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Automatic segmentation of lesions in FDG-18 Whole Body (WB) PET/CT scans using deep learning models is instrumental for determining treatment response, optimizing dosimetry, and advancing theranostic applications in oncology. However, the…

图像与视频处理 · 电气工程与系统科学 2023-11-06 Gowtham Krishnan Murugesan , Diana McCrumb , Eric Brunner , Jithendra Kumar , Rahul Soni , Vasily Grigorash , Stephen Moore , Jeff Van Oss

To improve the accessibility of smart devices and to simplify their usage, building models which understand user interfaces (UIs) and assist users to complete their tasks is critical. However, unique challenges are proposed by UI-specific…

计算机视觉与模式识别 · 计算机科学 2021-08-11 Chongyang Bai , Xiaoxue Zang , Ying Xu , Srinivas Sunkara , Abhinav Rastogi , Jindong Chen , Blaise Aguera y Arcas

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

图像与视频处理 · 电气工程与系统科学 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Synthetic lethality (SL) prediction is used to identify if the co-mutation of two genes results in cell death. The prevalent strategy is to abstract SL prediction as an edge classification task on gene nodes within SL data and achieve it…

机器学习 · 计算机科学 2023-10-18 Xusheng Zhao , Hao Liu , Qiong Dai , Hao Peng , Xu Bai , Huailiang Peng

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Lung cancer is a leading cause of death worldwide. Early-stage detection of lung cancer is essential for a more favorable prognosis. Radiogenomics is an emerging discipline that combines medical imaging and genomics features for modeling…

图像与视频处理 · 电气工程与系统科学 2022-11-15 Ivo Gollini Navarrete , Mohammad Yaqub

The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

机器学习 · 计算机科学 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

Emerging research has highlighted that artificial intelligence-based multimodal fusion of digital pathology and transcriptomic features can improve cancer diagnosis (grading/subtyping) and prognosis (survival risk) prediction. However, such…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Samiran Dey , Christopher R. S. Banerji , Partha Basuchowdhuri , Sanjoy K. Saha , Deepak Parashar , Tapabrata Chakraborti

Predicting all applicable labels for a given image is known as multi-label classification. Compared to the standard multi-class case (where each image has only one label), it is considerably more challenging to annotate training data for…

计算机视觉与模式识别 · 计算机科学 2021-10-25 Elijah Cole , Oisin Mac Aodha , Titouan Lorieul , Pietro Perona , Dan Morris , Nebojsa Jojic

Modeling label correlations has always played a pivotal role in multi-label image classification (MLC), attracting significant attention from researchers. However, recent studies have overemphasized co-occurrence relationships among labels,…

计算机视觉与模式识别 · 计算机科学 2025-07-10 LeiLei Ma , Shuo Xu , MingKun Xie , Lei Wang , Dengdi Sun , Haifeng Zhao

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

机器学习 · 计算机科学 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Directly predicting human epidermal growth factor receptor 2 (HER2) status from widely available hematoxylin and eosin (HE)-stained whole slide images (WSIs) can reduce technical costs and expedite treatment selection. Accurately predicting…

图像与视频处理 · 电气工程与系统科学 2024-02-28 Bao Li , Zhenyu Liu , Lizhi Shao , Bensheng Qiu , Hong Bu , Jie Tian

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

机器学习 · 计算机科学 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Predicting drug side-effects before they occur is a key task in keeping the number of drug-related hospitalizations low and to improve drug discovery processes. Automatic predictors of side-effects generally are not able to process the…

机器学习 · 统计学 2022-12-01 Pietro Bongini , Elisa Messori , Niccolò Pancino , Monica Bianchini

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

图像与视频处理 · 电气工程与系统科学 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

定量方法 · 定量生物学 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Contrastive, self-supervised learning (SSL) is used to train a model that predicts cancer type from miRNA, mRNA or RPPA expression data. This model, a pretrained FT-Transformer, is shown to outperform XGBoost and CatBoost, standard…

机器学习 · 计算机科学 2023-11-17 Christian John Hurry , Emma Slade

Prediction of genetic biomarkers, e.g., microsatellite instability and BRAF in colorectal cancer is crucial for clinical decision making. In this paper, we propose a whole slide image (WSI) based genetic biomarker prediction method via…

图像与视频处理 · 电气工程与系统科学 2024-07-16 Ling Zhang , Boxiang Yun , Xingran Xie , Qingli Li , Xinxing Li , Yan Wang

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma