相关论文: Using sequence data to study spatial scales of int…
Highly pathogenic avian influenza (HPAI), especially the H5N1 strain, remains a major threat to animal health, food security, and public health. Recent spillover events in dairy cattle in the United States, linked to wild birds, highlight…
Highly pathogenic avian influenza (HPAI) has expanded its host range with recent detections in dairy cattle, raising critical concerns regarding within-herd persistence and cross-species spillover. This study develops a stochastic…
The highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b has triggered an unprecedented global panzootic. As the frequency and scale of HPAI H5 outbreaks continue to rise, understanding how wild birds contribute to shape the global…
One Health issues, such as the spread of highly pathogenic avian influenza~(HPAI), present significant challenges at the human-animal-environmental interface. Recent H5N1 outbreaks underscore the need for comprehensive modeling efforts that…
Global mobility flow data are at the heart of spatial epidemiological models used to predict infectious disease behavior but this wealth of data on human mobility has been largely neglected by reconstructions of pathogen evolutionary…
Highly pathogenic avian influenza A(H5N1) has expanded geographically and ecologically, affecting wild birds, mammalian wildlife, domestic animals, and humans. Wildlife surveillance provides critical early warning for One Health…
Community science observational datasets are useful in epidemiology and ecology for modeling species distributions, but the heterogeneous nature of the data presents significant challenges for standardization, data quality assurance and…
Confirmed cases during the early stage of the 2009 H1N1 pdm in various countries showed an age shift between importations and local transmission cases, with adults mainly responsible for seeding unaffected regions and children most…
Background: The pandemic of influenza A (H1N1) is a serious on-going global public crisis. Understanding its spreading dynamics is of fundamental importance for both public health and scientific researches. Recent studies have focused…
Since early 2024, highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.3.4.4b has spilled over from wild birds to dairy cattle in the United States (U.S.), spreading to more than 1000 herds and threatening both animal and public…
Pathogen genome data offers valuable structure for spatial models, but its utility is limited by incomplete sequencing coverage. We propose a probabilistic framework for inferring genetic distances between unsequenced cases and known…
Accurate forecasting of avian disease outbreaks is critical for wildlife conservation and public health. This study presents a Transformer-based framework for predicting the disease risk at the terminal locations of migratory bird…
Accurate forecasting of Avian Influenza Virus (AIV) outbreaks within wild bird populations necessitates models that account for complex, multi-scale transmission patterns driven by diverse factors. While conventional spatiotemporal epidemic…
The rapid spread of the HPAI H5N1 virus, responsible for the Avian Flu, is causing a great catastrophe on the South American Pacific coast (especially in the south of Peru and north of Chile). Although very little attention has been…
Estimating population-level prevalence and transmission dynamics of wildlife pathogens can be challenging, partly because surveillance data is sparse, detection-driven, and unevenly sequenced. Using highly pathogenic avian influenza A/H5…
The evolutionary dynamics of human Influenza A virus presents a challenging theoretical problem. An extremely high mutation rate allows the virus to escape, at each epidemic season, the host immune protection elicited by previous…
Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between…
Disease outbreaks, such as those of Severe Acute Respiratory Syndrome in 2003 and the 2009 pandemic A(H1N1) influenza, have highlighted the potential for airborne transmission in indoor environments. Respirable pathogen-carrying droplets…
Infectious diseases on farms pose both public and animal health risks, so understanding how they spread between farms is crucial for developing disease control strategies to prevent future outbreaks. We develop novel Bayesian nonparametric…
Zoonotic disease transmission between animals and humans is a growing risk and the agricultural context acts as a likely point of transition, with individual heterogeneity acting as an important contributor. Thus, understanding the dynamics…