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As Large Language Models (LLMs) continue to be increasingly applied across various domains, their widespread adoption necessitates rigorous monitoring to prevent unintended negative consequences and ensure robustness. Furthermore, LLMs must…

计算与语言 · 计算机科学 2025-07-09 Seshu Tirupathi , Dhaval Salwala , Elizabeth Daly , Inge Vejsbjerg

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

信息检索 · 计算机科学 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Large language models (LLMs) have been widely deployed as autonomous agents capable of following user instructions and making decisions in real-world applications. Previous studies have made notable progress in benchmarking the instruction…

计算与语言 · 计算机科学 2025-06-18 Lingxiao Diao , Xinyue Xu , Wanxuan Sun , Cheng Yang , Zhuosheng Zhang

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…

人工智能 · 计算机科学 2024-10-15 Abhishek Dutta , Yen-Che Hsiao

Medical decision-making is a critical task, where errors can result in serious, potentially life-threatening consequences. While full automation remains challenging, hybrid frameworks that combine machine intelligence with human oversight…

人工智能 · 计算机科学 2025-09-10 Debodeep Banerjee , Burcu Sayin , Stefano Teso , Andrea Passerini

As Large Language Models (LLMs) become increasingly integral to various domains, their potential to generate harmful responses has prompted significant societal and regulatory concerns. In response, governments have issued ethics guidelines…

计算与语言 · 计算机科学 2026-05-12 Haibo Jin , Ruoxi Chen , Peiyan Zhang , Andy Zhou , Zelei Cheng , Haohan Wang

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules. While machine-learning models achieve strong performance, many fail to translate…

机器学习 · 计算机科学 2026-05-25 Silas Ruhrberg Estévez , Christopher Chiu , Mihaela van der Schaar

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Despite being empowered with alignment mechanisms, large language models (LLMs) are increasingly vulnerable to emerging jailbreak attacks that can compromise their alignment mechanisms. This vulnerability poses significant risks to…

计算与语言 · 计算机科学 2025-04-15 Shaoqing Zhang , Zhuosheng Zhang , Kehai Chen , Rongxiang Weng , Muyun Yang , Tiejun Zhao , Min Zhang

This research examines the use of Reinforcement Learning from AI Feedback (RLAIF) techniques to improve healthcare dialogue models, with the aim of tackling the challenges of preference-aligned data annotation while reducing the reliance on…

计算与语言 · 计算机科学 2024-10-08 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized…

Mental health disorders affect millions worldwide, and healthcare systems are increasingly overwhelmed by the volume of clinical data generated from electronic records, telemedicine platforms, and population-level screening programs. At the…

人工智能 · 计算机科学 2026-05-14 Giuliano Lorenzoni , Paulo Alencar , Donald Cowan

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

人机交互 · 计算机科学 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Clinical patient notes are critical for documenting patient interactions, diagnoses, and treatment plans in medical practice. Ensuring accurate evaluation of these notes is essential for medical education and certification. However, manual…

计算与语言 · 计算机科学 2024-01-25 Jingyu Xu , Yifeng Jiang , Bin Yuan , Shulin Li , Tianbo Song

The integration of tool use into large language models (LLMs) enables agentic systems with real-world impact. In the meantime, unlike standalone LLMs, compromised agents can execute malicious workflows with more consequential impact,…

密码学与安全 · 计算机科学 2025-02-17 Jizhou Chen , Samuel Lee Cong

Proprietary Large Language Models (LLMs) such as GPT-4 and Gemini have demonstrated promising capabilities in clinical text summarization tasks. However, due to patient data privacy concerns and computational costs, many healthcare…

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

As Large Language Models (LLMs) are increasingly deployed as task-oriented agents in enterprise environments, ensuring their strict adherence to complex, domain-specific operational guidelines is critical. While utilizing an LLM-as-a-Judge…

计算与语言 · 计算机科学 2026-04-15 Jingbo Yang , Guanyu Yao , Bairu Hou , Xinghan Yang , Nikolai Glushnev , Iwona Bialynicka-Birula , Duo Ding , Shiyu Chang

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

机器学习 · 计算机科学 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani
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