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相关论文: GP-GPT: Large Language Model for Gene-Phenotype Ma…

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Graphs are an essential data structure utilized to represent relationships in real-world scenarios. Prior research has established that Graph Neural Networks (GNNs) deliver impressive outcomes in graph-centric tasks, such as link prediction…

机器学习 · 计算机科学 2024-09-12 Xubin Ren , Jiabin Tang , Dawei Yin , Nitesh Chawla , Chao Huang

Large Language Models (LLMs), such as GPT, are considered to learn the latent distributions within large-scale web-crawl datasets and accomplish natural language processing (NLP) tasks by predicting the next token. However, this mechanism…

计算与语言 · 计算机科学 2025-02-04 Kun-Peng Ning , Jia-Yu Yao , Yu-Yang Liu , Mu-Nan Ning , Li Yuan

IMPORTANCE The response effectiveness of different large language models (LLMs) and various individuals, including medical students, graduate students, and practicing physicians, in pediatric ophthalmology consultations, has not been…

计算与语言 · 计算机科学 2023-11-09 Jason Holmes , Rui Peng , Yiwei Li , Jinyu Hu , Zhengliang Liu , Zihao Wu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

计算与语言 · 计算机科学 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

计算与语言 · 计算机科学 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes

Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks, with their performance heavily dependent on the quality of input prompts. While prompt engineering has proven effective, it typically relies on…

神经与进化计算 · 计算机科学 2025-04-17 Xavier Sécheresse , Jacques-Yves Guilbert--Ly , Antoine Villedieu de Torcy

Artificial intelligence is making spectacular progress, and one of the best examples is the development of large language models (LLMs) such as OpenAI's GPT series. In these lectures, written for readers with a background in mathematics or…

计算与语言 · 计算机科学 2023-10-09 Michael R. Douglas

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

计算与语言 · 计算机科学 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

Large Language models (LLMs), such as ChatGPT, have gained popularity in recent years with the advancement of Natural Language Processing (NLP), with use cases spanning many disciplines and daily lives as well. LLMs inherit explicit and…

计算与语言 · 计算机科学 2025-12-01 Fatima Kazi

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…

Large language models (LLMs) are raging over the medical domain, and their momentum has carried over into the mental health domain, leading to the emergence of few mental health LLMs. Although such mental health LLMs could provide…

人工智能 · 计算机科学 2024-06-25 Chenyu Ren , Yazhou Zhang , Daihai He , Jing Qin

Machine learning has revolutionized polymer science by enabling rapid property prediction and generative design. Large language models (LLMs) offer further opportunities in polymer informatics by simplifying workflows that traditionally…

计算工程、金融与科学 · 计算机科学 2026-02-20 Sonakshi Gupta , Akhlak Mahmood , Shivank Shukla , Rampi Ramprasad

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

定量方法 · 定量生物学 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Self-supervised training of language models (LMs) has seen great success for protein sequences in learning meaningful representations and for generative drug design. Most protein LMs are based on the Transformer architecture trained on…

生物大分子 · 定量生物学 2025-04-03 Yingheng Wang , Zichen Wang , Gil Sadeh , Luca Zancato , Alessandro Achille , George Karypis , Huzefa Rangwala

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

人工智能 · 计算机科学 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

Pre-trained large language models (PLMs) underlie most new developments in natural language processing. They have shifted the field from application-specific model pipelines to a single model that is adapted to a wide range of tasks.…

计算与语言 · 计算机科学 2023-06-30 Joshua Maynez , Priyanka Agrawal , Sebastian Gehrmann

Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

人工智能 · 计算机科学 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

计算与语言 · 计算机科学 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen
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