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Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

神经元与认知 · 定量生物学 2011-08-01 Christian Kuehn , Christian Meisel

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

系统与控制 · 电气工程与系统科学 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven

There is a ongoing debate whether generic early warning signals for critical transitions exist that can be applied across diverse systems. The human epileptic brain is often considered as a prototypical system, given the devastating and, at…

医学物理 · 物理学 2019-10-23 Theresa Wilkat , Thorsten Rings , Klaus Lehnertz

Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…

神经元与认知 · 定量生物学 2021-01-27 Elif Köksal Ersöz , Julien Modolo , Fabrice Bartolomei , Fabrice Wendling

Epilepsy is a well-known neuronal disorder that can be identified by interpretation of the electroencephalogram (EEG) signal. Usually, the length of an EEG signal is quite long which is challenging to interpret manually. In this work, we…

机器学习 · 计算机科学 2019-03-07 Md Mursalin , Syed Shamsul Islam , Md Kislu Noman , Adel Ali Al-Jumaily

Epilepsy is a disease in which frequent seizures occur due to abnormal activity of neurons. Patients affected by this disease can be treated with the help of medicines or surgical procedures. However, both of these methods are not quite…

神经元与认知 · 定量生物学 2020-04-20 Syed Muhammad Usman , Shahzad Latif , Arshad Beg

There is growing interest in anticipating critical transitions in natural systems, often pursued through statistical detection of early warning signals associated with dynamical bifurcations. In stochastic dynamical systems, such signals…

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

神经元与认知 · 定量生物学 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

机器学习 · 计算机科学 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…

定量方法 · 定量生物学 2025-12-25 Yaoyue Wang , Arian Ashourvan , Guilherme Ramos , Paul Bogdan , Emily Pereira

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

神经元与认知 · 定量生物学 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Epilepsy is a common disease of the nervous system. Timely prediction of seizures and intervention treatment can significantly reduce the accidental injury of patients and protect the life and health of patients. This paper presents a…

信号处理 · 电气工程与系统科学 2024-10-01 Qinyu Chen , Congyi Sun , Chang Gao , Shih-Chii Liu

The use of critical slowing down as an early warning indicator for regime switching in observations from stochastic environments and noisy dynamical models has been widely studied and implemented in recent years. Some systems, however, have…

动力系统 · 数学 2019-01-25 Mathew Titus , Zach Gelbaum , James Watson

Abrupt shifts in ecosystems, brains, markets, and climate are often diagnosed as signs of approaching a tipping point, i.e. a critical bifurcation where stability is lost. Here we reveal a broader and more deceptive mechanism:…

混沌动力学 · 物理学 2025-10-06 Virgile Troude , Sandro Claudio Lera , Ke Wu , Didier Sornette

We study a two-dimensional low-dissipation dynamical system with a control parameter that is swept linearly in time across a transcritical bifurcation. We investigate the relaxation time of a perturbation applied to a variable of the system…

斑图形成与孤子 · 物理学 2020-09-30 M. Marconi , C. Metayer , A. Acquaviva , J. M. Boyer , A. Gomel , T. Quiniou , C. Masoller , M. Giudici , J. R. Tredicce

Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…

定量方法 · 定量生物学 2024-06-17 Ximena Fernández , Diego Mateos

Epilepsy is one of the most common and yet diverse set of chronic neurological disorders. This excessive or synchronous neuronal activity is termed seizure. Electroencephalogram signal processing plays a significant role in detection and…

信号处理 · 电气工程与系统科学 2021-09-29 Paul Grant , Md Zahidul Islam

An epileptic seizure is a transient event of abnormal excessive neuronal discharge in the brain. This unwanted event can be obstructed by detection of electrical changes in the brain that happen before the seizure takes place. The automatic…

机器学习 · 计算机科学 2016-04-29 Z. Roshan Zamir

Although a seizure event represents a major deviation from a baseline electroencephalographic signal, there are features of seizure morphology that can be seen in non-epileptic portions of the record. A transient decrease in frequency,…

信号处理 · 电气工程与系统科学 2018-01-09 Eva von Weltin , Tameem Ahsan , Vinit Shah , Dawer Jamshed , Meysam Golmohammadi , Iyad Obeid , Joseph Picone

Changes in the statistical properties of a stochastic process are typically assumed to occur via change-points, which demark instantaneous moments of complete and total change in process behavior. In cases where these transitions occur…

机器学习 · 统计学 2022-05-06 Chris Browne
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