk scores are widely used for clinical decision making and commonly generated from logistic regression models. Machine-learning-based methods may work well for identifying important predictors, but such 'black box' variable selection…

机器学习 · 计算机科学 2024-12-31 Yilin Ning , Siqi Li , Marcus Eng Hock Ong , Feng Xie , Bibhas Chakraborty , Daniel Shu Wei Ting , Nan Liu

Variance-based sensitivity methods can provide insights into large computational models. We present a novel application of sensitivity analysis to the Biomass Scenario Model (BSM) a large and complex system dynamics model of the developing…

应用统计 · 统计学 2018-03-29 Daniel Inman , Laura J. Vimmerstedt , Brian Bush , Dana Stright , Steve Peterson

Understanding the dynamics and evolution of climate change and associated uncertainties is key for designing robust policy actions. Computer models are key tools in this scientific effort, which have now reached a high level of…

统计方法学 · 统计学 2024-04-30 Matteo Fontana , Massimo Tavoni , Simone Vantini

Shapley effects are attracting increasing attention as sensitivity measures. When the value function is the conditional variance, they account for the individual and higher order effects of a model input. They are also well defined under…

统计计算 · 统计学 2021-10-13 Elmar Plischke , Giovanni Rabitti , Emanuele Borgonovo

Graphical models are ubiquitous tools to describe the interdependence between variables measured simultaneously such as large-scale gene or protein expression data. Gaussian graphical models (GGMs) are well-established tools for…

统计方法学 · 统计学 2020-01-09 Nilabja Guha , Veera Baladandayuthapani , Bani K. Mallick

High-dimensional Bayesian optimization (BO) tasks such as molecular design often require 10,000 function evaluations before obtaining meaningful results. While methods like sparse variational Gaussian processes (SVGPs) reduce computational…

机器学习 · 计算机科学 2025-06-11 Natalie Maus , Kyurae Kim , Geoff Pleiss , David Eriksson , John P. Cunningham , Jacob R. Gardner

High-fidelity simulations and physical experiments are essential for engineering analysis and design, yet their high cost often makes two critical tasks--global sensitivity analysis (GSA) and optimization--prohibitively expensive. This…

机器学习 · 计算机科学 2026-01-01 Bach Do , Nafeezat A. Ajenifuja , Taiwo A. Adebiyi , Ruda Zhang

Global sensitivity analysis aims at measuring the relative importance of different variables or groups of variables for the variability of a quantity of interest. Among several sensitivity indices, so-called Shapley effects have recently…

统计计算 · 统计学 2021-04-27 Takashi Goda

Parameter sensitivity analysis is a powerful tool in the building and analysis of biochemical network models. For stochastic simulations, parameter sensitivity analysis can be computationally expensive, requiring multiple simulations for…

计算物理 · 物理学 2015-06-04 Patrick B. Warren , Rosalind J. Allen

The Tactile Internet (TI) requires ultra-low latency and reliable haptic signal transmission, yet packet loss and delay remain unresolved challenges. We present a novel prediction framework that integrates Gaussian Processes (GP) with a…

信号处理 · 电气工程与系统科学 2026-01-27 Mohammad Ali Vahedifar , Qi Zhang
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