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Haemodynamic indices derived from Computational Fluid Dynamics (CFD), such as Time-averaged Wall Shear Stress (TAWSS) and Oscillatory Shear Index (OSI), are closely associated with restenosis risk in Peripheral Arterial Disease (PAD).…

The complexity of the cardiovascular system needs to be accurately reproduced in order to promptly acknowledge health conditions; to this aim, advanced multifidelity and multiphysics numerical models are crucial. On one side, Full Order…

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

Reduced-order models (ROMs) allow for the simulation of blood flow in patient-specific vasculatures without the high computational cost and wait time associated with traditional computational fluid dynamics (CFD) models. Unfortunately, due…

计算工程、金融与科学 · 计算机科学 2024-02-27 Natalia L. Rubio , Luca Pegolotti , Martin R. Pfaller , Eric F. Darve , Alison L. Marsden

Computational fluid dynamics (CFD) is a valuable asset for patient-specific cardiovascular-disease diagnosis and prognosis, but its high computational demands hamper its adoption in practice. Machine-learning methods that estimate blood…

机器学习 · 计算机科学 2024-06-18 Julian Suk , Pim de Haan , Phillip Lippe , Christoph Brune , Jelmer M. Wolterink

The numerical treatment of fluid-particle systems is a very challenging problem because of the complex coupling phenomena occurring between the two phases. Although accurate mathematical modelling is available to address this kind of…

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Computational fluid dynamics (CFD) is a valuable tool for personalised, non-invasive evaluation of hemodynamics in arteries, but its complexity and time-consuming nature prohibit large-scale use in practice. Recently, the use of deep…

机器学习 · 计算机科学 2022-01-21 Julian Suk , Pim de Haan , Phillip Lippe , Christoph Brune , Jelmer M. Wolterink

The investigation of fluid-solid systems is very important in a lot of industrial processes. From a computational point of view, the simulation of such systems is very expensive, especially when a huge number of parametric configurations…

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

流体动力学 · 物理学 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

Reduced Order Modelling (ROM) has been widely used to create lower order, computationally inexpensive representations of higher-order dynamical systems. Using these representations, ROMs can efficiently model flow fields while using…

流体动力学 · 物理学 2021-10-13 Pranshu Pant , Ruchit Doshi , Pranav Bahl , Amir Barati Farimani

This paper deals with the development of a Reduced-Order Model (ROM) to investigate haemodynamics in cardiovascular applications. It employs the use of Proper Orthogonal Decomposition (POD) for the computation of the basis functions and the…

Simulating fluid flows in different virtual scenarios is of key importance in engineering applications. However, high-fidelity, full-order models relying, e.g., on the finite element method, are unaffordable whenever fluid flows must be…

流体动力学 · 物理学 2021-11-24 Stefania Fresca , Andrea Manzoni

Three-dimensional (3D) finite-element simulations of cardiovascular flows provide high-fidelity predictions to support cardiovascular medicine, but their high computational cost limits clinical practicality. Reduced-order models (ROMs)…

计算工程、金融与科学 · 计算机科学 2025-09-01 Natalia L. Rubio , Eric F. Darve , Alison L. Marsden

Digital twins have emerged as a key technology for optimizing the performance of engineering products and systems. High-fidelity numerical simulations constitute the backbone of engineering design, providing an accurate insight into the…

机器学习 · 计算机科学 2023-06-28 G. I. Drakoulas , T. V. Gortsas , G. C. Bourantas , V. N. Burganos , D. Polyzos

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

机器学习 · 计算机科学 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Reduced order modeling (ROM) techniques are numerical methods that approximate the solution of parametric partial differential equation (PDE) by properly combining the high-fidelity solutions of the problem obtained for several…

This study presents an artificial neural network and proper orthogonal decomposition (POD)-based reduced-order model (ROM) of turbulent flow around a finite wall-mounted square cylinder. The proposed model is suitable for turbulent wake…

流体动力学 · 物理学 2021-09-21 Mustafa Z. Yousif , Hee Chang Lim

Accurate modeling of the complex dynamics of fluid flows is a fundamental challenge in computational physics and engineering. This study presents an innovative integration of High-Order Singular Value Decomposition (HOSVD) with Long…

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