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A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

生物物理 · 物理学 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Mechanical interactions between biological cells may be mediated by secreted products, making them dependent on the local particle density. Here, we explore the generic physics of density-dependent attractive interactions. We show using…

软凝聚态物质 · 物理学 2017-11-29 Gavin Melaugh , Davide Marenduzzo , Alexander Morozov , Rosalind J. Allen

Active particles under soft confinement such as droplets or vesicles present intriguing phenomena, as collective motion emerges alongside the deformation of the environment. A model is employed to systematically investigate droplet…

软凝聚态物质 · 物理学 2024-07-25 Javier Diaz , Ignacio Pagonabarraga

Microswimmers often exhibit surprising patterns due to the nonequilibrium nature of their dynamics. Collectively, suspensions of microswimmers appear as a liquid whose properties set it apart from its passive counterpart. To understand the…

软凝聚态物质 · 物理学 2019-05-22 Fabian Jan Schwarzendahl , Marco G. Mazza

We set up a mesoscopic theory for interacting Brownian particles embedded in a nonequilibrium environment, starting from the microscopic interacting many-body theory. Using nonequilibrium linear response theory, we characterize the…

统计力学 · 物理学 2017-01-04 Stefano Steffenoni , Klaus Kroy , Gianmaria Falasco

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

We use computer simulations to test a simple idea for mapping between long-time self diffusivities obtained from molecular and Brownian dynamics. The strategy we explore is motivated by the behavior of fluids comprising particles that…

软凝聚态物质 · 物理学 2011-10-25 Mark J. Pond , Jeffrey R. Errington , Thomas M. Truskett

Molecular dynamics simulations have been performed on pure liquid water, aqueous solutions of sodium chloride, and polymer solutions exposed to a strong external electric field with the goal to gain molecular insight into the structural…

软凝聚态物质 · 物理学 2016-08-08 I. Nezbeda , J. Jirsák , F. Moučka , W. R. Smith

The field of active matter, and particularly active emulsions, is growing rapidly, with significant progress made recently on both theoretical and experimental fronts. Here, we summarize experimental research progress related to active…

软凝聚态物质 · 物理学 2022-10-21 Samuel Birrer , Seong Ik Cheon , Lauren D. Zarzar

The theoretical understanding of active matter, which is driven out of equilibrium by directed motion, is still fragmental and model oriented. Stochastic thermodynamics, on the other hand, is a comprehensive theoretical framework for driven…

统计力学 · 物理学 2017-01-05 Thomas Speck

We model a binary mixture of passive and active Brownian particles in two dimensions using the effective interaction between passive particles in the active bath. The activity of active particles and the size ratio of two types of particles…

软凝聚态物质 · 物理学 2022-06-15 Jay Prakash Singh , Sudipta Pattanayak , Shradha Mishra , Jaydeb Chakrabarti

Understanding the complexity of fragmentation processes is essential for regulating intercellular communication in mechanistic biology and developing novel bottom-up approaches in a large range of multiphase flow processes. In this context,…

介观与纳米尺度物理 · 物理学 2019-05-09 François Sicard , Jhoan Toro-Mendoza , Alberto Striolo

Biological tissues have been observed to display emergent fluid-like properties, owing to physical interactions between cells. However, it remains unclear in general how these fluid-like properties affect tissue structure and function.…

软凝聚态物质 · 物理学 2026-02-24 Giulia L. Celora , Benjamin J. Walker , Mohit P. Dalwadi , Philip Pearce

One of the hypothesized functions of biomolecular condensates is to act as chemical reactors, where chemical reactions can be modulated, i.e. accelerated or slowed down, while substrate molecules enter and products exit from the condensate.…

生物物理 · 物理学 2024-07-02 Alexandra Shelest , Hugo Le Roy , Daniel M. Busiello , Paolo De Los Rios

We derive a microscopic expression for a quantity $\mu$ that plays the role of chemical potential of Active Brownian Particles (ABPs) in a steady state in the absence of vortices. We show that $\mu$ consists of (i) an intrinsic chemical…

软凝聚态物质 · 物理学 2018-01-17 Siddharth Paliwal , Jeroen Rodenburg , René van Roij , Marjolein Dijkstra

Although coarse-grained models have been widely used to explain exotic phenomena in complex fluids, such as droplet formation in living cells, these conventional approaches often fail to capture the intricate microscopic degrees of freedom…

软凝聚态物质 · 物理学 2025-06-13 Masanari Shimada , Tetsuya J. Kobayashi

The two-dimensional Active Brownian Particles system is meant to be composed of hard disks, that show excluded volume interactions, usually simulated via molecular dynamics using pure repulsive potentials. We show that the softness of the…

Recently, there has been much interest in activity-induced phase separations in concentrated suspensions of "active Brownian particles" (ABPs), self-propelled spherical particles whose direction of motion relaxes through thermal rotational…

软凝聚态物质 · 物理学 2014-02-13 Joakim Stenhammar , Davide Marenduzzo , Rosalind J. Allen , Michael E. Cates

In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the behavior of synthetic or living active matter. Great progress…

软凝聚态物质 · 物理学 2025-08-29 Q. Martinet , Y. Li , A. Aubret , E. Hannezo , J. Palacci

Phase separation, crucial for spatially segregating biomolecules in cells, is well-understood in the simple case of a few components with pairwise interactions. Yet, biological cells challenge the simple picture in at least two ways: First,…

软凝聚态物质 · 物理学 2024-03-12 Chengjie Luo , Yicheng Qiang , David Zwicker