相关论文: Extended one-dimensional reduced model for blood f…
We describe a one-dimensional (1D) unsteady and viscous flow model that is derived from the momentum and mass conservation equations, and to enhance this physics-based model, we use a machine learning approach to determine the unknown…
Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…
Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…
The nonlinear inviscid 1D blood flow equations are studied analytically using the method of characteristics. The boundary value problem with a triangle-shaped boundary data at the aortic outlet is considered. The pressure-velocity profile,…
Background and Objective: This study aims to evaluate the dynamic effect of non-Newtonian cerebral arterial circulation on electrical conductivity distribution (ECD) in a realistic multi-compartment head model. It addresses the importance…
Among cardiovascular diseases, atherosclerosis is a primary cause of stenosis, involving the accumulation of plaques in the inner lining of an artery. Inspired by drug delivery applications, the proposed study aims to examine the numerical…
We consider an optimal flow control problem in a patient-specific coronary artery bypass graft with the aim of matching the blood flow velocity with given measurements as the Reynolds number varies in a physiological range. Blood flow is…
We present a generalizable uncertainty quantification (UQ) and visualization framework for lattice Boltzmann method simulations of high Reynolds number vascular flows, demonstrated on a patient-specific stenosed aorta. The framework…
Some existing models of the atherosclerosis development are discussed and a new improved mathematical model, which takes into account new experimental results about diverse roles of macrophages in atherosclerosis, is proposed. Using technic…
This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…
Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…
Two aspects of a widely used 1D model of blood flow in a single blood vessel are studied by symmetry analysis, where the variables in the model are the blood pressure and the cross-section area of the blood vessel. As one main result, all…
Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…
Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…
The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected…
A finite element analysis of flows of an Oldroyd-B fluid is developed, to simulate blood flow in an arteriovenous fistula. The model uses a combination of a standard conforming finite element approximation for the momentum equation, and the…
Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like…
We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…
The discretization of reduced one-dimensional hyperbolic models of blood flow using the Lax-Friedrichs method is discussed. Employing the well-established central scheme in this domain significantly simplifies the implementation of specific…
Physics-based 0D reduced-order models provide computationally lightweight predictions of cardiovascular flows, resolving bulk hemodynamics in fractions of a second that would take days to solve using traditional 3D finite-element…