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Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

应用统计 · 统计学 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

This is part of a series of weekly influenza forecasts made during the 2012-2013 influenza season. Here we present results of forecasts initiated following assimilation of observations for Week 1 (i.e. the forecast begins January 6, 2013)…

种群与进化 · 定量生物学 2013-01-22 Jeffrey Shaman , Alicia Karspeck , Marc Lipsitch

Early detection and modeling of a contagious epidemic can provide important guidance about quelling the contagion, controlling its spread, or the effective design of countermeasures. A topic of recent interest has been to design social…

Influenza poses a significant threat to public health, particularly among the elderly, young children, and people with underlying dis-eases. The manifestation of severe conditions, such as pneumonia, highlights the importance of preventing…

机器学习 · 计算机科学 2024-02-23 Yanhua Xu , Dominik Wojtczak

The impact of climate conditions on influenza epidemiology has mostly been studied by addressing a singular aspect of transmission and a climate variable correlating to it. As climate change unfolds at an unprecedented rate, we urgently…

定量方法 · 定量生物学 2025-01-24 Branislava Lalic , Vladimir Koci , Ana Firanj Sremac , Zorana Jovanovic Andersen

Pandemics have the potential to cause immense disruption and damage to communities and societies. In this paper, we model the Influenza Pandemic of 2009. We propose a hybrid model to determine how the pandemic spreads through the world. The…

种群与进化 · 定量生物学 2010-06-02 Teruhiko Yoneyama , Mukkai S. Krishnamoorthy

Evidence-based knowledge of infectious disease burden, including prevalence, incidence, severity and transmission, in different population strata and locations, and possibly in real time, is crucial to the planning and evaluation of public…

统计方法学 · 统计学 2018-08-14 Daniela De Angelis , Anne M. Presanis

Increased availability of epidemiological data, novel digital data streams, and the rise of powerful machine learning approaches have generated a surge of research activity on real-time epidemic forecast systems. In this paper, we propose…

Global mobility flow data are at the heart of spatial epidemiological models used to predict infectious disease behavior but this wealth of data on human mobility has been largely neglected by reconstructions of pathogen evolutionary…

A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

The Influenza type A virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Haemagglutinin (HA) gene of the virus has the potential to be a target for…

定量方法 · 定量生物学 2021-02-16 Charalambos Chrysostomou , Harris Partaourides , Huseyin Seker

In this manuscript, we use meteorological information in Galicia (Spain) to propose a novel approach to predict the incidence of influenza. Our approach extends the GLS methods in the multivariate framework to functional regression models…

Although advances in brain surgery techniques have led to fewer postoperative complications requiring Intensive Care Unit (ICU) monitoring, the routine transfer of patients to the ICU remains the clinical standard, despite its high cost.…

图像与视频处理 · 电气工程与系统科学 2024-12-23 Maximilian Fischer , Florian M. Hauptmann , Robin Peretzke , Paul Naser , Peter Neher , Jan-Oliver Neumann , Klaus Maier-Hein

We provide a brief technical description of an online platform for disease monitoring, titled as the Flu Detector (fludetector.cs.ucl.ac.uk). Flu Detector, in its current version (v.0.5), uses either Twitter or Google search data in…

人工智能 · 计算机科学 2016-12-19 Vasileios Lampos

There is a constant need for many healthcare programs to timely address problems with infection prevention and control (IP&C). For example, pathogens can be transmitted among patients with cystic fibrosis (CF) in both the inpatient and…

统计方法学 · 统计学 2022-07-27 Xiaotong Jiang , William Stoudemire , Marianne S. Muhlebach , Michael R. Kosorok

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

机器学习 · 计算机科学 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

While digital trace data from sources like search engines hold enormous potential for tracking and understanding human behavior, these streams of data lack information about the actual experiences of those individuals generating the data.…

The seasonality of respiratory diseases (common cold, influenza, etc.) is a well-known phenomenon studied from ancient times. The development of predictive models is still not only an actual unsolved problem of mathematical epidemiology but…

种群与进化 · 定量生物学 2014-04-28 Eugene B. Postnikov , Dmitry V. Tatarenkov

This paper presents a state estimation-based robust optimal control strategy for influenza epidemics in an interactive human society in the presence of modeling uncertainties. Interactive society is influenced by the random entrance of…

系统与控制 · 电气工程与系统科学 2020-11-12 Vahid Azimi , Mojtaba Sharifi , Seyed Fakoorian , Thang Tien Nguyen , Van Van Huynh

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

社会与信息网络 · 计算机科学 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov