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Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

图像与视频处理 · 电气工程与系统科学 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease; yet its currently available treatments are limited to stopping disease progression. Moreover, effectiveness of these treatments is not guaranteed due to the…

机器学习 · 计算机科学 2024-02-02 Diego Machado Reyes , Hanqing Chao , Juergen Hahn , Li Shen , Pingkun Yan

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

定量方法 · 定量生物学 2018-08-07 Mayssa Soussia , Islem Rekik

Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through…

In recent years, the number of papers on Alzheimer's disease classification has increased dramatically, generating interesting methodological ideas on the use machine learning and feature extraction methods. However, practical impact is…

Depression is a common mental disorder that affects millions of people worldwide. Although promising, current multimodal methods hinge on aligned or aggregated multimodal fusion, suffering two significant limitations: (i) inefficient…

计算机与社会 · 计算机科学 2024-09-25 Jiaxin Ye , Junping Zhang , Hongming Shan

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Alzheimer's disease (AD) is the most common age-related dementia. Mild cognitive impairment (MCI) is the early stage of cognitive decline before AD. It is crucial to predict the MCI-to-AD conversion for precise management, which remains…

图像与视频处理 · 电气工程与系统科学 2022-03-10 Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb , Chao Li

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

音频与语音处理 · 电气工程与系统科学 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

计算机视觉与模式识别 · 计算机科学 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Increasing effort in brain image analysis has been dedicated to early diagnosis of Alzheimer's disease (AD) based on neuroimaging data. Most existing studies have been focusing on binary classification problems, e.g., distinguishing AD…

计算机视觉与模式识别 · 计算机科学 2017-09-14 Hongming Li , Mohamad Habes , Yong Fan

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

计算与语言 · 计算机科学 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

机器学习 · 计算机科学 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Convolutional neural networks and Transformer have made significant progresses in multi-modality medical image super-resolution. However, these methods either have a fixed receptive field for local learning or significant computational…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Zexin Ji , Beiji Zou , Xiaoyan Kui , Sebastien Thureau , Su Ruan

Alzheimer's disease (AD) is one the main causes of dementia in the world and the patients develop severe disability and sometime full dependence. In previous stages Mild Cognitive Impairment (MCI) produces cognitive loss but not severe…

Alzheimer's Disease (AD) is an irreversible neurodegenerative disorder affecting millions of individuals today. The prognosis of the disease solely depends on treating symptoms as they arise and proper caregiving, as there are no current…

图像与视频处理 · 电气工程与系统科学 2024-12-17 Prayas Sanyal , Srinjay Mukherjee , Arkapravo Das , Anindya Sen

The current clinical diagnosis framework of Alzheimer's disease (AD) involves multiple modalities acquired from multiple diagnosis stages, each with distinct usage and cost. Previous AD diagnosis research has predominantly focused on how to…

计算机视觉与模式识别 · 计算机科学 2024-07-29 Yuxiao Liu , Mianxin Liu , Yuanwang Zhang , Kaicong Sun , Dinggang Shen

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

神经元与认知 · 定量生物学 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim